Seborrheic Keratosis

Benign eccrine poromas that present as multiple oval, brown-to-black plaques, located mostly on the chest and back. The age of onset is usually in the fourth or fifth decade.
Also Known As:
Keratosis, Seborrheic; Keratosis Seborrheica; Keratoses, Seborrheic; Seborrheic Keratoses
Networked: 210 relevant articles (10 outcomes, 16 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Nevus (Nevi)
2. Actinic Keratosis
3. Warts (Wart)
4. Keratosis
5. Nevus of Ota


1. Marghoob, Ashfaq A: 3 articles (07/2015 - 03/2007)
2. Jaimes, Natalia: 2 articles (07/2015 - 10/2013)
3. Dusza, Stephen W: 2 articles (07/2015 - 03/2007)
4. Murota, Hiroyuki: 2 articles (06/2015 - 02/2013)
5. Terao, Mika: 2 articles (06/2015 - 02/2013)
6. Katayama, Ichiro: 2 articles (06/2015 - 02/2013)
7. Tu, Yating: 2 articles (01/2014 - 07/2013)
8. Furue, Masutaka: 2 articles (07/2013 - 04/2013)
9. Brodell, Robert T: 2 articles (05/2013 - 05/2002)
10. Kanekura, Takuro: 2 articles (01/2011 - 11/2007)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Seborrheic Keratosis:
1. Lac-HydrinFDA LinkGeneric
2. DNA (Deoxyribonucleic Acid)IBA
4. Melanins (Melanin)IBA
05/01/2014 - "Indeed, the dermoscopy findings might be related to the melanin-rich necrotic cells in the epidermis, which are quite different from dermoscopy findings of clonal seborrheic keratosis. "
01/01/1987 - "No homogeneous inclusions typical of melanin macroglobules ("giant melanosomes") were found in any of the specimens, supporting the view that neither patterned nor nonpatterned seborrheic keratoses are nevoid in nature."
08/01/2004 - "In contrast, in pigmented seborrheic keratosis (SK), a similarly pigmented epidermal tumor, the distribution of melanin granules does not differ between the lesional ( approximately 93.9%) and the perilesional normal epidermis ( approximately 92.2 %), indicating that interrupted melanosome transfer occurs in BCE but not in all pigmented epithelial tumors. "
03/01/2007 - "Qualitative assessment suggested that melanin appeared darker and blue nevi had more shades of blue on PD compared with NPD images; vessels and red areas were better visualized with PD, suggesting that PD may be helpful in identifying malignancies; milialike cysts and comedolike openings were better visualized with NPD, suggesting that NPD is more helpful for identification of seborrheic keratosis; peppering, lighter colors, and blue-white areas were more evident under NPD, facilitating recognition of regression areas; and shiny-white streaks, possibly representing fibrosis, were seen more clearly under PD. "
07/01/2012 - "EEM measurements were performed on excised fresh normal skin tissues, seborrheic keratosis tissue samples, and skin fluorophores including: NADH, FAD, keratin, melanin, collagen, and elastin. "
5. NitrogenIBA
6. Lidocaine (Xylocaine)FDA LinkGeneric
7. adalimumab (Humira)FDA Link
8. neodymium pyrocatechin disulfonate (NPD)IBA
9. EMLAFDA LinkGeneric
10. styrene-methylmethacrylate copolymerIBA

Therapies and Procedures

1. Solid-State Lasers
2. Cryosurgery
3. Gas Lasers
4. Dye Lasers
5. Transplantation (Transplant Recipients)