Small Cell Sarcoma

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10 relevant articles (0 outcomes, 1 trials/studies) found for this Disease

Description: A sarcoma characterized by the presence of small cells, cells measuring 9-14 micrometers with a faint or indistinct rim of cytoplasm and an oval-to-elongated nucleus with relatively dense chromatin. (From Segen, Dictionary of Modern Medicine, 1992)

Also Known As:

Sarcoma, Small Cell; Cell Sarcoma, Small; Cell Sarcomas, Small; Sarcomas, Small Cell; Small Cell Sarcomas

Disease Context: Research Results

Neoplasms: 387500

Neoplasms by Histologic Type: 1

Connective and Soft Tissue Neoplasms

Sarcoma: 10281

Small Cell Sarcoma: 10

Connective Tissue Neoplasms: 6

Small Cell Sarcoma: 10

Related Diseases

1.	Osteosarcoma (Osteogenic Sarcoma)
2.	Sarcoma (Soft Tissue Sarcoma)
3.	Neoplasms (Cancer)
4.	Mesenchymal Chondrosarcoma
5.	Synovial Sarcoma (Synovioma)

Experts

1.	Söder, Stephan: 1 article (08/2005)
2.	Oliveira, André M: 1 article (08/2005)
3.	Aigner, Thomas: 1 article (08/2005)
4.	Inwards, Carrie Y: 1 article (08/2005)
5.	Müller, Susanna: 1 article (08/2005)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Small Cell Sarcoma:

1.	Collagen Type II (Type II Collagen)IBA 08/01/2005 - "Type II collagen as specific marker for mesenchymal chondrosarcomas compared to other small cell sarcomas of the skeleton." 08/01/2005 - "In our study on a large series of mesenchymal chondrosarcomas (n=30) and other small cell sarcomas (Ewing's sarcomas (n=12), synovial sarcomas (n=6), hemangiopericytomas (n=5), small cell osteosarcomas (n=3), and desmoplastic small round cell tumors (n=1)), we could establish the presence of type II collagen in the extracellular tumor matrix of the small cell areas of mesenchymal chondrosarcomas as a specific and sensitive marker to identify mesenchymal chondrosarcomas and to exclude other small cell neoplasms (except chondroblastic areas in small cell osteosarcomas)" Order ALL the reference details at left...
2.	N 30IBA 08/01/2005 - "In our study on a large series of mesenchymal chondrosarcomas (n=30) and other small cell sarcomas (Ewing's sarcomas (n=12), synovial sarcomas (n=6), hemangiopericytomas (n=5), small cell osteosarcomas (n=3), and desmoplastic small round cell tumors (n=1)), we could establish the presence of type II collagen in the extracellular tumor matrix of the small cell areas of mesenchymal chondrosarcomas as a specific and sensitive marker to identify mesenchymal chondrosarcomas and to exclude other small cell neoplasms (except chondroblastic areas in small cell osteosarcomas)" Order ALL the reference details at left...
3.	tranilast (N 5')IBA 08/01/2005 - "In our study on a large series of mesenchymal chondrosarcomas (n=30) and other small cell sarcomas (Ewing's sarcomas (n=12), synovial sarcomas (n=6), hemangiopericytomas (n=5), small cell osteosarcomas (n=3), and desmoplastic small round cell tumors (n=1)), we could establish the presence of type II collagen in the extracellular tumor matrix of the small cell areas of mesenchymal chondrosarcomas as a specific and sensitive marker to identify mesenchymal chondrosarcomas and to exclude other small cell neoplasms (except chondroblastic areas in small cell osteosarcomas)" Order ALL the reference details at left...
4.	Progesterone Receptors (Progesterone Receptor)IBA 10/01/1989 - "Of the 26 samples assayed for progesterone receptors, measurable bindings were found in 14 of 17 meningiomas, 1 of 2 astrocytomas, 1 malignant lymphoma, 1 hemangioblastoma, 1 ganglioglioma, 1 glioblastoma multiforme, 1 anaplastic ependymoma, 1 small cell sarcoma, and 1 neurilemoma" Order ALL the reference details at left...
5.	Cyclophosphamide (Cytoxan)FDA Link 07/01/1976 - "B., who was receiving cyclophosphamide (CY) for chemotherapy of a localized undifferentiated small cell sarcoma of the chest wall, developed generalized urticaria on three separate occasions immediately after CY administration" Order ALL the reference details at left...
6.	AntibodiesIBA 01/01/2003 - "The use of a wide panel of antibodies confirmed (in 74% of the cases) and corrected (in 26%) the diagnosis of a diversity of small cell sarcomas established by routine methods" Order ALL the reference details at left...

Therapies and Procedures

1.	Drug Therapy (Chemotherapy) 10/30/2005 - "Chemotherapy may also be used following local treatment, although the role of adjuvant chemotherapy is better defined in small-cell sarcomas" 10/30/2005 - "The principles of chemotherapy used for primary bone neoplasms are essentially similar in spindle-cell and small-cell sarcomas" 01/01/1999 - "The use of chemotherapy is justified only in small-cell sarcomas in which metastasis occurs frequently and chemotherapy is known to be effective" 04/01/1989 - "The chemotherapy protocol described by Rosen was selected according to histological classification of sarcomas (small cell sarcoma, spindle cell sarcoma, pleomorphic sarcoma)" 10/01/1989 - "Osteosarcoma, rhabdomyosarcoma, Ewing's sarcoma, and other small-cell sarcomas are sensitive to chemotherapy, which should be given preoperatively, continued postoperatively, and modified according to the tumor response" Order ALL the reference details at left...
2.	Adjuvant Chemotherapy 10/30/2005 - "Chemotherapy may also be used following local treatment, although the role of adjuvant chemotherapy is better defined in small-cell sarcomas" Order ALL the reference details at left...
3.	Heterologous Transplantation (Xenotransplantation) 06/01/1994 - "In two cases the primary xenografts (teratocarcinoma and small-cell sarcoma) were retransplanted into 11 CsA-immunosuppressed rats" Order ALL the reference details at left...
4.	Combination Drug Therapy (Combination Chemotherapy) 04/01/1983 - "According to this subclassification, patients with the small cell type of lesions responded to combination chemotherapy and irradiation, as usually do other small cell sarcomas" Order ALL the reference details at left...

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