|1.||Suzuki, Shigeaki: 7 articles (01/2015 - 08/2011)|
|2.||Kuwana, Masataka: 6 articles (09/2015 - 09/2005)|
|3.||Oddis, Chester V: 6 articles (07/2015 - 01/2004)|
|4.||Nishino, Ichizo: 5 articles (01/2015 - 08/2011)|
|5.||Fertig, Noreen: 4 articles (07/2015 - 01/2004)|
|6.||Hayashi, Yukiko K: 4 articles (01/2015 - 08/2011)|
|7.||Targoff, Ira N: 4 articles (01/2013 - 07/2005)|
|8.||Benveniste, Olivier: 3 articles (03/2015 - 05/2006)|
|9.||Suzuki, Norihiro: 3 articles (01/2015 - 06/2012)|
|10.||Boyer, Olivier: 3 articles (05/2014 - 05/2006)|
|1.||Muscular Diseases (Myopathy)
01/01/2015 - "[A case of chronic myopathy associated with an antibody to signal recognition particle (SRP) following long-term asymptomatic hypercreatinekinasemia]."
09/30/2014 - "[Anti-signal recognition particle autoantibody positive myopathy]."
01/01/2013 - "[Head drop syndrome in a patient with immune-mediated necrotizing myopathy with anti-signal recognition particle antibody: a case report]."
08/01/2011 - "We describe 2 Japanese girls with anti-signal recognition particle myopathy who developed symptoms from the ages of 5 and 9 years, respectively. "
08/01/2011 - "However, only a few teenage patients with anti-signal recognition particle myopathy have been reported, and to date, to our knowledge, no patient younger than 10 years has been documented. "
|2.||Myositis (Idiopathic Inflammatory Myopathies)
07/01/2015 - "The aim of this study was to develop and validate a quantitative anti-signal recognition particle (SRP) autoantibody serum ELISA in patients with myositis and longitudinal association with myositis disease activity. "
02/01/2015 - "Myositis-specific auto-immune antibody panel was positive for anti-Signal recognition particle and anti-PL-12. "
01/01/2012 - "Anti-signal recognition particle (SRP) antibody, detected in 5-8% of patients with clinical diagnosis of myositis, had been associated with severe and refractory myositis. "
12/01/2006 - "To elucidate the clinical importance of the anti-signal recognition particle (SRP) autoantibody in patients with myositis. "
01/01/2004 - "Anti-signal recognition particle autoantibody in patients with and patients without idiopathic inflammatory myopathy."
09/01/2012 - "Anti-SRP (signal recognition particle) positive necrotizing myopathy is commonly not associated with neoplasms. "
04/01/2011 - "Among them two histones, H2B and H4, were identified in MCL tumor biopsies and the signal recognition particle 9 kDa protein, SRP9, in SLL tumor biopsies."
01/01/2008 - "Signal recognition particle 14 kDa (SRP14), tumor protein, translationally-controlled 1 (TPT1) and eukaryotic elongation factor 1A1 (EEF1A1) were ranked the most stable genes. "
03/01/2005 - "These are involved in nontraditional roles of the nucleolus, including regulation of tumor suppressor and oncogene activities, signal recognition particle assembly, modification of small RNAs, control of aging, and modulating telomerase function."
06/01/2012 - "Predictive factors for a poor prognosis in PM/DM patients are older age, involvement of lung and cardiac systems, dysphagia, cancer, and serum myositis-specific antibodies (including coexistent presence of anti-Ro52 and anti-Jo1 antibodies, anti-signal recognition particle antibody, anti-155/140, and anti-CADM-140 antibodies)."
09/01/2005 - "Autoantibodies against signal recognition particle (SRP) are detected in patients with polymyositis/dermatomyositis (PM/DM). "
01/01/2009 - "To elucidate the clinical and histopathological features associated with autoantibodies to the signal recognition particle (SRP), we have studied 23 Japanese patients with this specificity among 3,500 patients with polymyositis/dermatomyositis and other connective tissue diseases. "
11/01/1991 - "In idiopathic inflammatory myopathy (IIM; or, polymyositis/dermatomyositis), the myositis-specific autoantibodies anti-Jo-1 and anti-signal recognition particle (anti-SRP), appear to define clinically and immunogenetically distinct groups of patients. "
12/25/1998 - "We report that the 72-kDa signal recognition particle (SRP) protein, a rare target of autoantibodies found in the serum of patients with dermatomyositis and systemic lupus erythematosus, is rapidly cleaved in Jurkat T cells treated with apoptotic (i.e. "
11/01/2011 - "Pathologic classification categories include immune myopathies with perimysial pathology (IMPP), a group that can be associated with antisynthetase antibodies; myovasculopathies, including childhood dermatomyositis; immune polymyopathies, active myopathies with little inflammation such as the myopathy with signal recognition particle antibodies; immune myopathies with endomysial pathology (IM-EP), illustrated by brachio-cervical inflammatory myopathy (BCIM); histiocytic inflammatory myopathies, like sarcoid myopathy; and inflammatory myopathies with vacuoles, aggregates and mitochondrial pathology (IM-VAMP), which have inclusion body myositis as a pathologic subtype and are poorly treatable. "
|5.||Interstitial Lung Diseases (Interstitial Lung Disease)
01/01/2010 - "[A case of interstitial pneumonia with anti-signal recognition particle (SRP) antibody without myopathy]."
05/01/2008 - "Anti-signal recognition particle (anti-SRP) is a myositis-specific autoantibody that is linked to a severe polymyositis (PM) associated with interstitial lung disease (ILD) and esophageal dysmotility in adults. "
10/01/2007 - "Diffuse cutaneous type, erosive esophagitis, and myositis were more common in group 1 than in group 2 (p = 0.007, 0.003, and 0.003, respectively) or group 3 (p = 0.04, 0.002, and 0.01, respectively), whereas interstitial lung disease (ILD) was more frequent in group 2 (p = 0.005) and group 3 (p = 0.02) versus group 1. Antinuclear antibodies showed a nucleolar pattern significantly more frequently in group 1. Myositis-related autoantibodies, including anti-U1RNP, anti-U3RNP, anti-Ku, and anti-signal recognition particle antibodies, were observed in 57% of group 1. Our findings strongly suggest the existence of a subgroup of SSc patients with severe GIT involvement in the early stage. "
04/01/1992 - "Antibodies to aminoacyl transfer RNA (tRNA) synthetases and the signal recognition particle (SRP) were found to be specific for PM/DM: PM/DM patients with antibodies to 3 aminoacyl-tRNA synthetases (histidyl, threonyl, and glycyl) appeared to form a distinct clinical subset, associated with chronic interstitial lung disease, polyarthritis, and myositis, while 3 patients with antibodies that bound the SRP had severe myositis that was resistant to corticosteroid therapy. "
09/01/2014 - "Two investigators independently extracted data on study design, patient characteristics, and clinical features (interstitial lung disease [ILD], fever, mechanic's hands [MH], Raynaud's phenomenon [RPh], arthralgia, sclerodactyly, cancer and dermatomyositis-specific rash) according to the presence of myositis-specific (anti-aminoacyl-transfer RNA synthetase [ARS], anti-signal recognition particle [anti-SRP] and anti-Mi2) and myositis-associated (anti-PM/Scl, anti-U1-RNP and anti-Ku) autoantibodies. "
|5.||Amino Acyl-tRNA Synthetases (Aminoacyl-tRNA Synthetase)
|7.||Transfer RNA (tRNA)
|10.||3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA)