A member of the tumor necrosis factor receptor superfamily that may play a role in the regulation of NF-KAPPA B and APOPTOSIS. It is found on activated T-LYMPHOCYTES; B-LYMPHOCYTES; NEUTROPHILS; EOSINOPHILS; MAST CELLS and NK CELLS. Overexpression of the Ki-1 antigen in hematopoietic malignancies make it clinically useful as a biological tumor marker. Signaling of the receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS.
Also Known As:
Ber-H2 Antigen; CD30 Antigen; TNFRSF8 Receptor; Antigen, Ber-H2; Antigen, CD30; Antigen, Ki-1; Antigens, Ber-H2; Antigens, Ki 1; Ber H2 Antigen; Ber H2 Antigens; Ki 1 Antigen; Ki 1 Antigens; Receptor, TNFRSF8; Antigens, CD30; Antigens, Ki-1; Ber-H2 Antigens; CD30 Antigens; Ki-1 Antigens; Tumor Necrosis Factor Receptor Superfamily, Member 8