Specific receptors on cell membranes that react with PLATELET-DERIVED GROWTH FACTOR, its analogs, or antagonists. The alpha PDGF receptor (RECEPTOR, PLATELET-DERIVED GROWTH FACTOR ALPHA) and the beta PDGF receptor (RECEPTOR, PLATELET-DERIVED GROWTH FACTOR BETA) are the two principle types of PDGF receptors. Activation of the protein-tyrosine kinase activity of the receptors occurs by ligand-induced dimerization or heterodimerization of PDGF receptor types.
Also Known As:
Platelet-Derived Growth Factor Receptor; Receptors, Platelet Derived Growth Factor; Receptors, Platelet-Derived Growth Factor; PDGF Receptor; Platelet Derived Growth Factor Receptor; Platelet Derived Growth Factor Receptors; Receptor, PDGF; PDGF Receptors; Receptors, PDGF