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Porokeratosis (Palmoplantar Porokeratosis)

A heritable disorder of faulty keratinization characterized by the proliferation of abnormal clones of KERATINOCYTES and lesions showing varying atrophic patches surrounded by an elevated, keratotic border. These keratotic lesions can progress to overt cutaneous neoplasm. Several clinical variants are recognized, including porokeratosis of Mibelli, linear porokeratosis, disseminated superficial actinic porokeratosis, palmoplantar porokeratosis, and punctate porokeratosis.
Also Known As:
Palmoplantar Porokeratosis; Porokeratosis of Mibelli; Linear Porokeratosis; Mibelli Porokeratosis; Punctate Porokeratosis; Porokeratosis Palmaris et Plantaris Disseminata; Porokeratosis, Disseminated Superficial Actinic; Porokeratosis, Linear; Porokeratosis, Mibelli; Porokeratosis, Palmoplantar; Porokeratosis, Punctate
Networked: 202 relevant articles (8 outcomes, 8 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Amyloidosis
2. Neoplasm Metastasis (Metastasis)
3. Hemangioma (Angioma)
4. Graft vs Host Disease (Graft-Versus-Host Disease)
5. Amyloid Plaque

Experts

1. Liu, Yan: 2 articles (01/2015 - 01/2012)
2. Yamamoto, Toshiyuki: 2 articles (12/2013 - 08/2012)
3. Kanitakis, J: 2 articles (08/2012 - 01/2001)
4. Berth-Jones, J: 2 articles (11/2008 - 02/2002)
5. Gilaberte, Yolanda: 1 article (11/2015)
6. Vera-Álvarez, Jesús: 1 article (11/2015)
7. García-Patos, Vicente: 1 article (11/2015)
8. Gracia-Cazaña, Tamara: 1 article (11/2015)
9. Parsi, Kurosh: 1 article (08/2015)
10. Frew, John W: 1 article (08/2015)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Porokeratosis:
1. imiquimod (Aldara)FDA LinkGeneric
2. Fluorouracil (Carac)FDA LinkGeneric
3. AcitretinFDA Link
4. PeplomycinIBA
5. Tacrolimus (Prograf)FDA LinkGeneric
6. EtretinateFDA Link
7. Amyloid (Amyloid Fibrils)IBA
8. Tretinoin (Retinoic Acid)FDA LinkGeneric
9. DNA (Deoxyribonucleic Acid)IBA
10. Burnett Schwartz Berberian syndromeIBA

Therapies and Procedures

1. Bone Marrow Transplantation (Transplantation, Bone Marrow)
2. Photochemotherapy (Photodynamic Therapy)
3. Dye Lasers
4. Lasers (Laser)
5. Subcutaneous Infusions