Photopheresis

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370 relevant articles (62 outcomes, 39 trials/studies) found for this Therapy

Description: A process in which peripheral blood is exposed in an extracorporeal flow system to photoactivated 8-methoxypsoralen (METHOXSALEN) and ultraviolet light - a procedure known as PUVA THERAPY. Photopheresis is at present a standard therapy for advanced cutaneous T-cell lymphoma; it shows promise in the treatment of autoimmune diseases.

Also Known As:

Extracorporeal Photochemotherapies; Photochemotherapies, Extracorporeal; Photopheresis, Extracorporeal; Extracorporeal Photochemotherapy; Extracorporeal Photopheresis; Photochemotherapy, Extracorporeal

Relationship Network

Therapy Context: Research Results

Therapeutics: 5229

Phototherapy: 2456

Ultraviolet Therapy: 73

PUVA Therapy: 490

Photopheresis: 370

Operative Surgical Procedures: 4

Extracorporeal Circulation: 1754

Photopheresis: 370

Experts

1.	Fimiani, M: 9 articles (03/2008 - 10/2000)
2.	Rubegni, P: 9 articles (03/2008 - 10/2000)
3.	De Aloe, G: 6 articles (03/2008 - 10/2000)
4.	Altmeyer, Peter: 6 articles (02/2007 - 01/2003)
5.	Sbano, P: 5 articles (03/2008 - 04/2004)
6.	Dassi, M: 5 articles (04/2006 - 03/2000)
7.	Perseghin, P: 5 articles (04/2006 - 03/2000)
8.	Kanold, J: 4 articles (03/2008 - 02/2000)
9.	Hoffmann, Klaus: 4 articles (01/2007 - 01/2003)
10.	Radenhausen, Michael: 4 articles (01/2007 - 01/2003)

Related Diseases

1.	Cutaneous T-Cell Lymphoma (Lymphoma, T Cell, Cutaneous) 10/01/2002 - "Since photopheresis, a treatment that induces an anticlonotypic immune response, has proven to be effective in both cutaneous T cell lymphomas with circulating clonal T cells and in cGVHD, we have searched for circulating clonal T cell populations in patients with cGVHD, and determined whether T cell clonality in the blood is associated with therapeutic response" 06/01/2004 - "Extracorporeal photochemotherapy (ECP), considered as an effective treatment for patients with erythrodermic cutaneous T-cell lymphoma (CTCL), has recently been used successfully in the treatment of GvHD" 10/01/1996 - "CONCLUSION: Photopheresis appears to be effective for selected patients with erythrodermic cutaneous T-cell lymphoma, although we did not achieve as high a remission rate as previously reported by others." 04/01/2005 - "The small-scale extracorporeal photopheresis therapy presented is effective in cutaneous T-cell lymphoma" 10/01/2002 - "BACKGROUND: Extracorporeal photopheresis (ECP) is an effective treatment for cutaneous T-cell lymphoma" Order ALL the reference details at left...
2.	Graft vs Host Disease (Graft-Versus-Host Disease) 07/01/2005 - "Recent studies suggest that extracorporeal photochemotherapy (ECP) may be beneficial in patients with steroid-refractory chronic graft-versus-host disease (cGvHD)" 10/01/2007 - "This study was aimed at ascertaining whether extracorporeal photopheresis (ECP) is an effective treatment for pediatric patients with steroid resistant graft versus host disease (GvHD)" 07/01/2003 - "This study aimed to ascertain whether extracorporeal photochemotherapy (ECP) is an effective treatment for paediatric patients with refractory graft-versus-host disease (GVHD)" 08/01/2008 - "Extracorporeal photopheresis (ECP) has been demonstrated to be clinically effective for the treatment of steroid-refractory graft-versus-host-disease (GvHD)" 03/15/2008 - "BACKGROUND: Extracorporeal Photopheresis (ECP) has been shown to be an effective treatment of graft-versus-host disease, solid organ graft rejection, and other T-cell-mediated diseases" Order ALL the reference details at left...
3.	Syndrome 05/01/2002 - "He is the only one of 55 patients with Sézary syndrome treated at Mayo Clinic (Rochester, Minnesota, USA) to achieve sustained remission on extracorporeal photopheresis alone." 10/01/2008 - "Various studies have reported that extracorporeal photopheresis is effective in producing meaningful responses in patients with Sézary syndrome" 10/01/2008 - "Extracorporeal photopheresis for the treatment of Sézary syndrome using a novel treatment protocol." 10/01/1991 - "Extracorporeal photochemotherapy is a well-tolerated treatment of palliative benefit for patients with the Sézary syndrome, but up to 25% of patients do not respond to this form of therapy" 12/01/1996 - "A possible exception is the effect of photopheresis in Sézary syndrome but our own experience differs from that in the USA and underlines the need to identify patients with clonal disease when defining subjects for study" Order ALL the reference details at left...
4.	Autoimmune Diseases (Autoimmune Disease) 12/01/1993 - "Photopheresis, comprising the treatment of lymphocytes by a combination of the light-activated drug methoxypsoralen and UVA irradiation, has been shown to be effective in the treatment of some other autoimmune disease" 06/01/1993 - "Extracorporeal photochemotherapy, an immune-modulating form of therapy, has been shown to be effective in the treatment of autoimmune diseases" 02/01/2000 - "Although several case reports and case series suggest efficacy for photopheresis in the treatment of autoimmune diseases, few controlled studies have been conducted to test this hypothesis" 02/01/2000 - "After a decade of interest, multiple case reports, open trials, and one controlled study, the role of photopheresis in autoimmune disease remains to be established" 04/01/1993 - "Additional conditions in which clinical studies have suggested a therapeutic role for photopheresis include certain autoimmune diseases and reversal of rejection of solid organ allografts" Order ALL the reference details at left...
5.	Systemic Scleroderma (Systemic Sclerosis) 03/01/1992 - "BACKGROUND AND DESIGN--In a pilot study of extracorporeal photochemotherapy, two patients with systemic sclerosis who received this therapy experienced significant clinical improvement" 05/01/2006 - "OBJECTIVE: Our aim was to evaluate the efficacy of photopheresis in the treatment of patients with systemic sclerosis (scleroderma)" 05/01/2006 - "A randomized, double-blind, placebo-controlled trial of photopheresis in systemic sclerosis." 01/01/1998 - "Thus far, the action of extracorporeal photopheresis (ECP) in severe systemic scleroderma has been evaluated in short-term studies, and only limited experience has been obtained with long-term application" 12/01/1994 - "Furthermore, a randomized, single-blinded trial involving 79 patients with early onset, aggressive systemic sclerosis suggested that photopheresis could benefically affect the course of the cutaneous thickening in this form of the disease" Order ALL the reference details at left...

Related Drugs and Biologics

1.	Interferon-alpha (Interferon Alfa)
2.	Methoxsalen (Oxsoralen)
3.	Psoralens
4.	Tacrolimus (Prograf)
5.	Dihydrotachysterol (AT 10)
6.	Ficusin (Psoralen)
7.	Collagen
8.	sargramostim (Leukine)
9.	Interferons
10.	Interleukin-10 (Interleukin 10)

Related Therapies and Procedures

1.	Photopheresis
2.	Transplants (Transplant)
3.	Homologous Transplantation (Allograft)
4.	Photochemotherapy (Photodynamic Therapy)
5.	Bone Marrow Transplantation (Transplantation, Bone Marrow)

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