Oral Lichen Planus

Oral lesions accompanying cutaneous lichen planus or often occurring alone. The buccal mucosa, lips, gingivae, floor of the mouth, and palate are usually affected (in a descending order of frequency). Typically, oral lesions consist of radiating white or gray, velvety, threadlike lines, arranged in a reticular pattern, at the intersection of which there may be minute, white, elevated dots or streaks (Wickham's striae). (Jablonski, Illustrated Dictionary of Dentistry)
Also Known As:
Lichen Planus, Oral
Networked: 712 relevant articles (69 outcomes, 183 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Squamous Cell Carcinoma (Epidermoid Carcinoma)
2. Oral Leukoplakia
3. Infection
4. Mouth Neoplasms (Oral Cancer)
5. Inflammation


1. Zeng, Xin: 12 articles (07/2014 - 06/2008)
2. Chen, Qianming: 11 articles (07/2014 - 02/2008)
3. Thongprasom, Kobkan: 8 articles (07/2015 - 03/2006)
4. Sun, Andy: 7 articles (02/2015 - 04/2002)
5. Dan, Hongxia: 7 articles (07/2014 - 06/2009)
6. Cheng, Bin: 7 articles (10/2013 - 03/2005)
7. Carrozzo, M: 7 articles (04/2011 - 01/2000)
8. Zhou, Gang: 6 articles (01/2015 - 03/2005)
9. Lin, Mei: 6 articles (11/2013 - 02/2008)
10. Porter, S R: 6 articles (04/2007 - 01/2000)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Oral Lichen Planus:
1. Tacrolimus (Prograf)FDA LinkGeneric
2. Adrenal Cortex Hormones (Corticosteroids)IBA
3. Triamcinolone Acetonide (Azmacort)FDA LinkGeneric
4. Clobetasol (Clobetasol Propionate)FDA LinkGeneric
5. pimecrolimus (Elidel)FDA Link
6. Cyclosporine (Ciclosporin)FDA LinkGeneric
7. Betamethasone (Celestone)FDA Link
8. 1-phenyl-3,3-dimethyltriazene (PDT)IBA
9. SteroidsIBA
10. Vitamin A (Retinol)FDA LinkGeneric

Therapies and Procedures

1. Photochemotherapy (Photodynamic Therapy)
2. Drug Therapy (Chemotherapy)
03/01/2010 - "The purpose of this study was to determine the efficacy of drug therapy of psychiatric disorders in oral lichen planus. "
03/01/2010 - "Because psychiatric disorders significantly influence the development and severity of oral lichen planus, the use of psychiatric drug therapy may be an adjunct in treatment. "
03/01/2010 - "The evaluation of psychiatric drug therapy on oral lichen planus patients with psychiatric disorders."
10/01/2010 - "Reliable evidence for management of oral submucous fibrosis is still limited; amifostine, hydrolytic enzymes, ice chips and Chinese medicine may be effective in preventing oral mucositis for patients with cancer receiving radiotherapy or chemotherapy; the evidence in treating oral mucositis with allopurinol mouthwash, granulocyte macrophage-colony stimulating factor, immunoglobulin or human placentral extract for patients with cancer receiving treatment is weak and unreliable yet; there is evidence that acyclovir is efficacious in prevention and treatment of herpes simplex virus infections in patients being treated for cancer; there is strong evidence that drugs absorbed or partially absorbed from the gastrointestinal tract prevent oral candidiasis in patients receiving treatment for cancer; relapses and adverse effects are common in using beta carotene, lycopene, vitamin A or retinoids to treat oral leukoplakia; only some weak evidence is provided in using cyclosporines, retinoids, steroids or phototherapy for treating oral lichen planus; the evidence about acyclovir for treating primary herpetic gingivostomatitis is insufficient; there is little research evidence for treatment of burning mouth syndrome. "
3. Low-Level Laser Therapy (LLLT)
4. Gas Lasers
5. Semiconductor Lasers