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U2 Small Nuclear Ribonucleoprotein

A nuclear RNA-protein complex that plays a role in RNA processing. In the nucleoplasm, the U2 snRNP along with other small nuclear ribonucleoproteins (U1, U4-U6, and U5) assemble into SPLICEOSOMES that remove introns from pre-mRNA by splicing. The U2 snRNA forms base pairs with conserved sequence motifs at the branch point, which associates with a heat- and RNAase-sensitive factor in an early step of splicing.
Also Known As:
Ribonucleoprotein, U2 Small Nuclear; Ribonucleoproteins, Small, U2; Small Nuclear Ribonucleoproteins, U2; U2 Small Nuclear Ribonucleoproteins; U2 snRNP
Networked: 14 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Holditch, Sara J: 1 article (08/2015)
2. Hickey, Raymond D: 1 article (08/2015)
3. Basu, Upamanyu: 1 article (08/2015)
4. Bressin, Robert K: 1 article (08/2015)
5. Ikeda, Yasuhiro: 1 article (08/2015)
6. Koide, Kazunori: 1 article (08/2015)
7. Sakuma, Toshie: 1 article (08/2015)
8. Schreiber, Claire A: 1 article (08/2015)
9. Asokan, Aravind: 1 article (08/2015)
10. Izumiya, Yoshihiro: 1 article (08/2015)

Related Diseases

1. Neoplasms (Cancer)
2. Infection
3. Vesicular Stomatitis
4. Progressive Myoclonic Epilepsies (Progressive Myoclonic Epilepsy)
5. Polymyositis

Related Drugs and Biologics

1. Small Nuclear Ribonucleoproteins (snRNP)
2. Autoantibodies
3. U1 Small Nuclear Ribonucleoprotein
4. Proteins (Proteins, Gene)
5. Eukaryotic Initiation Factor-4E
6. Small Interfering RNA (siRNA)
7. RNA Splice Sites
8. U4-U6 Small Nuclear Ribonucleoprotein
9. Staphylococcal Protein A (A, Protein)
10. RNA Precursors (Precursor, mRNA)