Pulmonary Blastoma

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48 relevant articles (6 outcomes, 3 trials/studies) found for this Disease

Description: A malignant neoplasm of the lung composed chiefly or entirely of immature undifferentiated cells (i.e., blast forms) with little or virtually no stroma. (From Stedman, 25th ed)

Also Known As:

Blastomas, Pulmonary; Pulmonary Blastomas; Blastoma, Pulmonary

Relationship Network

Disease Context: Research Results

Neoplasms: 386513

Neoplasms by Histologic Type: 1

Complex and Mixed Neoplasms

Pulmonary Blastoma: 48

Neoplasms by Site: 1

Thoracic Neoplasms: 16

Respiratory Tract Neoplasms: 7

Lung Neoplasms: 18439

Pulmonary Blastoma: 48

Related Diseases

1.	Neoplasms (Cancer)
2.	Carcinosarcoma
3.	Carcinoma (Carcinomatosis)
4.	Rhabdomyosarcoma
5.	Neuroblastoma
19 Diseases and 24 more articles analyzed in the Research Interface, order at left...

Experts

1.	Truskinovsky, Alexander M: 1 article (04/2007)
2.	Dudek, Arkadiusz Z: 1 article (04/2007)
3.	Mulamalla, Keerthi: 1 article (04/2007)
4.	Sakamoto, Kazuhiro: 1 article (07/2004)
5.	Inayama, Yoshiaki: 1 article (07/2004)
6.	Nozawa, Akinori: 1 article (07/2004)
7.	Ogawa, Nobuo: 1 article (07/2004)
8.	Oka, Teruaki: 1 article (07/2004)
9.	Koss, Michael N: 1 article (07/2004)
10.	Mark, Eugene J: 1 article (07/2004)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Pulmonary Blastoma:

1.	GalliumIBA 02/01/1993 - "A case of a 7-year-old girl with pulmonary blastoma is reported in which the primary tumor is extremely Ga-67-avid and in which the gallium scans were helpful in determining early recurrence and metastatic disease to the brain." Get all the results and reference details, order at left...
2.	Keratins (Keratin)IBA 12/01/1985 - "In all four pulmonary blastomas and in five of nine carcinosarcomas, the sarcomatous elements failed to stain for keratin but in the remaining four carcinosarcomas there was focal staining" 12/01/1985 - "Pulmonary blastoma, carcinosarcoma and spindle-cell carcinoma: an immunohistochemical study of keratin intermediate filaments." 06/01/1988 - "The immunohistochemical staining patterns of three pulmonary blastomas (PBs) were studied for markers of mesenchymal (vimentin, muscle-specific actin) and epithelial (cytokeratin, epithelial membrane antigen) differentiation to clarify their phenotypic nature and, possibly, their histogenesis" 03/01/1989 - "Three cases of pulmonary blastoma (PB) were investigated microscopically with conventional stainings and immunohistochemically with monoclonal antibodies to cytokeratin, vimentin, desmin and neurofilament protein" Get all the results and reference details, order at left...
3.	AntigensIBA 01/01/1995 - "Among the non-epithelial tumors investigated, those antigens were detected in pulmonary blastomas but not in mesotheliomas" 01/01/1991 - "In order to investigate the probable embryonic nature of pulmonary blastoma, immunohistochemical studies were performed using stage-specific embryonic antigens (Ley, Lex, sialyl Lex-i) in case of pulmonary blastoma with a very wide spectrum of morphological features" Get all the results and reference details, order at left...
4.	sorafenib (BAY 43-9006)FDA Link 04/01/2007 - "We believe that further studies are warranted to confirm the possible effects of sorafenib on pulmonary blastomas." 04/01/2007 - "We report a rare case of renal metastasis of biphasic pulmonary blastoma that responded to sorafenib, an oral multikinase inhibitor" 04/01/2007 - "Pulmonary blastoma with renal metastasis responds to sorafenib." Get all the results and reference details, order at left...
5.	5- acetylneuraminyl- (2- 3)- galactosyl- (1- 4)- (fucopyranosyl- (1- 3))- N- acetylglucosamine (sialyl Lewis x)IBA 01/01/1991 - "In order to investigate the probable embryonic nature of pulmonary blastoma, immunohistochemical studies were performed using stage-specific embryonic antigens (Ley, Lex, sialyl Lex-i) in case of pulmonary blastoma with a very wide spectrum of morphological features" Get all the results and reference details, order at left...
6.	alpha-Fetoproteins (AFP)IBA 12/01/1992 - "The epithelial cells of pulmonary blastomas may occasionally de-differentiate into cells functionally resembling fetal hepatic, foregut and yolk sac cells expressing AFP" 05/01/1998 - "Alpha-fetoprotein producing pulmonary blastoma in a patient with systemic sclerosis: pathogenetic analysis." 09/01/1991 - "We describe the clinical and pathologic features of two cases of pulmonary blastoma having alpha-fetoprotein production and histologic areas of yolk sac tumor" 05/01/1989 - "A 75-year-old male case of a pulmonary blastoma with high serum alpha-fetoprotein (AFP) and carcinoembryonic antigen (CEA) levels is reported" 05/01/1989 - "An autopsied case of pulmonary blastoma with high serum alpha-fetoprotein and carcinoembryonic antigen levels]" Get all the results and reference details, order at left...
7.	beta CateninIBA 06/01/2003 - "Beta-catenin mutations in pulmonary blastomas: association with morule formation." 07/01/2007 - "To understand the molecular process of histogenesis of this tumor, a whole genome allelic imbalance (AI) scanning using a high-resolution single nucleotide polymorphism array as well as mutational analysis of the p53, EGFR, KRAS and beta-catenin genes were performed against the epithelial and mesenchymal components in the primary tumor and a metastatic tumor in a case of pulmonary blastoma" 07/01/2004 - "We recently demonstrated that low-grade adenocarcinoma of the fetal lung type (L-FLAC)/well-differentiated fetal adenocarcinoma (WDFA), the epithelial prototype of classic pulmonary blastoma (CPB), shows N/C localization of beta-catenin with genetic mutation" 07/01/2004 - "Aberrant nuclear/cytoplasmic localization and gene mutation of beta-catenin in classic pulmonary blastoma: beta-catenin immunostaining is useful for distinguishing between classic pulmonary blastoma and a blastomatoid variant of carcinosarcoma." 06/01/2003 - "To elucidate the contribution of beta-catenin gene mutation to the development of pulmonary blastomas, we analysed mutations in three well-differentiated fetal adenocarcinomas (WDFAs) and six biphasic pulmonary blastomas (BPBs)" Get all the results and reference details, order at left...
8.	VimentinIBA 06/01/1988 - "The immunohistochemical staining patterns of three pulmonary blastomas (PBs) were studied for markers of mesenchymal (vimentin, muscle-specific actin) and epithelial (cytokeratin, epithelial membrane antigen) differentiation to clarify their phenotypic nature and, possibly, their histogenesis" 01/01/1988 - "We report two cases of pulmonary blastoma with rhabdomyoblastic differentiation documented for the first time by electron microscopy and immunohistochemistry including documentation for myoglobin, actin, vimentin and desmin" 03/01/1989 - "Three cases of pulmonary blastoma (PB) were investigated microscopically with conventional stainings and immunohistochemically with monoclonal antibodies to cytokeratin, vimentin, desmin and neurofilament protein" Get all the results and reference details, order at left...
9.	Monoclonal AntibodiesIBA 01/01/1998 - "5 microns frozen sections from 15 nephroblastomas, 13 neuroblastomas, six rhabdomyosarcomas, one Ewing sarcoma and one pulmonary blastoma were analyzed by the alkaline phosphatase anti-alkaline phosphatase (APAAP) method using murine monoclonal antibodies" 02/01/1990 - "The reaction pattern found in thirteen different pulmonary blastomas was tested with four different polyclonal and six different monoclonal antibodies using the avidin-biotin-reaction" 03/01/1989 - "Three cases of pulmonary blastoma (PB) were investigated microscopically with conventional stainings and immunohistochemically with monoclonal antibodies to cytokeratin, vimentin, desmin and neurofilament protein" Get all the results and reference details, order at left...
10.	AntibodiesIBA 11/01/1991 - "Persistent polyclonal B lymphocytosis with Epstein-Barr virus antibodies and subsequent malignant pulmonary blastoma." 04/01/1991 - "Persistent polyclonal B lymphocytosis with Epstein-Barr virus antibodies and subsequent malignant pulmonary blastoma." 02/01/1984 - "Tumor cells of different carcinomas, thymomas, and the epithelial part of pulmonary blastomas were positive with antibodies recognizing cytokeratins" Get all the results and reference details, order at left...
26 Drugs and Important Bio-Agents and 29 more articles analyzed in the Research Interface, order at left...

Therapies and Procedures

1.	Drug Therapy (Chemotherapy) 12/01/1995 - "The case is reported of a 2-year-old boy with pleuro-pulmonary blastoma who achieved partial remission with conventional chemotherapy and surgery" 02/01/1998 - "Pulmonary blastoma: case report of a patient with a 7-year remission and review of chemotherapy experience in the world literature." 07/01/1984 - "Pulmonary blastoma: remission with chemotherapy." 01/01/1997 - "Uncertain role of high dose chemotherapy with autologous stem cell support in pediatric pleuro-pulmonary blastoma (PPB)" 03/01/1996 - "Case report: pulmonary blastoma in children--response to chemotherapy." Get all the results and reference details, order at left...
2.	Combination Drug Therapy (Combination Chemotherapy) 08/01/1994 - "Our observation suggest that this intensive combination chemotherapy is effective in recurrent and metastatic disease of pulmonary blastoma as a surgical adjuvant." 01/01/1982 - "We report a case of metastatic pulmonary blastoma that had a partial remission with combination chemotherapy" Get all the results and reference details, order at left...
3.	Adjuvant Chemotherapy 02/01/1998 - "The world literature was reviewed with regard to the use of adjuvant chemotherapy in the treatment of pulmonary blastoma" 08/01/1996 - "Resection and adjuvant chemotherapy of pulmonary blastoma" 08/01/1996 - "Resection and adjuvant chemotherapy of pulmonary blastoma" 11/01/1995 - "Resection and adjuvant chemotherapy of pulmonary blastoma: a case report." 03/01/2002 - "We report a case of biphasic pulmonary blastoma in an adult male who underwent liver transplant for hepatocellular carcinoma in March 1999, followed by immunosuppressive treatment and adjuvant chemotherapy with epirubicin" Get all the results and reference details, order at left...
4.	Pneumonectomy (Lung Volume Reduction) 11/01/1986 - "Left sleeve pneumonectomy of a patient with pulmonary blastoma required for stump recurrence after left upper lobectomy]" 07/01/1984 - "A 59-year-old man with pulmonary blastoma, who had undergone right-sided pneumonectomy, had a relapse of the tumour 7 months later" 12/01/1995 - "The tumor was diagnosed as pulmonary blastoma as a result of echographic biopsy, and right total pneumonectomy was performed" Get all the results and reference details, order at left...
5.	Transplants (Transplant) 03/01/2002 - "To our knowledge this is the first reported case of pulmonary blastoma in a transplant patient" 03/01/2002 - "Pulmonary blastoma after liver transplant: a case report." 03/01/2002 - "Our findings confirm that organ transplant recipients deserve long-term medical surveillance also in the absence of graft complications, and that pulmonary blastoma is an aggressive tumor with a poor prognosis." 03/01/2002 - "We report a case of biphasic pulmonary blastoma in an adult male who underwent liver transplant for hepatocellular carcinoma in March 1999, followed by immunosuppressive treatment and adjuvant chemotherapy with epirubicin" Get all the results and reference details, order at left...
8 Therapies and Procedures and 20 more articles analyzed in the Research Interface, order at left...

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