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Radiation Pneumonitis (Radiation Fibrosis)

Inflammation of the lung due to harmful effects of ionizing or non-ionizing radiation.
Also Known As:
Radiation Fibrosis; Fibrosis, Radiation; Radiation Pneumonia; Pneumonias, Radiation; Pneumonitides, Radiation; Radiation Pneumonias; Radiation Pneumonitides; Pneumonia, Radiation; Pneumonitis, Radiation
Networked: 509 relevant articles (21 outcomes, 50 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Fibrosis (Cirrhosis)
2. Radiation Pneumonitis (Radiation Fibrosis)
3. Residual Neoplasm
4. Necrosis
5. Dyspnea (Shortness of Breath)

Experts

1. Liao, Zhongxing: 9 articles (05/2014 - 07/2007)
2. Guerrero, Thomas: 7 articles (01/2014 - 07/2007)
3. Bentzen, Søren M: 6 articles (05/2014 - 10/2010)
4. Wei, Qingyi: 6 articles (12/2013 - 07/2009)
5. Komaki, Ritsuko: 6 articles (09/2013 - 07/2007)
6. Senan, Suresh: 5 articles (09/2015 - 01/2004)
7. Wang, Li-E: 5 articles (04/2013 - 07/2009)
8. Farr, Katherina P: 4 articles (10/2015 - 05/2014)
9. Khalil, Azza A: 4 articles (10/2015 - 05/2014)
10. Castillo, Richard: 4 articles (06/2015 - 07/2012)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Radiation Pneumonitis:
1. Adrenal Cortex Hormones (Corticosteroids)IBA
2. erlotinib (CP 358,774)FDA Link
3. Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
4. Pentoxifylline (Trental)FDA LinkGeneric
5. Superoxide DismutaseIBA
6. Captopril (Capoten)FDA LinkGeneric
7. Octreotide (Sandostatin)FDA LinkGeneric
8. Vitamin EFDA LinkGeneric
9. CollagenIBA
10. gemcitabineFDA Link

Therapies and Procedures

1. Radiotherapy
12/01/2004 - "For the early detection of radiation pneumonitis following breast-conservation surgery, and to assess the efficacy of therapy, the monitoring and measuring of changes in KL-6 levels before and after radiotherapy is more important than comparing KL-6 levels against the threshold value. "
02/01/1985 - "On the low-dose regimen, one patient achieved partial response with IFN alone (duration, 12 weeks); of five evaluable patients three achieved complete remission and two partial remission to IFN-radiotherapy, and one of the three complete responders to IFN-radiotherapy died of severe radiation pneumonitis at 21 weeks from the start of IFN treatment. "
02/01/2006 - "Seventy percent of the patients (16/23) experienced improved perfusion at 40 - 50 Gy. > or = grade 2 radiation pneumonitis was observed in 12 patients (38.7%) in the whole group, with 6 in those with grade 1 perfusion defects and another 6 in > or = grade 2 group, respectively; Of the 23 patients who had had both pre- and post-radiotherapy SPECT perfusion scan, 5 > or = grade 2 radiation pneumonitis occurred in the 16 perfusion-improved patients and 3 in the 7 unimproved patients. "
01/01/2014 - "In the present study, we investigate whether there are relationships between the expressions of TLRs and the occurrence of radiation pneumonia in advanced NSCLC patients treated with radiotherapy. "
01/01/2013 - "Electronic databases, reference sections of major oncological textbooks and identified studies were searched for synonyms of breast radiotherapy and radiation pneumonitis (RP). "
2. Drug Therapy (Chemotherapy)
3. Brachytherapy
4. Aftercare (After-Treatment)
5. Adjuvant Chemotherapy