Benign Fibrous Histiocytoma (Dermatofibroma)

203  relevant articles (4 outcomes, 14 trials/studies) found for this Disease

Dermatofibroma; Dermatofibromas; Histiocytoma, Benign Fibrous; Angioma, Sclerosing; Angiomas, Sclerosing; Benign Fibrous Histiocytomas; Cutaneous Histiocytoma; Cutaneous Histiocytomas; Fibrous Histiocytoma; Fibrous Histiocytoma, Benign; Fibrous Histiocytomas; Fibrous Histiocytomas, Benign; Hemangiomas, Sclerosing; Histiocytomas, Benign Fibrous; Histiocytomas, Cutaneous; Histiocytomas, Fibrous; Sclerosing Angioma; Sclerosing Angiomas; Sclerosing Hemangioma; Sclerosing Hemangiomas; Hemangioma, Sclerosing; Histiocytoma, Cutaneous; Histiocytoma, Fibrous

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Dermatofibrosarcoma
2.	Malignant Fibrous Histiocytoma
3.	Sarcoma (Soft Tissue Sarcoma)
4.	Keloid
5.	Nevus (Nevi)

Experts

1.	McConnell, I: 2 articles (07/2008 - 04/2008)
2.	Baines, S J: 2 articles (07/2008 - 04/2008)
3.	McInnes, E F: 2 articles (07/2008 - 04/2008)
4.	McCalmont, Timothy H: 1 article (08/2008)
5.	de Feraudy, Sebastien: 1 article (08/2008)
6.	Mar, Natalie: 1 article (08/2008)
7.	Rodrigues, P: 1 article (07/2008)
8.	Queiroga, F L: 1 article (07/2008)
9.	Lopes, C S: 1 article (07/2008)
10.	Pires, I: 1 article (07/2008)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Benign Fibrous Histiocytoma:

1.	Factor XIIIaIBA 08/01/2005 - "OBJECTIVES: In this study, we examined the fine structures and potential heterogeneity among the subgroup of factor XIIIa (FXIIIa) positive dendritic cells consisted of eleven cases of dermatofibroma (DF)" 07/01/2005 - "The digital AFs, fibrokeratomas, and dermatofibromas stained predominately for Factor XIIIa, with no or minimal staining for CD34" 11/01/2002 - "Aneurysmal fibrous histiocytoma showing transition from factor XIIIa-positive to -negative." 04/01/2002 - "Benign fibrous histiocytoma: an additional case richly endowed with factor XIIIa(+) cells." 09/01/1997 - "In contrast to classic Schwannian/neurogenic granular cell tumours, granular cell dermatofibromas were S100 protein negative, but showed variable reactivity for factor XIIIa (10-50%) in 4/5, for smooth muscle specific actin (10-50%) in 2/5 and with E9 (10-30%) in 3/5 lesions" Order ALL the reference details at left...
2.	dasatinib (BMS 354825)FDA Link 03/01/2007 - "Dasatinib is likely to be effective against dermatofibroma sarcoma protuberans and cutaneous acute lymphoblastic leukemia, and has caused panniculitis" Order ALL the reference details at left...
3.	Muramidase (Lysozyme)IBA 11/01/1985 - "In this study the immunohistochemical analysis of distinct morphologic variants of benign fibrous histiocytoma (BFH) of the skin was performed with immunoperoxidase technique for both lysozyme and alpha-1-antitrypsin (A1AT)" 11/01/1986 - "The marked heterogeneity in lysozyme expression in cutaneous histiocytoma may indicate that a proportion of these tumors show relatively primitive histiocytic differentiation and do not express lysozyme" 11/01/1986 - "Lysozyme was less reliable as a histiocytic marker in cutaneous histiocytoma; forty percent of these tumors were negative for lysozyme expression" 11/01/1982 - "Cells positive for lysozyme were found only in 13 out of 100 cases of dermatofibroma, one out of 4 cases of xanthogranuloma and 8 out of 33 cases of malignant fibrous histiocytoma" 11/01/1986 - "Lysozyme was not detectable in the tumor cells in lymphomatoid granulomatosis, atypical cutaneous histiocytoma, and histiocytic lymphosarcoma" Order ALL the reference details at left...
4.	ParaffinIBA 08/01/1997 - "In this study, we investigated this role by immunohistochemically staining PDGF and PDGF beta-receptors in paraffin-embedded dermatofibroma (DF), dermatofibrosarcoma protuberans (DFSP) and malignant fibrous histiocytoma (MFH) tissue" 03/01/2004 - "HSP47 staining on paraffin sections from diseased skin specimens revealed that skin ulcer, keloid, nodular fascitis, spindle cell lipoma, and dermatofibroma had strong signals for HSP47 compared with the signals obtained from normal skin" 05/01/2006 - "The expressions of p-STAT3 and p-ERK were analyzed by immunohistochemical staining in formalin-fixed, paraffin-embedded tissue sections of human DFSP and dermatofibroma" 12/01/1995 - "In addition DNA from six other patients with sclerosing hemangioma was analyzed with paraffin-embedded sections" 01/01/1987 - "Using the PAP technique and the indirect immunofluorescence method, paraffin sections of formaldehyde fixed tissue specimens of 25 tumours (12 benign fibrous histiocytomas, 12 malignant fibrous histiocytomas, and 1 atypical fibroxanthoma) were studied" Order ALL the reference details at left...
5.	AntigensIBA 10/01/1993 - "The consistent presence of CD-34 within all 13 cases of dermatofibrosarcoma protuberans can be used as evidence in support of the view that these lesions are variants of nerve sheath tumors, and distinct from benign fibrous histiocytomas which consistently lack the antigen" 12/01/1994 - "RM 3/1 antigen shows a similar, but broader expression pattern including non-Langerhans cell histiocytoses, xanthelasmata palpebrarum, foreign body granulomas, granuloma annulare, and cellular type dermatofibroma" 11/01/1987 - "Characteristic round stromal cells, which were considered to be the main component of the sclerosing hemangioma, consisted of immunohistochemically heterogenous cells, that is, positive findings were attained with all three antigens, surfactant apoprotein- and EMA-positive ones, SC- and EMA-positive ones, only EMA-positive ones, and all three negative" 01/01/1988 - "An immunohistochemical study of six giant cell tumors of bone and eight related lesions (aneurysmal bone cyst, fibrous histiocytoma, and giant cell tumor of tendon sheath) was performed using a panel of monoclonal antibodies directed to the Ia and monocyte-macrophage lineage antigens" 02/01/2005 - "We evaluated staining for antibodies directed against these two antigens in 202 spindle cell tumors, including cases of follicular dendritic cell tumor (n=14), interdigitating dendritic cell tumor (n=7), leiomyosarcoma (n=17), inflammatory myofibroblastic tumor (n=13), inflammatory pseudotumor (n=2), spindle cell thymoma (n=17), synovial sarcoma (n=11), fibrosarcoma (n=14), liposarcoma (n=27), gastrointestinal stromal tumor (n=13), malignant fibrous histiocytoma (n=18), angiomatoid fibrous histiocytoma (n=4), angiosarcoma (n=10), malignant peripheral nerve sheath tumor (n=8), malignant melanoma (n=16), and spindle cell carcinoma (n=11)" Order ALL the reference details at left...
6.	ApoproteinsIBA 09/01/1993 - "In this study, thirteen cases of sclerosing hemangiomas were analyzed by immunohistochemistry for various histochemical markers including surfactant apoprotein" 01/01/1984 - "In the two cases of sclerosing hemangiomas, the type II pneumocytes were exuberant and numerous, and in one case contained intranuclear inclusions of surfactant apoprotein" 09/15/1989 - "The cytoplasm of some of the sclerosing hemangioma tumor cells was positive for the anti-lung surfactant apoprotein monoclonal antibody (PE-10)" 01/01/1984 - "Bronchioloalveolar carcinomas (n = 45), intravascular bronchiolo-alveolar tumors (n = 8), and sclerosing hemangiomas of the lung (n = 2) were stained for surfactant apoprotein by the immunoperoxidase method" 11/01/1987 - "Characteristic round stromal cells, which were considered to be the main component of the sclerosing hemangioma, consisted of immunohistochemically heterogenous cells, that is, positive findings were attained with all three antigens, surfactant apoprotein- and EMA-positive ones, SC- and EMA-positive ones, only EMA-positive ones, and all three negative" Order ALL the reference details at left...
7.	alpha 1-Antitrypsin (alpha 1 Antitrypsin)IBA 08/01/1986 - "We performed an immunohistochemical study of 24 giant-cell tumors of bone and 30 other lesions (fibrous histiocytoma, nonossifying fibroma, and giant-cell tumor of the tendon sheath) using lysozyme and alpha 1-antitrypsin as markers for histiocytic cells" 10/01/1985 - "We have studied the possible origin of histiocytic cells, present in fibrous histiocytomas (MFH) by using immunohistochemistry to demonstrate lysozyme, alpha 1-antitrypsin, alpha 1-antichymotrypsin and receptors for peanut and soy bean agglutinin in tumour cells of MFH compared with their presence in tumour cells of malignant histiocytosis (MH) ('true' histiocytic lymphoma, 'true' histiocytic sarcoma)" 09/01/1982 - "These results and the observations made on the cutaneous fibrous histiocytomas, atypical fibroxanthomas, dermatofibrosarcoma protuberans, and the various soft tissue sarcomas indicated that 1) alpha 1-antitrypsin is a valuable marker of histiocytic differentiation in both benign and malignant fibrous histiocytomas, 2) ferritin can be visualized in more than half of these fibroblastic-histiocytic tumors, and the presence of ferritin distinguishes the spindle cells of these tumors from fibroblasts of connective tissue and most fibrosarcomas, and 3) lysozyme, although a good marker of histiocytic differentiation in ordinary histiocytes and benign fibrous histiocytomas, is a poor marker of neoplastic histiocytes of malignant tumors" Order ALL the reference details at left...
8.	Matrix MetalloproteinasesIBA 10/01/2004 - "Immunohistochemical expression of matrix metalloproteinases 1, 2, 9, and 14 in dermatofibrosarcoma protuberans and common fibrous histiocytoma (dermatofibroma)." 02/01/2002 - "Immunohistochemical study of membrane type-matrix metalloproteinases (MT-MMPs) and matrix metalloproteinase-2 (MMP-2) in dermatofibroma and malignant fibrous histiocytoma." Order ALL the reference details at left...
9.	CholesterolIBA 03/01/2006 - "OBJECTIVE: The goal of this study was to investigate the relationship between lipidized dermatofibromas and patient age, anatomic location, and serum total cholesterol" 04/01/1990 - "A 63-year-old woman with fibrous histiocytomas showed cholesterol deposition in the setting of type IIB hyperlipidemia" Order ALL the reference details at left...
10.	Monoclonal AntibodiesIBA 01/01/1988 - "An immunohistochemical study of six giant cell tumors of bone and eight related lesions (aneurysmal bone cyst, fibrous histiocytoma, and giant cell tumor of tendon sheath) was performed using a panel of monoclonal antibodies directed to the Ia and monocyte-macrophage lineage antigens" 06/01/1997 - "METHODS: Immunocytochemistry with anti-LN-2 and anti-CD34 monoclonal antibodies on formalin fixed, paraffin embedded material was performed on 102 spindle cell lesions, including dermatofibroma, dermatofibrosarcoma protuberans, atypical fibroxanthoma, malignant fibrous histiocytoma, leiomyoma, and neurofibroma" Order ALL the reference details at left...

Therapies and Procedures

1.	Cryosurgery 02/01/1975 - "Cryosurgery in dermatologic office practice: special reference to dermatofibroma and mucous cyst of the lip." 04/01/1999 - "MAIN MESSAGE: Evidence from case report and series suggests that cryosurgery is effective for actinic keratoses, seborrheic keratoses, dermatofibroma, keloids, molluscum contagiosum, and benign nevi" Order ALL the reference details at left...
2.	Drug Therapy (Chemotherapy) 01/01/2006 - "In the subset of fibrous histiocytomas that invade bone, however adjunctive treatment with radiation and or chemotherapy may be appropriate." 12/01/1982 - "Inflammatory fibrous histiocytoma: an important variant of malignant fibrous histiocytoma highly responsive to chemotherapy." 12/01/1980 - "A metastasizing fibrous histiocytoma arising in the lung of a patient who received radiation therapy and long-term chemotherapy for malignant lymphoma is presented" 01/15/2000 - "Several of the patients developed treatment-related sequelae, including veno-occlusive disease of the lung and hemorrhagic cystitis (1), myelodysplastic syndrome (1), chemotherapy-induced ovarian failure (1), moist desquamation (1), and dermatofibroma within the radiotherapy volumes (1)" 07/20/2001 - "This study sought to use a microdialysis technique to relate clinical and biochemical responses to the time course of melphalan concentrations in the subcutaneous interstitial space and in tumour tissue (melanoma, malignant fibrous histiocytoma, Merkel cell tumour and osteosarcoma) in patients undergoing regional chemotherapy by Isolated Limb Infusion (ILI)" Order ALL the reference details at left...
3.	Mohs Surgery (Mohs' Micrographic Surgery) 02/01/2004 - "Treatment of dermatofibroma protuberans with fixed Mohs' micrographic surgery]" 06/01/2008 - "OBJECTIVES: The purpose of this study was to evaluate the use of modified Mohs micrographic surgery (MMS) for dermatofibroma sarcoma protuberans (DFSP) in a single institution by a single surgeon" 06/01/2008 - "Treatment of dermatofibroma sarcoma protuberans using modified Mohs micrographic surgery: no recurrences and smaller defects." Order ALL the reference details at left...
4.	Gas Lasers 05/01/2007 - "Multiple dermatofibromas on face treated with carbon dioxide laser." 03/01/2008 - "Multiple dermatofibromas on face treated with carbon dioxide laser: the importance of laser parameters." Order ALL the reference details at left...
5.	Pneumonectomy (Lung Volume Reduction) 04/01/2002 - "Unilateral progressive multiple sclerosing hemangioma in a young female successfully treated by pneumonectomy: report of a case." 09/01/1987 - "A child had a pulmonary plasma cell granuloma/fibrous histiocytoma that recurred after lobectomy in 1952 and required pneumonectomy in 1953, at which time it extended into the mediastinum at the pulmonary hilus" Order ALL the reference details at left...