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Myofibromatosis

A condition characterized by multiple formations of myofibromas (LEIOMYOMA).
Also Known As:
Myofibromatoses
Networked: 74 relevant articles (2 outcomes, 3 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Neoplasms (Cancer)
2. Myofibroma
3. Turner Syndrome (Turner's Syndrome)
4. Fibroma (Fibromatosis)
5. Dermatofibrosarcoma

Experts

1. Arts, Florence A: 4 articles (01/2022 - 01/2017)
2. Demoulin, Jean-Baptiste: 4 articles (01/2022 - 01/2017)
3. Dachy, Guillaume: 3 articles (01/2022 - 01/2017)
4. Fraitag, Sylvie: 3 articles (01/2021 - 07/2017)
5. Bly, Randall A: 2 articles (02/2022 - 01/2020)
6. Dahl, John P: 2 articles (02/2022 - 01/2020)
7. Perkins, Jonathan A: 2 articles (02/2022 - 01/2020)
8. Wenger, Tara L: 2 articles (02/2022 - 01/2020)
9. Wu, Natalie: 2 articles (02/2022 - 01/2020)
10. Bodemer, Christine: 2 articles (01/2021 - 07/2017)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Myofibromatosis:
1. Interferon-alpha (Interferon Alfa)IBA
2. Platelet-Derived Growth Factor beta Receptor (Receptor, Platelet Derived Growth Factor beta)IBA
3. Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA
4. Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA
5. Phosphotransferases (Kinase)IBA
6. Imatinib Mesylate (Gleevec)FDA Link
7. Vinblastine (Vinblastine Sulfate)FDA Link
8. Platelet-Derived Growth FactorIBA
9. Methotrexate (Mexate)FDA LinkGeneric
10. DesminIBA
09/01/1992 - "In two patients with infantile myofibromatosis a coexpression of actin and desmin was found. "
05/01/1998 - "These lesions include: fibromatoses in adults and infants (infantile digital fibromatosis and infantile myofibromatosis); myofibroma of adults, an almost exclusively solitary lesion in the skin which is characterized morphologically as a biphasic lesion composed of spindle-shaped eosinophilic tumour cells and more primitive mesenchymal tumour cells associated with a haemangiopericytoma-like vasculature; dermatomyofibroma (plaque-like dermal fibromatosis), a band-like myofibroblastic proliferation in young female patients, which is mainly located in the periaxillar region and in which distinction from more aggressive, plaque-like variant of dermatofibrosarcoma protuberans is mandatory; myofibroblastoma of the breast, a well-circumscribed lesion composed of spindle shaped, desmin-positive tumour cells, which is seen mainly in elderly male patients and has to be distinguished from other spindle cell lesions of the breast; angiomyofibroblastoma, a well-circumscribed myofibroblastic neoplasm of the vulva and vagina composed of avoid to round myoid tumour cells with scattered multinucleated cells, which forms a continuous morphological spectrum with the clinically more aggressive angiomyxoma in this location; intranodal myofibroblastoma, a distinctive proliferation of myofibroblastic cells associated with so-called amianthoid fibres, which is seen most commonly in inguinal lymph nodes; myofibroblastoma/myofibroblastic tumour of soft tissues, a variably well-circumscribed myofibroblastic lesion which lacks atypia and is composed of actin and/or desmin positive tumour cells, and poorly delineated sarcomas with myofibroblastic differentiation (myofibrosarcoma)."

Therapies and Procedures

1. Therapeutics
2. Drug Therapy (Chemotherapy)
3. Critical Care (Surgical Intensive Care)
4. Operative Surgical Procedures
5. Conservative Treatment