|1.||Kenney, Shannon C: 2 articles (12/2015 - 07/2007)|
|2.||Wille, Coral K: 1 article (12/2015)|
|3.||Nawandar, Dhananjay M: 1 article (12/2015)|
|4.||Johannsen, Eric C: 1 article (12/2015)|
|5.||Henning, Amanda N: 1 article (12/2015)|
|6.||Ma, Shidong: 1 article (12/2015)|
|7.||Oetting, Kayla M: 1 article (12/2015)|
|8.||Lambert, Paul: 1 article (12/2015)|
|9.||Lee, Dennis: 1 article (12/2015)|
|10.||Everett, Roger D: 1 article (01/2015)|
01/01/2015 - "In the case of herpesviruses, intrinsic resistance involves the repression of viral gene expression during the very early stages of infection, a process that is normally overcome by viral tegument and/or immediate-early proteins. "
01/01/2014 - "Analysis of human cytomegalovirus-encoded SUMO targets and temporal regulation of SUMOylation of the immediate-early proteins IE1 and IE2 during infection."
10/01/2009 - "Of particular interest, even a brief suppression of rRNA synthesis resulted in a very strong inhibition of the progression of HCMV infection, as was concluded from the absence of accumulation of HCMV major immediate-early proteins within the nucleus of infected cells. "
07/01/2005 - "Additionally, we determined that in the context of virus infection ICP27 was sufficient for SAPK activation and activation of the p38 targets Mnk1 and MK2 by infecting with mutants deleted for various combinations of immediate-early proteins. "
12/15/2003 - "We also found that human CMV infection strongly trans-activates inhibitory ILT2 and ILT4 genes through the expression of immediate-early proteins."
09/01/1992 - "Heterologous viruses have been examined for their ability to accelerate the course of infection with the human immunodeficiency virus (HIV) type 1. In this study, ACH-2 cells persistently infected with HIV-1 exhibited augmented HIV-1 replication as a result of superinfection with herpes simplex virus (HSV) type 1. Using HSV-1 mutants with deletions in the genes encoding immediate-early proteins ICP0, ICP4, and ICP27, it was found that ICP0 and ICP27, but not ICP4, were essential for up-regulation of HIV replication. "
05/01/2011 - "We used quiescent infection of MRC-5 cells with a virus that does not express immediate-early proteins, followed by superinfection with various viral mutants to quantify the ability of ICP0 variants to reactivate gene expression and alter chromatin structure. "
|3.||Epstein-Barr Virus Infections
07/01/2007 - "The switch between latent and lytic EBV infection is mediated by the two viral immediate-early proteins BZLF1 (Z) and BRLF1 (R), which are not expressed in latently infected B cells. "
06/01/2001 - "Using the CD70-fiber bispecific antibody, we increased the ability of rAd vectors encoding the EBV immediate-early proteins BZLF1 and BRLF1 to induce the lytic form of EBV infection in LCLs. "
04/01/1999 - "However, expression of either of the EBV immediate-early proteins, BZLF1 and BRLF1, is sufficient to induce lytic EBV infection, resulting in death of the host cell. "
11/01/1985 - "It was also shown that the adenovirus and herpes pseudorabies immediate early proteins activate expression from the HTLV-I and HTLV-II long terminal repeats, though at lower levels than with the x gene product. "
07/15/1985 - "It has been previously reported that immediate early proteins of pseudorabies and cytomegalo viruses can substitute for the products of the human adenovirus type 5 (Ad5) E1A gene in the activation of early Ad5 transcription. "
|5.||Astrocytoma (Pilocytic Astrocytoma)
03/01/1995 - "In this paper, we have analysed the proliferative T cell response of healthy HCMV seropositive (HCMV+) blood donors to recombinant immediate-early proteins expressed in transfected astrocytoma cells and to total HCMV Ags expressed in infected astrocytoma cells. "
05/01/1995 - "Simultaneous detection of amplicon and HSV-1 helper encoded proteins reveals that neurons and astrocytoma cells do express amplicon-borne transgenes in the absence of synthesis of virus immediate early proteins."
|1.||Proteins (Proteins, Gene)
|5.||Viral Nonstructural Proteins
|6.||Trans-Activators (Trans-Acting Factor)
|7.||Transcription Factors (Transcription Factor)
|8.||Messenger RNA (mRNA)
|9.||RNA (Ribonucleic Acid)
|10.||Immunoglobulin G (IgG)