Adrenocortical Carcinoma

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614 relevant articles (19 outcomes, 56 trials/studies) found for this Disease

Description: A malignant neoplasm of the ADRENAL CORTEX. Adrenocortical carcinomas are unencapsulated anaplastic (ANAPLASIA) masses sometimes exceeding 20 cm or 200 g. They are more likely to be functional than nonfunctional, and produce ADRENAL CORTEX HORMONES that may result in hypercortisolism (CUSHING SYNDROME); HYPERALDOSTERONISM; and/or VIRILISM.

Also Known As:

Carcinoma, Adrenocortical; Adrenal Cortical Carcinoma; Adrenal Cortical Carcinomas; Adrenocortical Carcinomas; Carcinomas, Adrenal Cortical; Carcinomas, Adrenocortical; Carcinoma, Adrenal Cortical

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Neoplasms (Cancer)
2.	Carcinoma (Carcinomatosis)
3.	Cushing Syndrome
4.	Ectopic ACTH Syndrome
5.	Adrenocortical Adenoma (Disease, Conn's)
83 Diseases and 265 more articles analyzed in the Full Patient-Physician Summary Report, order at left...

Experts

1.	Fassnacht, Martin: 5 articles (06/2008 - 04/2005)
2.	Hahner, Stefanie: 4 articles (06/2008 - 04/2005)
3.	van den Berg, Martin: 4 articles (12/2005 - 07/2002)
4.	Sanderson, J Thomas: 4 articles (12/2005 - 07/2002)
5.	Allolio, Bruno: 3 articles (06/2008 - 11/2006)
6.	Giesy, John P: 3 articles (04/2007 - 12/2005)
7.	Nussdorfer, Gastone G: 3 articles (12/2005 - 03/2005)
8.	Totsune, K: 3 articles (07/2001 - 02/2000)
9.	Takahashi, K: 3 articles (07/2001 - 02/2000)
10.	Shibahara, S: 3 articles (07/2001 - 02/2000)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Adrenocortical Carcinoma:

1.	Mitotane (Lysodren)FDA Link 07/01/2001 - "The excellent follow-up of these patients suggests that even in hopeless cases with metastatic adrenocortical carcinoma, mitotane should be administered for very long periods of time as it can be well-tolerated and may be beneficial in the long run." 01/01/1994 - "Complete remission of metastasized adrenocortical carcinoma under o,p'-DDD." 07/01/1990 - "Unlike previous reports of metastatic adrenal cortical carcinoma in which complete remission was obtained with high dose Mitotane treatment, the dose of Mitotane used in this patient was low" 01/01/2001 - "For adrenocortical carcinoma, adjunctive treatment with oral mitotane leads to well-documented improvement of survival" 12/01/1999 - "Changes in neoplastic cell features and sensitivity to mitotane during mitotane-induced remission in a patient with recurrent, metastatic adrenocortical carcinoma." Get all the results and reference details, order at left...
2.	HormonesIBA 02/15/2008 - "In this study, the steroidogenic effects of hydroxylated, methoxylated and/or chlorinated derivatives of PBDEs were assessed at both the gene and enzyme/hormone levels in the H295R human adrenocortical carcinoma cell line" 01/01/1984 - "This study concerns the history of a male patient with hormone-producing adrenal cortical carcinoma" 11/15/2006 - "To identify and prioritize chemicals that may alter steroidogenesis, an in vitro screening assay based on measuring alterations in hormone production was developed using the H295R human adrenocortical carcinoma cell line" 12/01/2001 - "DESIGN AND METHODS: Twenty-one patients with adrenocortical carcinoma (11 nonfunctioning and 10 hormone-secreting) were investigated with 75Se-methyl-nor-cholesterol scintigraphy" 03/01/1993 - "NCI-H295 is a recently described human adrenocortical carcinoma cell line that makes a variety of steroid hormones" Get all the results and reference details, order at left...
3.	Suramin (Suramin Sodium)