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CD80 Antigens

The natural ligand for the T-cell antigen CD28; (ANTIGENS, CD28); mediating T- and B-cell adhesion. CD80 is expressed on activated B-cells and gamma-interferon-stimulated monocytes. The binding of CD80 to CD28 and CTLA-4 provides a co-stimulatory signal to T-cells and leads to greatly upregulated lymphokine production.
Also Known As:
Antigens, CD80; Antigen, B7; Antigen, B7-1; B7 Antigen; B7-1 Antigen; CD80 Antigen; Antigen, B7 1; B Cell Activation Antigen; B7 1 Antigen; B7 1 Costimulatory Molecule; Costimulatory Molecule, B7-1; B-Cell Activation Antigen; B7-1 Costimulatory Molecule
Networked: 59 relevant articles (2 outcomes, 5 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Wang, J: 2 articles (10/2000 - 03/2000)
2. Djamali, Arjang: 1 article (09/2015)
3. Redfield, Robert R: 1 article (09/2015)
4. Huang, Gengwen: 1 article (09/2015)
5. Zhong, Weixiong: 1 article (09/2015)
6. Reese, Shannon R: 1 article (09/2015)
7. Wilson, Nancy A: 1 article (09/2015)
8. Doesch, Andreas O: 1 article (01/2014)
9. Rohde, David: 1 article (01/2014)
10. Erbel, Christian: 1 article (01/2014)

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4. Vaccinia
5. Infection

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5. aniline (aniline hydrobromide)
6. Antigens
7. Interleukin-12 (IL 12)
8. Interferon-gamma (Interferon, gamma)
9. Interleukin-2 (IL2)
10. Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)

Related Therapies and Procedures

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2. Immunotherapy