Paroxetine (Paxil)
981
relevant articles (162 outcomes,
235 trials/studies)
found for this Drug
Description:
A serotonin uptake inhibitor that is effective in the treatment of depression.
Also Known As:
Paxil; Seroxat; Aropax; Paroxetine Hydrochloride; BRL-29060; FG-7051; Paroxetine Acetate; Paroxetine Hydrochloride, Hemihydrate; Paroxetine Maleate; Paroxetine, cis-(+)-Isomer; Paroxetine, cis-(-)-Isomer; Paroxetine, trans-(+)-Isomer; Acetate, Paroxetine; BRL 29060; BRL29060; Hemihydrate Paroxetine Hydrochloride; Hydrochloride, Hemihydrate Paroxetine; Hydrochloride, Paroxetine; Maleate, Paroxetine; Piperidine, 3-((1,3-benzodioxol-5-yloxy)methyl)-4-(4-fluorophenyl)-, (3S-trans)-
Relationship Network
Drug Context: Research Results
Experts
| 1. | Stein, Dan J:
6 articles
(04/2007 - 02/2002)
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| 2. | Wagner, Karen Dineen:
6 articles
(06/2006 - 01/2003)
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| 3. | Carpenter, David J:
6 articles
(06/2006 - 11/2004)
|
| 4. | Simon, Naomi M:
5 articles
(05/2008 - 09/2003)
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| 5. | Pollack, Mark H:
5 articles
(05/2008 - 01/2003)
|
| 6. | Stein, Murray B:
5 articles
(03/2008 - 01/2002)
|
| 7. | Zaninelli, R:
5 articles
(12/2001 - 01/2000)
|
| 8. | Krulewicz, Stan:
4 articles
(03/2008 - 04/2006)
|
| 9. | Beebe, Katherine L:
4 articles
(05/2007 - 06/2003)
|
| 10. | Denys, Damiaan:
4 articles
(05/2007 - 12/2003)
|
Related Diseases
| 1. | Anxiety Disorders (Anxiety Disorder)
05/01/2005
- " Paroxetine has been the most studied agent in social anxiety disorder and has been shown to be effective in short-term, fixed- and flexible-dose placebo-controlled trials, as well as in long-term treatment" 01/01/2002
- " CONCLUSION: Paroxetine, 20 mg/day, is an effective and safe treatment for patients with generalized social anxiety disorder and significantly improves social anxiety, avoidance of social interactions, social disability, and overall clinical condition" 12/01/2004
- " RESULTS: In general, across the range of anxiety disorders studied, in both short- and long-term studies, remission rates were higher for paroxetine compared with placebo, using disorder-specific, global, and functional remission criteria both individually and combined" 02/01/2007
- " While the overall efficacy of paroxetine appears to be comparable with other SSRIs in the treatment of major depression, it is approved for use in a wider variety of anxiety disorders than any other antidepressant" 01/01/2003
- " An abundance of data have been accumulated from clinical investigations demonstrating the efficacy of paroxetine in the treatment of major depression and anxiety disorders"
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| 2. | Panic Disorder (Panic Attack)
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| 3. | Post-Traumatic Stress Disorders (PTSD)
02/01/1998
- " Because paroxetine seems a highly promising treatment for all three symptom clusters of PTSD, a placebo-controlled clinical trial is warranted." 10/01/2003
- " Paroxetine is effective in the short-term treatment of PTSD, resulting in significantly better response and remission rates than placebo, improving sleep disturbance and reducing each of the symptom clusters of PTSD, as well as the disability associated with this condition" 12/01/2001
- " Moreover, paroxetine treatment resulted in statistically significant improvement compared to placebo on all three PTSD symptom clusters (reexperiencing, avoidance/numbing, and hyperarousal), social and occupational impairment, and comorbid depression" 11/01/2001
- " At week 12, compared with the placebo group (N = 156), the paroxetine group (N = 151) showed significantly greater reduction of PTSD symptoms on both of the primary and all of the secondary outcome measures" 02/01/1998
- " The authors hypothesized that paroxetine might be effective in PTSD, based on findings of its particular efficacy for anxiety and agitation in studies of depressed patients"
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| 4. | Phobic Disorders (Phobia)
09/01/1998
- " Paroxetine, the most thoroughly studied SSRI, has been shown to be effective in treating the symptoms of generalized social phobia in a large-scale, placebo-controlled trial" 08/01/2003
- " Treatment with paroxetine was associated with a significant improvement in standard social-phobia scores, although most patients remained symptomatic" 10/01/2001
- " Subjects were 14 patients with generalized social phobia who were less than "very much improved" on the Clinical Global Impression scale after at least 10 weeks of treatment with a maximally tolerated dose of paroxetine" 12/01/2002
- " Compared with placebo, paroxetine treatment significantly (P<.001) improved the symptoms of social anxiety as shown on the Liebowitz Social Anxiety Scale, Social Phobia Inventory, Sheehan Disability Scale, Symptom Checklist-90 score, and EuroQol visual analogue scale, indicating decreased disability and increased well-being" 08/01/1999
- " CONCLUSIONS: Paroxetine is an effective, well-tolerated treatment for patients with social phobia."
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| 5. | Obsessive-Compulsive Disorder (Disorder, Obsessive-Compulsive)
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| 261 Diseases
and
981
more articles analyzed in the Research Interface, order at left...
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