|1.||Haley, Gwendolen E: 3 articles (08/2010 - 08/2007)|
|2.||Dawson, Lee A: 3 articles (02/2010 - 01/2008)|
|3.||Lessard, Andrée: 3 articles (06/2009 - 02/2003)|
|4.||Spooren, Will: 3 articles (12/2008 - 12/2005)|
|5.||Advenier, C: 3 articles (12/2001 - 11/2000)|
|6.||Lessard, A: 2 articles (09/2013 - 02/2012)|
|7.||Misono, K: 2 articles (09/2013 - 02/2012)|
|8.||Malherbe, Pari: 2 articles (05/2011 - 06/2008)|
|9.||Smith, Paul W: 2 articles (02/2010 - 01/2008)|
|10.||de la Flor, Raúl: 2 articles (02/2010 - 02/2009)|
|1.||Schizophrenia (Dementia Praecox)
04/01/2014 - "This study investigates the efficacy, tolerability, and cognitive effects of AZD2624, a selective, orally active NK(3) receptor antagonist, in symptomatic patients with schizophrenia. "
05/01/2011 - "The neurokinin 3 (NK(3)) receptor is a GPCR that has been shown to modulate monoaminergic systems within regions of the brain implicated in schizophrenia. "
07/01/2010 - "Novel NK(3) receptor antagonists for the treatment of schizophrenia and other CNS indications."
02/01/2009 - "Neurokinin-3 (NK(3)) receptor distribution and its modulatory influence on dopaminergic and noradrenergic neurotransmission have lead to the hypothesis that NK(3) receptor antagonists may be a valid target to ameliorate the symptomatology of schizophrenia. "
06/01/2008 - "The neurokinin 3 (NK(3)) receptor is a novel target under investigation for improvement of the symptoms of schizophrenia due to its ability to modulate dopaminergic signaling. "
01/01/2000 - "The present study determined whether the second most abundant class of neurokinin receptors, neurokinin(3) receptors, are regulated during persistent peripheral inflammation. "
01/01/2000 - "The change in neurokinin(3) receptor binding and messenger RNA during adjuvant-induced inflammation may be a consequence of activation of the receptor. "
01/01/2000 - "Time-dependent changes in neurokinin(3) receptors and tachykinins during adjuvant-induced peripheral inflammation in the rat."
10/19/2001 - "Preclinical studies have indicated a role for the tachykinin NK(1), NK(2) and NK(3) receptors in bronchoconstriction, airway hyperresponsiveness and airway inflammation caused by allergic and nonallergic stimuli. "
01/01/1999 - "Central and peripheral expression of neurokinin-1 and neurokinin-3 receptor and substance P-encoding messenger RNAs: peripheral regulation during formalin-induced inflammation and lack of neurokinin receptor expression in primary afferent sensory neurons."
|3.||Ganglion Cysts (Ganglion)
05/01/1998 - "In this study, the generation mechanism of NK-3 receptor agonist-induced response in the hamster submandibular ganglion (SMG) cells was investigated using the current-clamp technique. "
06/01/1999 - "Thus, NK-1 and NK-3 receptors are apparently coupled with non-selective cation channels in submandibular ganglion cells."
01/01/1999 - "It is suggests that tachykinin NK-3 receptors take part in SP-ergic synaptic transmission through the rat's caudal mesenteric ganglion."
05/01/1998 - "Tachykinin-depolarizations mediated by neurokinin-3 receptors in the hamster submandibular ganglion cells."
01/01/1999 - "Effects of tachykinin NK-3 receptors antagonist SR 142801 on the synaptic transmission in the rat's caudal mesenteric ganglion were investigated using extracellular recording of compound action potentials (CAPs) from the ganglion nerves. "
08/01/2002 - "This study was designed to provide evidence for elucidating the mechanisms of neurokinin-3 receptor (NK3) in spinal pain modulation. "
05/01/1999 - "Neurokinin 3 receptors in the gut: a new target for the treatment of visceral pain?"
10/01/1998 - "Antagonists at NK-3 receptors might help controlling pain transmission."
|5.||Hypogonadism (Hypergonadotropic Hypogonadism)
03/01/2013 - "Genetic studies in human patients with idiopathic hypogonadotropic hypogonadism (IHH) identified mutations in the genes that encode neurokinin B (NKB) and the neurokinin 3 receptor (NK3R). "
08/01/2010 - "Recent data have demonstrated that mutations in the receptor for neurokinin B (NKB), the NK-3 receptor (NK3R), produce hypogonadotropic hypogonadism in humans. "
11/01/2013 - "Mutations in neurokinin B (NKB) or the neurokinin-3 receptor (NK3R) are linked to hypogonadotropic hypogonadism in humans, suggesting that NKB may regulate GnRH secretion. "
|1.||SR 142801 (osanetant)
|7.||Neurokinin-1 Receptors (Neurokinin 1 Receptor)
|8.||NK 2 (NK-2)
|9.||Messenger RNA (mRNA)