Mucinoses

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79 relevant articles (2 outcomes, 5 trials/studies) found for this Disease

Description: Mucoid states characterized by the elevated deposition and accumulation of mucin (mucopolysaccharides) in dermal tissue. The fibroblasts are responsible for the production of acid mucopolysaccharides (GLYCOSAMINOGLYCANS) in the ground substance of the connective tissue system. When fibroblasts produce abnormally large quantities of mucopolysaccharides as hyaluronic acid, chondroitin sulfate, or heparin, they accumulate in large amounts in the dermis.

Also Known As:

Mucinosis

Relationship Network

Disease Context: Research Results

Skin and Connective Tissue Diseases

Connective Tissue Diseases: 1629

Mucinoses: 79

Ganglion Cysts: 9485

Mucopolysaccharidoses: 881

Myxedema: 455

Scleromyxedema: 134

Follicular Mucinosis: 38

Scleredema Adultorum: 12

Related Diseases

1.	Syndrome
2.	Scleromyxedema (Lichen Myxedematosus)
3.	Wilms Tumor (Wilm's Tumor)
4.	Vascular Diseases (Vascular Disease)
5.	Neoplasms (Cancer)
45 Diseases and 38 more articles analyzed in the Research Interface, order at left...

Experts

1.	Fondevila, D: 1 article (10/2008)
2.	Zanna, G: 1 article (10/2008)
3.	Ferrer, L: 1 article (10/2008)
4.	Bardagí, M: 1 article (10/2008)
5.	Bassols, A: 1 article (10/2008)
6.	Docampo, M J: 1 article (10/2008)
7.	Fitzgerald, L: 1 article (03/2007)
8.	Thind, C: 1 article (03/2007)
9.	Burden, A D: 1 article (03/2007)
10.	Edward, M: 1 article (03/2007)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Mucinoses:

1.	pimecrolimus (Elidel)FDA Link 01/01/2007 - "We report on the efficacy of twice daily application of pimecrolimus 1 percent cream in a 48-year-old woman with reticular erythematous mucinosis (REM) syndrome and compare its results with pulsed dye laser (PDL) on the other side of her chest and back" 01/01/2007 - "Pimecrolimus 1 percent cream and pulsed dye laser in treatment of a patient with reticular erythematous mucinosis syndrome." Get all the results and reference details, order at left...
2.	MucinsIBA 10/01/2008 - "The aims of this study were to identify the composition of the mucin in cutaneous mucinosis of shar-pei dogs, investigate the correlation between the deposition of HA and the expression of CD44, and determine whether shar-pei dogs with cutaneous mucinosis presented with elevated levels of serum HA" 01/01/1969 - "Studies on the origin of the mucin in mucinosis follicularis." 03/01/2007 - "In primary cutaneous mucinosis, accumulation of mucin is a characteristic feature of lichen myxoedematosus, scleromyxoedema and reticular erythematous mucinosis" 10/01/2006 - "Cutaneous mucinoses, also called lichen myxoedematosus, are a group of diseases characterized by mucin deposit on the skin" 05/01/2005 - "The cutaneous mucinoses are a heterogeneous group of diseases in which mucin accumulates in the skin" Get all the results and reference details, order at left...
3.	Hyaluronic Acid (Hyaluronan)IBA 01/01/1981 - "Histochemical studies demonstrated that the material is different from the hyaluronic acid-rich substances of the usual forms of cutaneous mucinoses" 10/01/2008 - "Cutaneous mucinosis in shar-pei dogs is due to hyaluronic acid deposition and is associated with high levels of hyaluronic acid in serum." 11/01/1995 - "In these dogs, the only polysaccharidic compound involved in the dermal mucinosis was hyaluronic acid" 03/01/2007 - "Cutaneous mucinosis associated with dermatomyositis and nephrogenic fibrosing dermopathy: fibroblast hyaluronan synthesis and the effect of patient serum." 01/01/1986 - "This review discusses the primary mucinoses in which the predominant dermal mucin is hyaluronic acid" Get all the results and reference details, order at left...
4.	GlycosaminoglycansIBA 12/01/1962 - "Histochemical study of acid mucopolysaccharides in mucinoses." 02/01/1998 - "Cutaneous mucinoses are a heterogeneous group of diseases characterized by the focal or diffuse dermal deposition of glycosaminoglycans" 02/01/1997 - "Biochemical analysis revealed an increase in glycosaminoglycans in the involved skin as well as in the cutaneous lupus mucinosis" Get all the results and reference details, order at left...
5.	CollagenIBA 02/01/1998 - "We wanted to characterize the type I (COL1) and type III (COL3) collagen distribution in skin biopsy specimens of patients with cutaneous mucinosis" 02/01/1998 - "The histopathologic examination of many cutaneous mucinoses reveals that the collagen fibers are fragmented" 02/01/1998 - "Type I and type III collagens in cutaneous mucinosis." 02/01/1998 - "The mid-dermis showed intense staining for COL1 at the periphery of collagen bundles and, in three cases of familial papulonodular mucinosis and two cases of papular mucinosis, a lacy appearance" 03/01/1978 - "In addition to the case report, this article is concerned with a discussion of cutaneous mucinosis in LE and other "collagen vascular" diseases." Get all the results and reference details, order at left...
6.	Tryptophan (L-Tryptophan)FDA Link 07/01/1991 - "Tryptophan metabolites have been linked with sclerotic cutaneous diseases but have not been previously implicated in cutaneous mucinoses." 11/01/1990 - "Cutaneous mucinosis in a patient with eosinophilia-myalgia syndrome associated with L-tryptophan ingestion." Get all the results and reference details, order at left...
7.	SteroidsIBA 05/01/2003 - "Besides their strong anti-inflammatory effects, the long acting steroids and other preservative agents may induce interesting histopathological changes, which may simulate focal mucinosis or a granulomatous pathology" 01/01/1983 - "Intralesional steroids injected into hypertrophic scars and keloids can result in histiocytic and foreign body granulomatous reaction which may be confused with focal mucinosis or necrobiotic process such as rheumatoid nodule" Get all the results and reference details, order at left...
8.	Immunoglobulin M (IgM)IBA 09/01/1997 - "We report a case with the clinical and histological features of the reticular erythematous mucinosis syndrome (REM), in which there was moderate, continuous, fine, granular, IgM deposition along the basal layer" 01/01/1999 - "Biopsies in three patients showed features attributed to underlying connective tissue disease (CTD), including ectasia of the superficial vascular plexus, mild leukocytoclastic vasculitis, superficial and deep perivascular lymphocytic infiltrates with dermal mucinosis, granular deposition of IgM along the dermoepidermal junction indicative of a positive lupus band test, and of IgG and C5b-9 within keratinocytes" Get all the results and reference details, order at left...
9.	Immunoglobulin G (IgG)IBA 09/01/1993 - "Reticular erythematous mucinosis syndrome and a monoclonal IgG kappa paraprotein--is there an association?" 01/01/1999 - "Biopsies in three patients showed features attributed to underlying connective tissue disease (CTD), including ectasia of the superficial vascular plexus, mild leukocytoclastic vasculitis, superficial and deep perivascular lymphocytic infiltrates with dermal mucinosis, granular deposition of IgM along the dermoepidermal junction indicative of a positive lupus band test, and of IgG and C5b-9 within keratinocytes" Get all the results and reference details, order at left...
10.	Hydroxychloroquine (Plaquenil)FDA LinkGeneric 01/01/2003 - "The antimalarial hydroxychloroquine has a rapid and reliable effect in reticular erythematous mucinosis" 05/01/1993 - "Circulating immune complexes are increased in both reticular erythematous mucinosis and Jessner's lymphocytic infiltrate of skin and decrease with hydroxychloroquine therapy and clinical clearing" Get all the results and reference details, order at left...
39 Drugs and Important Bio-Agents and 72 more articles analyzed in the Research Interface, order at left...

Therapies and Procedures

1.	Dye Lasers 01/01/2007 - "We report on the efficacy of twice daily application of pimecrolimus 1 percent cream in a 48-year-old woman with reticular erythematous mucinosis (REM) syndrome and compare its results with pulsed dye laser (PDL) on the other side of her chest and back" 01/01/2007 - "Pimecrolimus 1 percent cream and pulsed dye laser in treatment of a patient with reticular erythematous mucinosis syndrome." Get all the results and reference details, order at left...
2.	Photopheresis 01/01/2001 - "Cutaneo-systemic papulosclerotic mucinosis (scleromyxedema): remission after extracorporeal photochemotherapy and corticoid bolus]" Get all the results and reference details, order at left...
3.	Drug Therapy (Chemotherapy) 01/01/1994 - "The patient in this study was an 8-year-old child who developed cutaneous lesions characteristic of self-healing juvenile cutaneous mucinosis while undergoing chemotherapy for a nephroblastoma" Get all the results and reference details, order at left...
4.	Transplantation (Transplant Recipients) 08/01/1998 - "We describe an immunosuppressed renal transplant recipient with the clinical diagnosis of cryptococcal cellulitis who was found to have a heretofore unreported dermal mucinosis of the upper chest associated with milia" 08/01/1998 - "Plaque-like erythema with milia: a noninfectious dermal mucinosis mimicking cryptococcal cellulitis in a renal transplant recipient." Get all the results and reference details, order at left...
5.	PUVA Therapy 01/01/2006 - "Both the erythroderma and generalized mucinosis responded to topical steroid and PUVA therapy" Get all the results and reference details, order at left...
8 Therapies and Procedures and 8 more articles analyzed in the Research Interface, order at left...

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