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Neurotransmitter Receptors (Neurotransmitter Receptor)

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Cell surface receptors that bind signalling molecules released by neurons and convert these signals into intracellular changes influencing the behavior of cells. Neurotransmitter is used here in its most general sense, including not only messengers that act to regulate ion channels, but also those which act on second messenger systems and those which may act at a distance from their release sites. Included are receptors for neuromodulators, neuroregulators, neuromediators, and neurohumors, whether or not located at synapses.

Also Known As:

Neurotransmitter Receptor; Receptors, Neurotransmitter; Neuromediator Receptor; Neuromodulator Receptor; Neuroregulator Receptor; Receptors, Neuromediators; Receptors, Neuromodulators; Receptors, Neuroregulators; Receptors, Neurotransmitters; Neuromediators Receptors; Neuromodulators Receptors; Neuroregulators Receptors; Neurotransmitters Receptors; Receptor, Neuromediator; Receptor, Neuromodulator; Receptor, Neuroregulator; Receptor, Neurotransmitter; Receptors, Neuromediator; Receptors, Neuromodulator; Receptors, Neuroregulator; Neurohumor Receptors; Neuromediator Receptors; Neuromodulator Receptors; Neuroregulator Receptors; Receptors, Neurohumor; Receptors, Synaptic; Synaptic Receptors

Networked: 277 relevant articles (4 outcomes, 35 trials/studies) for this Bio-Agent, Comments

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Schuller, Hildegard M: 3 articles (02/2010 - 01/2007)
2.	Palma, Eleonora: 3 articles (01/2006 - 10/2002)
3.	Miledi, Ricardo: 3 articles (01/2006 - 10/2002)
4.	Eusebi, Fabrizio: 3 articles (01/2006 - 10/2002)
5.	Beck, H: 3 articles (01/2003 - 01/2000)
6.	Baulac, Stéphanie: 2 articles (11/2009 - 04/2004)
7.	Baulac, Michel: 2 articles (11/2009 - 04/2004)
8.	Zilles, Karl: 2 articles (01/2009 - 08/2005)
9.	Dean, Brian: 2 articles (08/2008 - 03/2004)
10.	Song, Bingbing: 2 articles (05/2008 - 07/2007)

Related Diseases

1.	Epilepsy (Aura) 10/01/1994 - "Recent PET studies of several neurotransmitter receptors in adult epileptic patients suggest that this approach holds great promise in the study of childhood epilepsy. " 11/12/2002 - "Expression of human epileptic temporal lobe neurotransmitter receptors in Xenopus oocytes: An innovative approach to study epilepsy." 04/01/1991 - "An exciting current application of PET scanning is the use of tracers for neurotransmitter receptors in the study of epilepsy patients. " 06/01/2006 - "Our findings suggest that neurotransmitter receptor gene expression is altered differently in immature and mature dentate granule neurons following SE, and may result in differential contributions of these two groups of dentate granule neurons to the subsequent development of epilepsy." 11/01/1993 - "PET and SPECT show physiologic derangements in epilepsy, including localized reductions in cerebral blood flow and metabolism and highly focal decreases in neurotransmitter receptor binding. " Order ALL the reference details at left...
2.	Ischemia 07/01/1998 - "We conclude that permanent local ischemia leads to a long-term and widespread impairment of the normal balance between binding sites of excitatory and inhibitory neurotransmitter receptors in neocortical areas far away from the focus of the post-ischemic tissue damage. " 01/01/1994 - "These results suggest that postischemic alterations of second-messenger (PKC) and neurotransmitter receptor systems were involved not only in the ischemic foci due to ischemia-induced energy failure, but also in the exo-focal remote areas prior to the histologic changes where neuronal damage might be caused by transsynaptic delayed degeneration." 09/01/1992 - "Preserved neurotransmitter receptor binding following ischemia in preconditioned gerbil brain." 01/01/1993 - "Neurotransmitter receptor-coupled mechanisms have been recently recognized as important determinants of cell damage after central nervous system (CNS) trauma and ischemia. " 12/03/2004 - "Protective effect of rhynchophylline and isorhynchophylline on in vitro ischemia-induced neuronal damage in the hippocampus: putative neurotransmitter receptors involved in their action." Order ALL the reference details at left...
3.	Autistic Disorder (Autism) 12/01/2001 - "Density and distribution of hippocampal neurotransmitter receptors in autism: an autoradiographic study." 01/01/1986 - "Relative affinities for different classes of neurotransmitter receptors predict neuroleptic efficacy in infantile autism: a hypothesis." 01/01/1986 - "In this report, the clinical efficacy of specific neuroleptics in infantile autism was related to the degree to which they bind to different classes of neurotransmitter receptors and calcium channels in brain. " 04/16/2004 - "A case of autism with an interstitial deletion on 4q leading to hemizygosity for genes encoding for glutamine and glycine neurotransmitter receptor sub-units (AMPA 2, GLRA3, GLRB) and neuropeptide receptors NPY1R, NPY5R." Order ALL the reference details at left...
4.	Vomiting 01/01/2006 - "This chapter briefly describes the physiological neural mechanisms by which diverse neurotransmitter receptor systems control several aspects of gastrointestinal functions such as motility, secretion, feeding, and emesis. " 01/01/1996 - "First the physiology of vomiting with the neurotransmitter receptor system and the neuroanatomical neuron pathway is reviewed. " 06/01/1985 - "In addition, antiemetic drug combinations that affect more than one neurotransmitter receptor have achieved improved emesis control. " 01/01/1993 - "The different emetic stimuli reach the vomiting centre by a variety of pathways and can be blocked by specific antiemetics that act at the neurotransmitter receptor sites in these pathways. " 03/01/1992 - "The availability of radiolabelled ligands selective for various putative neurotransmitter receptor sites and the development of quantitative autoradiography has led to a greater understanding of the neuronal pathway and receptor subtypes involved in the vomiting reflex induced by various mechanisms both within the central nervous system and the periphery. " Order ALL the reference details at left...
5.	Schizophrenia (Dementia Praecox) 06/01/2004 - "Numerous studies point to alterations in different aspects of brain development as possible causes of schizophrenia, including defects in neuronal migration, neurotransmitter receptor expression and myelination. " 01/01/1998 - "We propose that the study has identified a neurotransmitter receptor population which, in schizophrenia, undergoes misdirected reshaping during brain development. " 05/01/2008 - "Although these drugs act at several neurotransmitter receptors, they are expected to elicit different neuroadaptive changes at structures relevant for schizophrenia. " 02/01/2005 - "Recent findings regarding specific autoimmune responses directed against neurotransmitter receptors in the brain in patients with schizophrenia will also be reviewed." 07/01/2004 - "A role of many neurotransmitter receptors in schizophrenia was suggested by an association with several polymorphisms located in their coding regions. " Order ALL the reference details at left...

Related Drugs and Biologics

1.	Antipsychotic Agents (Antipsychotics)
2.	Alkaloids
3.	rhyncophylline
4.	Calcium Channels (Calcium Channel)
5.	Drug Combinations
6.	Neurotransmitter Agents (Neurotransmitter)
7.	GTP-Binding Proteins (G-Protein)
8.	Glutamic Acid (Glutamate)
9.	gamma-Aminobutyric Acid (GABA)
10.	Intercellular Signaling Peptides and Proteins (Growth Factors)

Related Therapies and Procedures

1.	Transplantation (Transplant Recipients)
2.	Therapeutics
3.	Drug Therapy (Chemotherapy)
4.	Investigational Therapies (Experimental Therapy)
5.	Spinal Injections

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