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Desmoplastic Fibroma

A extremely rare bone tumor characterized by abundant collagen formation and a fibrous stroma, without evidence of mitosis or pleomorphism. It appears on x-rays as an osteolytic lesion with well-defined margins and must be differentiated from primary fibrosarcoma of bone. (DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1441)
Also Known As:
Fibroma, Desmoplastic; Desmoplastic Fibromas; Fibromas, Desmoplastic
Networked: 16 relevant articles (0 outcomes, 2 trials/studies) for this Disease, Comments

Disease Context: Research Results

Related Diseases

1. Aggressive Fibromatosis (Desmoid)
2. Neoplasms (Cancer)
3. Fibroma (Fibromatosis)
4. Hemangiosarcoma (Angiosarcoma)
5. Giant Cell Tumors (Giant Cell Tumor)

Experts

1. Makni, S: 1 article (09/2009)
2. Karray, F: 1 article (09/2009)
3. Dhouib, M: 1 article (09/2009)
4. Chemli, H: 1 article (09/2009)
5. Abdelmoula, M: 1 article (09/2009)
6. Yavas, Ayse: 1 article (09/2005)
7. Van Marck, Eric: 1 article (09/2005)
8. Kroon, Herman M: 1 article (09/2005)
9. Jundt, Gernot: 1 article (09/2005)
10. Hogendoorn, Pancras C W: 1 article (09/2005)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Desmoplastic Fibroma:
1. beta CateninIBA
2. ParaffinIBA
3. Cyclin D1IBA
4. Progesterone Receptors (Progesterone Receptor)IBA
5. Indomethacin (Indometacin)FDA LinkGeneric
6. GadoliniumIBA
01/01/2001 - "Desmoplastic fibroma showed a distinct, inhomogeneous gadolinium enhancement. "
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7. Estrogens (Estrogen)FDA Link
8. CollagenIBA
9. Ascorbic Acid (Vitamin C)FDA Link

Therapies and Procedures

1. Curettage
2. Homologous Transplantation (Allograft)
3. Spinal Fusion (Spondylosyndesis)
4. Radiotherapy
06/01/2003 - "Radiotherapy for desmoplastic fibroma of bone: a case report."
12/01/1995 - "Desmoplastic fibroma: a role for radiotherapy?"
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5. Transplants (Transplant)
03/01/1999 - "Desmoplastic fibroma of the calcaneus treated with a microvascular bone graft. "
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