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Mesenchymal Chondrosarcoma

A rare aggressive variant of chondrosarcoma, characterized by a biphasic histologic pattern of small compact cells intermixed with islands of cartilaginous matrix. Mesenchymal chondrosarcomas have a predilection for flat bones; long tubular bones are rarely affected. They tend to occur in the younger age group and are highly metastatic. (DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1456)
Also Known As:
Chondrosarcoma, Mesenchymal; Chondrosarcomas, Mesenchymal; Mesenchymal Chondrosarcomas
Networked: 63 relevant articles (3 outcomes, 6 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Chondrosarcoma
2. Neoplasm Metastasis (Metastasis)
3. Neoplasms (Cancer)
4. Osteosarcoma (Osteogenic Sarcoma)
5. Sarcoma (Soft Tissue Sarcoma)

Experts

1. Hogendoorn, Pancras C W: 2 articles (02/2012 - 03/2008)
2. Fanburg-Smith, Julie C: 2 articles (05/2010 - 02/2010)
3. Wang, Zengfeng: 2 articles (05/2010 - 02/2010)
4. Rushing, Elisabeth J: 2 articles (05/2010 - 02/2010)
5. Auerbach, Aaron: 2 articles (05/2010 - 02/2010)
6. Marwaha, Jayson S: 2 articles (05/2010 - 02/2010)
7. Odronic, Shelley I: 1 article (06/2015)
8. Springer, Bridgette S: 1 article (06/2015)
9. Smith, Amber L: 1 article (06/2015)
10. Reynolds, Jordan P: 1 article (06/2015)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Mesenchymal Chondrosarcoma:
1. bevacizumabFDA Link
2. docetaxel (Taxotere)FDA Link
3. S100 Proteins (S 100 Protein)IBA
4. VimentinIBA
5. Matrix Metalloproteinase 14 (MT1-MMP)IBA
6. Collagen Type II (Type II Collagen)IBA
7. Tissue Inhibitor of Metalloproteinase-2IBA
8. Proteins (Proteins, Gene)IBA
9. AntibodiesIBA
10. N 30IBA

Therapies and Procedures

1. Drug Therapy (Chemotherapy)
2. Radiotherapy
3. Nephrectomy
4. Adjuvant Chemotherapy
5. Transplantation (Transplant Recipients)