HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Somatomedin Receptors (Somatomedin Receptor)

Cell surface receptors that bind somatomedins and trigger intracellular changes which influence the behavior of cells. Studies have disclosed two types of receptors for this family of peptide hormones. The type I receptor is homologous to the insulin receptor and has tyrosine kinase activity. The type II receptor is identical to the mannose-6-phosphate receptor which is important in trafficking of lysosomal enzymes.
Also Known As:
Somatomedin Receptor; Insulin-Like Growth Factor Receptor; Receptors, Somatomedin; Insulin-Like Growth Factor Receptors; Insulin Like Growth Factor Receptor; Insulin Like Growth Factor Receptors; Receptor, Somatomedin; Receptors, Insulin Like Growth Factors; Receptors, Insulin-Like Growth Factors
Networked: 522 relevant articles (14 outcomes, 57 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Yee, Douglas: 14 articles (10/2021 - 12/2003)
2. Moorehead, Roger A: 12 articles (01/2021 - 05/2008)
3. Macaulay, Valentine M: 12 articles (01/2020 - 05/2002)
4. Amin, Hesham M: 8 articles (01/2019 - 07/2009)
5. Lee, Adrian V: 8 articles (01/2018 - 02/2004)
6. Sachdev, Deepali: 8 articles (01/2015 - 02/2004)
7. Belfiore, Antonino: 7 articles (01/2021 - 09/2007)
8. Shi, Ping: 7 articles (01/2019 - 07/2009)
9. Macaulay, V M: 7 articles (11/2014 - 07/2001)
10. Lee, Ho-Young: 6 articles (01/2021 - 07/2011)

Related Diseases

1. Neoplasms (Cancer)
2. Breast Neoplasms (Breast Cancer)
3. Colorectal Neoplasms (Colorectal Cancer)
4. Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
5. Sarcoma (Soft Tissue Sarcoma)

Related Drugs and Biologics

1. Insulin Receptor
2. Messenger RNA (mRNA)
3. Protein-Tyrosine Kinases (Tyrosine Kinase)
4. RNA (Ribonucleic Acid)
5. Proteins (Proteins, Gene)
6. Phosphotransferases (Kinase)
7. Insulin-Like Peptides
8. Tyrosine Kinase Inhibitors
9. 3- (8- amino- 1- (2- phenylquinolin- 7- yl)imidazo(1,5- a)pyrazin- 3- yl)- 1- methylcyclobutanol
10. MicroRNAs (MicroRNA)

Related Therapies and Procedures

1. Radiotherapy
2. Therapeutics
3. Molecular Targeted Therapy
4. Drug Therapy (Chemotherapy)
5. Immunotherapy