|1.||Wilms Tumor (Wilm's Tumor)
|3.||Mental Retardation (Idiocy)
|1.||Han, Joan C: 2 articles (11/2013 - 08/2008)|
|2.||Rennert, Owen M: 2 articles (11/2013 - 08/2008)|
|3.||Früh, B: 1 article (04/2015)|
|4.||August, P: 1 article (04/2015)|
|5.||Goldblum, D: 1 article (04/2015)|
|6.||Gerber-Hollbach, N: 1 article (04/2015)|
|7.||von Weissenfluh, C: 1 article (04/2015)|
|8.||Sharp, Stephen J: 1 article (11/2013)|
|9.||Tsao, Jack W: 1 article (11/2013)|
|10.||Butman, John A: 1 article (11/2013)|
|1.||Brain-Derived Neurotrophic Factor (BDNF)IBA
11/01/2013 - "In summary, among subjects with WAGR syndrome, BDNF+/- subjects had a mean Vineland Adaptive Behaviour Compose score that was 14-points lower and a mean intelligence quotient (IQ) that was 20-points lower than BDNF+/+ subjects. "
11/01/2013 - "We hypothesized that BDNF+/- would be associated with more severe cognitive impairment in subjects with WAGR syndrome. "
05/01/1999 - "Since this area is involved in a genetic disorder (WAGR syndrome) and because of interest in studying the regulation of the human BDNF gene, we have established a detailed transcript map of a 810-kb region clone in a yeast artificial chromosome (YAC), corresponding to a portion of this genomic locus. "
11/01/1994 - "A 1.7-Mb YAC contig around the human BDNF gene (11p13): integration of the physical, genetic, and cytogenetic maps in relation to WAGR syndrome."
03/10/2013 - "The variable appearance and/or description of haploinsufficiency for obesity susceptibility in the WAGR syndrome mainly depends on the critical region located within 80 kb of exon 1 of BDNF. "
|2.||DNA (Deoxyribonucleic Acid)IBA
08/01/1993 - "The WT1 gene was analysed using DNA from a Wilms' tumour derived from a patient with the WAGR syndrome using single strand conformation polymorphism analysis and polymerase chain reaction sequencing. "
10/03/1991 - "Wilms' tumour (WT), aniridia, genitourinary abnormalities and mental retardation form a symptom group (WAGR syndrome) associated with hemizygous deletions of DNA in chromosome band 11p13 (refs 1,2). "
|3.||Congenital diaphragmatic herniaIBA
12/01/2006 - "The first report of an association between WAGR syndrome and congenital diaphragmatic hernia has recently been published. "
05/01/2005 - "These cases demonstrate that congenital diaphragmatic hernia can be associated with WAGR syndrome and suggest that deletions of WT1 may predispose individuals to develop congenital diaphragmatic hernia."
05/01/2005 - "Congenital diaphragmatic hernia in WAGR syndrome."
|5.||Molecular Probes (Molecular Probe)IBA
|6.||Phosphoprotein Phosphatases (Phosphatases, Protein)IBA
|7.||gamma-Aminobutyric Acid (GABA)IBA
07/01/2006 - "We describe the clinical course, as well as cytogenetic and molecular findings, of a 3-year-old obese boy with psychomotor retardation who exhibited two rare conditions: succinic semialdehyde dehydrogenase deficiency (SSADH deficiency, MIM 271980), a disorder of gamma-aminobutyric acid metabolism with a heterogeneous clinical spectrum, and partial Wilms' tumor, aniridia, genital abnormalities, and mental retardation (WAGR) syndrome, an association between Wilms' tumor, aniridia, genitourinary malformations, and mental retardation due to mutations involving the short arm of chromosome 11, particularly deletions at the chromosomal region 11p13 (MIM 194072). "
|8.||Follicle Stimulating Hormone (Follitropin)FDA Link