|1.||Zeng, Zhao-Zhu: 2 articles (10/2011 - 12/2004)|
|2.||Livant, Donna L: 2 articles (10/2011 - 12/2004)|
|3.||van Hoorn, Hedde: 1 article (04/2015)|
|4.||Schmidt, Thomas: 1 article (04/2015)|
|5.||Danen, Erik H J: 1 article (04/2015)|
|6.||Balcioglu, Hayri E: 1 article (04/2015)|
|7.||Donato, Dominique M: 1 article (04/2015)|
|8.||Ben-Josef, Edgar: 1 article (10/2011)|
|9.||Staszewski, Evan D: 1 article (10/2011)|
|10.||Spalding, Aaron C: 1 article (10/2011)|
08/15/2003 - "The alpha(5)beta(1) integrin is one of the major fibronectin receptors which plays an essential role in the adhesion of normal and tumor cells to extracellular matrix. "
09/01/1995 - "In particular, the fibronectin receptors, alpha 4 and alpha 5, were absent in the epithelial regions of the cervical cancers, and alpha 3 also had diminished expression in the malignant epithelium. "
02/27/1981 - "After metastasis, fibronectin receptors are apparently restored in those secondary tumor foci that become established. "
04/01/2015 - "During development, angiogenesis, wound healing and cancer progression, the relative abundance of fibronectin receptors, including integrins α5β1 and αvβ3, changes, thus altering the integrin composition of cell-matrix adhesions. "
11/01/1992 - "Similarly, altered expression pattern of many other adhesion molecules such as upregulated expression of the laminin receptors and depressed expression of fibronectin receptors (alpha 5 beta 1) appears to be involved in tumor cell invasion into the subendothelial matrix. "
03/01/1993 - "Comparison of the model with data at 37 degrees C suggests that while cytoskeletal cross-linking and clustering of fibronectin receptors significantly increases adhesion strength, specific glioma cell-substratum attachment sites possess little mechanical rigidity and detach through a peeling mechanism, consistent with the view that these sites of < or = 15 nm cell-substrate separation are precursors to fully formed, elastically rigid focal contacts."
10/03/1994 - "Localization of vitronectin- and fibronectin-receptors on cultured human glioma cells."
03/01/1993 - "Our model successfully predicts the observed detachment forces at 4 degrees C and yields values for the number of fibronectin receptors per glioma cell and the density of cytoskeletal connection molecules (talin) involved in receptor clusters which are consistent with measurements for other cell types. "
11/01/1998 - "Four glioma cells derived from GB whose tumor cells did not positively stain for fibronectin receptors migrated much less extensively to fibronectin than other glioma cells whose tissues showed positive staining for the fibronectin receptor. "
06/19/1992 - "All cell lines tested expressed alpha V beta 1. Human neuroblastoma cells, the majority of which are N-type cells with very low alpha 5 beta 1 expression, are also contrasted with other childhood cancer cells (rhabdomyosarcoma, Ewing's sarcoma, and glioma), all of which expressed high levels of alpha 5 beta 1. The characteristic expression of integrin fibronectin receptors may account for the clinically unique tumor behavior, and the immunohistochemical staining for integrins may become a useful alternative to conventional histology in differential diagnosis and a marker for prognosis in neuroblastoma."
|3.||Wounds and Injuries (Trauma)
06/01/1990 - "Fibronectin receptors were expressed by fibroblasts just prior to wound contraction."
01/01/1990 - "Neither actin bundles nor fibronectin receptors were observed in 5-d wound fibroblasts. "
06/01/1990 - "Day-7 wound fibroblasts expressed fibronectin receptors, contained peripheral cytoplasmic actin bundles consistent with a contractile fibroblast phenotype, and were coaligned across the wound in parallel array with interconnecting fibronectin fibrils. "
01/01/1990 - "These cells expressed fibronectin receptors, were embedded in a fibronectin matrix that appeared to connect fibroblasts to the matrix and to each other, and were coaligned across the wound. "
07/01/1996 - "Although alpha 5 beta 1 integrin, a fibronectin receptor, is expressed by human epidermis during re-epithelialization of excisional and incisional wounds, the spatial and temporal patterns of vitronectin, tenascin, and other fibronectin receptors are less clear. "
|4.||Melanoma (Melanoma, Malignant)
06/17/2009 - "M2 melanoma cells null for filamin A do not alter their adherent area in response to increased substrate stiffness when they link to the substrate only through collagen receptors, but change adherent area normally when bound through fibronectin receptors. "
01/01/2008 - "The expression of alpha(3)beta(1), alpha(4)beta(1), alpha(5)beta(1), and alpha(v)beta(3) integrins, acting as fibronectin receptors, differed between the tested cell lines, and no distinct pattern distinguished uveal melanoma from cutaneous melanoma except for high expression of alpha(4)beta(1) integrin on both FM55P and IGR-39 cells. "
|5.||Integrin alpha4beta1 (VLA-4)