|5.||Hearing Loss (Hearing Impairment)
|1.||Saliba, Issam: 4 articles (08/2015 - 02/2011)|
|2.||Shen, Yi: 4 articles (08/2015 - 01/2012)|
|3.||Hosemann, W: 4 articles (12/2006 - 08/2004)|
|4.||Kaftan, H: 4 articles (12/2006 - 08/2004)|
|5.||von Unge, Magnus: 3 articles (08/2015 - 07/2007)|
|6.||Dilley, Rodney J: 3 articles (08/2015 - 01/2014)|
|7.||Atlas, Marcus D: 3 articles (08/2015 - 01/2012)|
|8.||Hultcrantz, Malou: 3 articles (05/2011 - 07/2007)|
|9.||Park, Seong Kook: 3 articles (07/2009 - 04/2004)|
|10.||Oh, Seung-Ha: 2 articles (12/2015 - 11/2004)|
|1.||Thymidine Monophosphate (TMP)IBA
10/01/2015 - "This study aimed to evaluate the potential association between single nucleotide polymorphisms (SNPs) in selected genes and rAOM and to analyze whether genetic variations might predispose to the development of complicated recurrent cases, such as those with tympanic membrane perforation (TMP).A total of 33 candidate genes and 47 SNPs were genotyped in 200 children with rAOM (116 with a history of TMP) and in 200 healthy controls.INFγ rs 12369470CT was significantly less common in the children with rAOM than in healthy controls (odds ratio [OR] 0.5, 95% confidence interval [CI] 0.25-1, P = 0.04). "
11/01/2011 - "Though it is safe for external ear use, no study has proven its safety in cases of tympanic membrane perforation (TMP). "
05/01/2014 - "Does phone multimedia messages (MMS) to families of Indigenous children with tympanic membrane perforation (TMP): (i) increase clinic attendance; (ii) improve ear health; and (iii) provide a culturally appropriate method of health promotion? "
07/08/2013 - "To measure the impact of 4 weeks of daily swimming on rates of ear discharge among Aboriginal children with a tympanic membrane perforation (TMP) and on the microbiology of the nasopharynx and middle ear. "
10/01/2011 - "To establish a tissue engineering therapy for the treatment of large tympanic membrane perforation (TMP) without the need for conventional surgical therapy. "
10/01/2015 - "The silicone flowed into the middle ear through a tympanic membrane perforation during the process of making an ear mold. "
08/01/2003 - "The study demonstrated that bFGF combined with an atelocollagen/silicone bilayer membrane is effective for the conservative treatment of tympanic membrane perforation."
|5.||Ofloxacin (Levofloxacin)FDA LinkGeneric
01/01/2001 - "Because a number of cases of otitis externa are complicated by an undiagnosed tympanic membrane perforation, the lack of ototoxicity associated with ofloxacin otic makes it a particularly safe option for use in these patients."
10/01/2007 - "Effects of ciprofloxacin/dexamethasone and ofloxacin on tympanic membrane perforation healing."
|7.||Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA
03/01/1993 - "Histological study of the healing of traumatic tympanic membrane perforation after basic fibroblast growth factor application."
10/01/2014 - "Effects of basic fibroblast growth factor dose on traumatic tympanic membrane perforation."
07/01/1993 - "Direct application of basic fibroblast growth factor improves tympanic membrane perforation healing."
01/01/1995 - "The beneficial effects of basic fibroblast growth factor (bFGF or FGF-2) in healing of tympanic membrane (TM) perforations have been demonstrated in animal models, and this study was conducted to investigate the effect of neutralizing anti-FGF-2 antibodies on acute tympanic membrane perforation healing. "
03/01/2015 - "A pilot study to investigate the utility of basic Fibroblast Growth Factor (bFGF) in tympanic membrane perforation (TMP) closure in a small cohort of pediatric patients. "
|8.||Dexamethasone (Maxidex)FDA LinkGeneric
04/01/2010 - "Topical dexamethasone and tympanic membrane perforation healing in otitis media: a short-term study."
04/01/2011 - "In this article, we discuss a group of 11 patients with sensorineural hearing loss who underwent myringotomy and tube placement for home-based dexamethasone instillation and subsequently developed the complication of tympanic membrane perforation. "
09/01/2010 - "We report the case of a female patient suffering from intractable otitis externa with tympanic membrane perforation, who was successfully treated locally with a mixture of 1% NCT and 0.1% dexamethasone."
09/01/2005 - "The purpose of this study was to determine whether systemic glucocorticoid application, in combination with topical mitomycin or dexamethasone, prolongs the patency of a tympanic membrane perforation. "
08/01/2015 - "Searching for a rat model of chronic tympanic membrane perforation: Healing delayed by mitomycin C/dexamethasone but not paper implantation or iterative myringotomy."
06/01/2015 - "In this study, we investigated the treatment effects of the silk patch in patients with traumatic tympanic membrane perforation (TTMP). "
06/01/2015 - "We therefore believe that the silk patch should be recommended for the treatment of acute tympanic membrane perforation."
06/01/2015 - "Clinical outcomes of silk patch in acute tympanic membrane perforation."
02/01/2014 - "Recent experimental studies have shown the suitability of silk fibroin scaffold (SFS) and porcine-derived acellular collagen I/III scaffold (ACS) as onlay graft materials for tympanic membrane perforation repair. "
|10.||Hyaluronic Acid (Hyaluronan)IBA
01/01/1992 - "In experimental animal studies, exogenous hyaluronan (HA) has been shown to exert beneficial effects on the healing of tympanic membrane perforation. "
01/01/2012 - "Hyaluronic acid has been found to accelerate tympanic membrane perforation closure, shorten the period of healing, produce a better quality neo-membrane and improve hearing. "
01/01/2012 - "Recently, there has been an increased interest in hyaluronic-acid-related research and products as a potential therapeutic option for tympanic membrane perforation repair. "
12/01/2006 - "Our results support the proposition that hyaluronic acid (HA) provides a moist wound-healing environment to aid in the healing process of tympanic membrane perforation. "
07/01/2006 - "Repair of tympanic membrane perforation by topical application of 1% sodium hyaluronate."
06/01/2015 - "This study focuses on the influence of size and site of tympanic membrane perforation on success rate of Myringoplasty. "
08/01/2001 - "One group of subjects had a tympanic membrane perforation and was recruited to the study before admission for myringoplasty. "
11/01/2015 - "To evaluate the results of a newly introduced technique to our Department of endoscopic assisted transcanal myringoplasty applied in tympanic membrane perforation in children of any age and compare them to that of the previously standard microscopic assisted myringoplasty technique. "
10/01/2014 - "Myringoplasty using rotation flap of canal skin for total tympanic membrane perforation."
04/01/2013 - "It was feasible and safe to perform bilateral same-day myringoplasty for bilateral tympanic membrane perforation, but the postoperative temporary discomfort of bilateral ear fullness should be informed the patients in advance."
09/01/2014 - "Study of outcome of tympanoplasties in relation to size and site of tympanic membrane perforation."
11/01/2012 - "This study included 114 patients without postoperative tympanic membrane perforation who underwent tympanoplasty type I between 2007 and 2010, 31 with fascia and 83 with cartilage. "
01/01/2012 - "The study included primary tympanoplasty cases with a subtotal perforation, an intact ossicular chain, a dry ear for at least one month and normal middle-ear mucosa, together with contralateral tympanic membrane perforation. "
02/01/2011 - "This study shows that tympanoplasty is a valid treatment modality for tympanic membrane perforation in the pediatric population. "
10/01/2001 - "This study was designed to identify the external ear resonance characteristics of patients with tympanic membrane perforation and to investigate subsequent changes in external ear resonance, depending on the length of the postoperative period and which of 3 different types of operation was performed: tympanoplasty with canal wall-up mastoidectomy, epitympanoplasty, and canal wall-down mastoidectomy. "
03/01/2004 - "The pieces of graft material under study were removed after 5 days, leaving the graft used to seal the tympanic membrane perforation undisturbed. "
05/31/2001 - "Thirty patients were included in this study over a period of 2 years, where cartilage perichondrium composite graft (CPCG) was used to close the tympanic membrane perforation. "
01/01/2013 - "In our technique, an inferior rather than a posterior flap is raised and the graft is laid from the inferior direction to obtain better access to the anterior part of the tympanic membrane perforation and provide better support. "
01/01/2013 - "We concluded that 0.2 mm partial thickness cartilage graft is optimal in reconstruction of subtotal tympanic membrane perforation because it is excellent to obtain high take rate with good hearing results."
11/01/2006 - "Repair of tympanic membrane perforation using a modified cartilage-perichondrium composite ring graft."
|4.||Absorbable Gelatin Sponge
10/01/2011 - "As compared with spontaneous healing, FGF-containing gelfoam patching had an improved outcome in children with edge-everted traumatic eardrum perforation. "
08/01/2011 - "Re: A randomised controlled trial comparing spontaneous healing, gelfoam patching, and edge-approximation plus gelfoam patching in traumatic tympanic membrane perforation with in-/everted edges."
06/01/2011 - "A randomised controlled trial comparing spontaneous healing, gelfoam patching and edge-approximation plus gelfoam patching in traumatic tympanic membrane perforation with inverted or everted edges."
08/01/2015 - "The perforation margin phenotypes and clinical outcome of traumatic tympanic membrane perforation with a Gelfoam patch: our experience from a retrospective study of seventy-four patients."
06/01/2011 - "To compare the outcome of patients with dry traumatic tympanic membrane perforation after spontaneous healing and gelfoam patching with or without perforation edge approximation. "
|5.||Middle Ear Ventilation (Tympanostomy)
07/01/2012 - "Long-lasting dry eardrum perforation allows for adequate middle ear ventilation and drainage and guarantees sustained relief from symptoms. "
07/01/2015 - "Pediatric Tympanostomy Tube Removal Technique and Effect on Rate of Persistent Tympanic Membrane Perforation."
09/01/2010 - "Records were evaluated for 82 children with dry tympanic membrane perforation (any size) and intact ossicular chain, and with no history of previous ear surgery except for tympanostomy. "
03/01/2000 - "The models combine measurement-based Thévenin equivalents for insert and supra-aural earphones with lumped-element models for both the normal ear and ears with pathologies that alter the ear's impedance (mastoid bowl, tympanostomy tube, tympanic-membrane perforation, and a "high-impedance" ear). "
11/01/1992 - "The reported incidence of persistent tympanic membrane perforation after the extrusion or removal of Goode-type tympanostomy tubes varies from 3 per cent to 47.5 per cent. "