A condition characterized by multiple formations of myofibromas (LEIOMYOMA).
Also Known As:
Networked: 42 relevant articles (2 outcomes, 1 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Turner Syndrome (Turner's Syndrome)
2. Neoplasms (Cancer)
3. Fibroma (Fibromatosis)
4. Malignant Fibrous Histiocytoma
5. Benign Fibrous Histiocytoma (Dermatofibroma)


1. Sapp, Julie: 1 article (09/2015)
2. Rademakers, Rosa: 1 article (09/2015)
3. Cormier-Daire, Valerie: 1 article (09/2015)
4. Biesecker, Leslie G: 1 article (09/2015)
5. Johnston, Jennifer J: 1 article (09/2015)
6. Crenshaw, Molly: 1 article (09/2015)
7. Keppler-Noreuil, Kim M: 1 article (09/2015)
8. Sanchez-Contreras, Monica Y: 1 article (09/2015)
9. Finch, NiCole A: 1 article (09/2015)
10. Sybert, Virginia P: 1 article (09/2015)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Myofibromatosis:
1. Interferon-alpha (Interferon Alfa)FDA Link
2. Dermatofibrosarcoma protuberansIBA
06/01/2003 - "The main differential diagnosis includes hypertrophic scar, dermatofibroma (fibrous histiocytoma), pilar leiomyoma, neurofibroma, adult myofibromatosis, extra-abdominal fibromatosis and plaque-stage dermatofibrosarcoma protuberans. "
11/01/2005 - "Ultrastructural features are described of nodular fasciitis, the myofibromatoses (including Dupuytren's disease), inflammatory myofibroblastic tumour, post-operative spindle cell nodule, fibroma of tendon sheath, fibrous pseudotumour, benign fibrous histiocytoma, atypical fibroxanthoma, dermatofibrosarcoma protuberans, myofibrosarcoma (myofibroblastic sarcoma), malignant fibrous histiocytoma (pleomorphic myofibrosarcoma), epithelioid sarcoma and spindle-cell carcinoma. "
05/01/1987 - "Diagnoses included infantile digital fibromatosis, "aggressive fibromatosis," aggressive fibromatosis progressing to poorly differentiated sarcoma, infantile myofibromatosis, recurrent desmoid tumor, fibrosarcoma arising in a keloid, dermatofibrosarcoma protuberans, and malignant fibrous histiocytoma of left atrium. "
02/01/2015 - "There are different types of fibroblastic and myofibroblastic tumors that can involve the head and neck including desmoid-type fibromatosis, solitary fibrous tumor, myofibroma/myofibromatosis, nodular fasciitis, nasopharyngeal angiofibroma, fibrosarcoma, dermatofibrosarcoma protuberans, fibromatosis coli, inflammatory myofibroblastic tumor, ossifying fibroma, fibrous histiocytoma, nodular fasciitis, fibromyxoma, hyaline fibromatosis and fibrous hamartoma. "
12/01/2007 - "Quantitative real-time polymerase chain reaction was used to examine the expression level of alpha and beta isoforms of PDGF/R in 17 fibromatoses, four myofibromatoses and three dermatofibrosarcoma protuberans (DFSP) in children. "
3. Platelet-Derived Growth Factor beta Receptor (Receptor, Platelet Derived Growth Factor beta)IBA
4. tebufenozide (Mimic)IBA
5. DesminIBA
09/01/1992 - "In two patients with infantile myofibromatosis a coexpression of actin and desmin was found. "
05/01/1998 - "These lesions include: fibromatoses in adults and infants (infantile digital fibromatosis and infantile myofibromatosis); myofibroma of adults, an almost exclusively solitary lesion in the skin which is characterized morphologically as a biphasic lesion composed of spindle-shaped eosinophilic tumour cells and more primitive mesenchymal tumour cells associated with a haemangiopericytoma-like vasculature; dermatomyofibroma (plaque-like dermal fibromatosis), a band-like myofibroblastic proliferation in young female patients, which is mainly located in the periaxillar region and in which distinction from more aggressive, plaque-like variant of dermatofibrosarcoma protuberans is mandatory; myofibroblastoma of the breast, a well-circumscribed lesion composed of spindle shaped, desmin-positive tumour cells, which is seen mainly in elderly male patients and has to be distinguished from other spindle cell lesions of the breast; angiomyofibroblastoma, a well-circumscribed myofibroblastic neoplasm of the vulva and vagina composed of avoid to round myoid tumour cells with scattered multinucleated cells, which forms a continuous morphological spectrum with the clinically more aggressive angiomyxoma in this location; intranodal myofibroblastoma, a distinctive proliferation of myofibroblastic cells associated with so-called amianthoid fibres, which is seen most commonly in inguinal lymph nodes; myofibroblastoma/myofibroblastic tumour of soft tissues, a variably well-circumscribed myofibroblastic lesion which lacks atypia and is composed of actin and/or desmin positive tumour cells, and poorly delineated sarcomas with myofibroblastic differentiation (myofibrosarcoma)."
6. CollagenIBA
7. beta CateninIBA
8. Collagen Type IV (Type IV Collagen)IBA
9. Platelet-Derived Growth Factor alpha ReceptorIBA
10. Protein Isoforms (Isoforms)IBA

Therapies and Procedures

1. Drug Therapy (Chemotherapy)
2. Intensive Care (Surgical Intensive Care)
3. Pancreaticoduodenectomy
4. Kidney Transplantation
5. Tissue Expansion