Anaplastic Large-Cell Lymphoma (Ki 1 Lymphoma)

Subscribe to Selected New Research on Anaplastic Large-Cell Lymphoma

606 relevant articles (14 outcomes, 35 trials/studies) found for this Disease

Description: A systemic, large-cell, non-Hodgkin, malignant lymphoma characterized by cells with pleomorphic appearance and expressing the CD30 ANTIGEN. These so-called "hallmark" cells have lobulated and indented nuclei. This lymphoma is often mistaken for metastatic carcinoma and MALIGNANT HISTIOCYTOSIS.

Also Known As:

Ki 1 Lymphoma; Lymphoma, Large-Cell, Anaplastic; CD30+ Anaplastic Large-Cell Lymphoma; Ki-1 Lymphoma; Systemic Anaplastic Large-Cell Lymphoma; Anaplastic Large Cell Lymphoma; Anaplastic Large-Cell Lymphomas; CD30 Positive Anaplastic Large Cell Lymphoma; CD30+ Anaplastic Large Cell Lymphoma; Ki-1 Lymphomas; Large-Cell Lymphoma, Anaplastic; Large-Cell Lymphomas, Anaplastic; Lymphoma, Anaplastic Large-Cell; Lymphoma, Ki-1; Lymphomas, Anaplastic Large-Cell; Lymphomas, Ki-1; Systemic Anaplastic Large Cell Lymphoma; CD30-Positive Anaplastic Large-Cell Lymphoma; Lymphoma, Large-Cell, Ki-1

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Lymphoma (Lymphomas)
2.	Non-Hodgkin Lymphoma (Lymphosarcoma)
3.	Mycosis Fungoides
4.	Hemophagocytic Lymphohistiocytosis (Hemophagocytic Syndrome)
5.	Neoplasms (Cancer)
86 Diseases and 322 more articles analyzed in the Full Patient-Physician Summary Report, order at left...

Experts

1.	Medeiros, L Jeffrey: 12 articles (09/2007 - 03/2003)
2.	Rassidakis, George Z: 12 articles (09/2007 - 03/2003)
3.	Lai, Raymond: 9 articles (10/2006 - 03/2003)
4.	Leventaki, Vasiliki: 5 articles (09/2007 - 08/2003)
5.	Amin, Hesham M: 5 articles (10/2006 - 08/2003)
6.	Merz, Hartmut: 4 articles (05/2004 - 04/2002)
7.	Lai, R: 3 articles (08/2008 - 03/2000)
8.	Amin, H M: 3 articles (08/2008 - 09/2001)
9.	Pulford, Karen: 3 articles (10/2007 - 02/2004)
10.	Lim, Megan S: 3 articles (09/2007 - 08/2007)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Anaplastic Large-Cell Lymphoma:

1.	Doxorubicin (Adriamycin)FDA LinkGeneric 06/01/2003 - "Secondary cutaneous anaplastic large cell lymphoma treated with liposomal doxorubicin (Doxil) leading to complete remission." 09/01/2002 - "From 1985 to 1998, 39 patients with Stage I or II World Health Organization classification anaplastic large cell lymphoma (ALCL; n = 20), peripheral T-cell lymphoma, unspecified (PTCLu; n = 11), or nasal-type NK/T-cell lymphoma (NKTCL; n = 8) were treated using doxorubicin-based chemotherapy (median, 6 cycles) with (n = 24) or without (n = 15) radiotherapy (median dose, 40 Gy)" 12/01/2006 - "The HSP90 inhibitor 17-AAG synergizes with doxorubicin and U0126 in anaplastic large cell lymphoma irrespective of ALK expression." 11/01/1993 - "RESULTS: The index patient and second patient were diagnosed as having Ki-1-positive anaplastic large-cell lymphoma by immunophenotyping and underwent cyclophosphamide, doxorubicin, prednisone, and vincristine (CHOP) chemotherapy with complete remission" Get all the results and reference details, order at left...
2.	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 12/01/2002 - "ALK is a tyrosine kinase oncogene initially found to be rearranged in anaplastic large-cell lymphomas (ALCL)" 09/01/2001 - "Inhibition of tyrosine kinase activity induces caspase-dependent apoptosis in anaplastic large cell lymphoma with NPM-ALK (p80) fusion protein." 08/15/2000 - "Immune response to the ALK oncogenic tyrosine kinase in patients with anaplastic large-cell lymphoma." 12/01/1999 - "The tyrosine kinase NPM-ALK, associated with anaplastic large cell lymphoma, binds the intracellular domain of the surface receptor CD30 but is not activated by CD30 stimulation." 12/01/1994 - "We have recently found a novel hyperphosphorylated 80-kD protein tyrosine kinase, p80, in a human Ki-1 lymphoma with this translocation" Get all the results and reference details, order at left...
3.	Phosphotransferases (Kinase)IBA 10/01/2008 - "Sixty-eight cases of anaplastic large cell lymphoma (44%) showed p63 nuclear positivity (41% of anaplastic large cell kinase positive and 47% of anaplastic large cell kinase negative)" 09/01/2007 - "NPM-ALK oncogenic kinase promotes cell-cycle progression through activation of JNK/cJun signaling in anaplastic large-cell lymphoma." 02/01/2007 - "Only a few scattered cells expressed CD30, but they showed no staining for anaplastic large-cell lymphoma kinase (ALK)" 10/01/2006 - "Some populations of IMT have anaplastic large cell lymphoma kinase (ALK) gene rearrangements"