HOMEPRODUCTSSERVICESCOMPANYCONTACTFAQResearchDictionaryPharmaMobileSign Up FREE or Login

Multidrug-Resistant Tuberculosis (Drug-Resistant Tuberculosis)

Tuberculosis resistant to chemotherapy with two or more ANTITUBERCULAR AGENTS, including at least ISONIAZID and RIFAMPICIN. The problem of resistance is particularly troublesome in tuberculous OPPORTUNISTIC INFECTIONS associated with HIV INFECTIONS. It requires the use of second line drugs which are more toxic than the first line regimens. TB with isolates that have developed further resistance to at least three of the six classes of second line drugs is defined as EXTENSIVELY DRUG-RESISTANT TUBERCULOSIS.
Also Known As:
Drug-Resistant Tuberculosis; Multi-Drug Resistant Tuberculosis; Tuberculosis, Multi-Drug Resistant; Tuberculosis, Multidrug Resistant; Tuberculosis, Multidrug-Resistant; Tuberculosis, MDR; MDR Tuberculosis; Tuberculosis, Drug Resistant; Tuberculosis, Multi Drug Resistant; Tuberculosis, Drug-Resistant
Networked: 866 relevant articles (41 outcomes, 73 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Tuberculosis (Tuberculoses)
2. Infection
3. Acquired Immunodeficiency Syndrome (AIDS)
4. Extensively Drug-Resistant Tuberculosis
5. Pulmonary Tuberculosis

Experts

1. Isaakidis, Petros: 9 articles (12/2015 - 01/2013)
2. Zumla, Alimuddin: 9 articles (05/2015 - 05/2010)
3. Cho, Sang-Nae: 9 articles (03/2014 - 09/2007)
4. Amaral, Leonard: 9 articles (12/2013 - 09/2005)
5. Via, Laura E: 8 articles (12/2015 - 01/2010)
6. Barry, Clifton E: 8 articles (03/2014 - 01/2010)
7. Alffenaar, Jan-Willem C: 7 articles (10/2015 - 02/2010)
8. van der Werf, Tjip S: 7 articles (10/2015 - 02/2010)
9. Yew, Wing Wai: 7 articles (04/2015 - 10/2003)
10. Viveiros, Miguel: 7 articles (01/2015 - 09/2005)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Multidrug-Resistant Tuberculosis:
1. Ofloxacin (Levofloxacin)FDA LinkGeneric
2. Isoniazid (Ftivazide)FDA LinkGeneric
3. Rifampin (Rifampicin)FDA LinkGeneric
4. Thioridazine (Mellaril)FDA LinkGeneric
5. linezolid (Zyvox)FDA Link
6. Carbon MonoxideIBA
7. AntigensIBA
8. butyl 3-(1H-tetrazol-5-yl)oxanilate (MTB)IBA
9. moxifloxacin (Avelox)FDA Link
10. Ethionamide (Trecator-SC)FDA Link

Therapies and Procedures

1. Drug Therapy (Chemotherapy)
2. Retreatment
3. Highly Active Antiretroviral Therapy (HAART)
4. Chemoprevention
5. Therapeutics