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Exfoliation Syndrome

The deposition of flaky, translucent fibrillar material most conspicuous on the anterior lens capsule and pupillary margin but also in both surfaces of the iris, the zonules, trabecular meshwork, ciliary body, corneal endothelium, and orbital blood vessels. It sometimes forms a membrane on the anterior iris surface. Exfoliation refers to the shedding of pigment by the iris. (Newell, Ophthalmology, 7th ed, p380)
Also Known As:
Exfoliative Syndrome; Pseudo-Exfoliation Syndrome; Exfoliation Syndromes; Exfoliative Syndromes; Pseudo Exfoliation Syndrome; Pseudo-Exfoliation Syndromes; Pseudoexfoliation Syndromes; Syndrome, Exfoliation; Syndrome, Exfoliative; Syndrome, Pseudo-Exfoliation; Syndrome, Pseudoexfoliation; Syndromes, Exfoliation; Syndromes, Exfoliative; Syndromes, Pseudo-Exfoliation; Syndromes, Pseudoexfoliation; Glaucoma Capsulare; Pseudoexfoliation Syndrome
Networked: 311 relevant articles (11 outcomes, 40 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Glaucoma
2. Cataract (Cataracts)
3. Open-Angle Glaucoma (Glaucoma, Open Angle)
4. Dislocations
5. Angle-Closure Glaucoma (Glaucoma, Angle Closure)

Experts

1. Ritch, Robert: 11 articles (06/2015 - 07/2003)
2. Schlötzer-Schrehardt, Ursula: 11 articles (10/2014 - 12/2002)
3. Zenkel, Matthias: 9 articles (10/2014 - 06/2005)
4. Kruse, Friedrich E: 8 articles (09/2012 - 06/2005)
5. Schlötzer-Schrehardt, U: 8 articles (11/2005 - 06/2000)
6. Wiggs, Janey L: 6 articles (10/2015 - 01/2008)
7. Pasquale, Louis R: 6 articles (10/2015 - 09/2010)
8. Pasutto, Francesca: 6 articles (06/2015 - 12/2008)
9. Konstas, Anastasios G P: 6 articles (09/2013 - 12/2002)
10. Craig, Jamie E: 5 articles (06/2015 - 01/2008)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Exfoliation Syndrome:
1. Timolol (Blocadren)FDA LinkGeneric
2. bimatoprost (Lumigan)FDA Link
3. ArgonIBA
4. latanoprost (Xalatan)FDA Link
5. ibopamineIBA
6. Protein-Lysine 6-Oxidase (Lysyl Oxidase)IBA
7. Retinaldehyde (Retinal)IBA
8. HomocysteineIBA
9. ClusterinIBA
10. Matrix MetalloproteinasesIBA

Therapies and Procedures

1. Trabeculectomy (Trabeculoplasty)
2. Phacoemulsification
3. Lasers (Laser)
4. Intraocular Lenses (Intraocular Lens)
5. Cataract Extraction