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Leukotriene D4

One of the biologically active principles of SRS-A. It is generated from LEUKOTRIENE C4 after partial hydrolysis of the peptide chain, i.e., cleavage of the gamma-glutamyl portion. Its biological actions include stimulation of vascular and nonvascular smooth muscle, and increases in vascular permeability. (From Dictionary of Prostaglandins and Related Compounds, 1990)
Also Known As:
Leukotriene D; Leukotriene D-4; Leukotrienes D; Leukotriene D 4; LTD4; Glycine, N-(S-(1-(4-carboxy-1-hydroxybutyl)-2,4,6,9-pentadecatetraenyl)-L-cysteinyl)-, (R-(R*,S*-(E,E,Z,Z)))-
Networked: 437 relevant articles (16 outcomes, 40 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Sjölander, Anita: 9 articles (11/2015 - 10/2003)
2. Gao, Yi: 5 articles (01/2015 - 05/2012)
3. Mizutani, Nobuaki: 4 articles (11/2015 - 01/2003)
4. Shi, Xu: 4 articles (01/2015 - 06/2013)
5. Kanaoka, Yoshihide: 4 articles (12/2013 - 08/2007)
6. Nabe, T: 4 articles (01/2009 - 06/2001)
7. Kohno, S: 4 articles (01/2009 - 06/2001)
8. Mizutani, N: 4 articles (01/2009 - 06/2001)
9. Nabe, Takeshi: 3 articles (11/2015 - 08/2003)
10. Zhu, Zheng: 3 articles (01/2015 - 06/2013)

Related Diseases

1. Asthma (Bronchial Asthma)
2. Hypersensitivity (Allergy)
3. Ischemia
4. Acute Kidney Injury (Acute Renal Failure)
5. Traumatic Shock

Related Drugs and Biologics

1. Leukotriene C4
2. montelukast (Singulair)
3. Leukotriene D4
4. Leukotriene E4
5. Leukotriene B4
6. leukotriene D4 receptor (cysteinyl leukotriene receptor)
7. zafirlukast (Accolate)
8. Arachidonate 5-Lipoxygenase (5 Lipoxygenase)
9. Methacholine Chloride (Methacholine)
10. verlukast

Related Therapies and Procedures

1. Tourniquets
2. Intra-Arterial Infusions
3. Injections
4. Warm Ischemia
5. Heterologous Transplantation (Xenotransplantation)