|1.||Kline, Anthony E: 7 articles (05/2012 - 11/2002)|
|2.||Scrogin, Karie E: 5 articles (09/2012 - 03/2003)|
|3.||Zafonte, Ross D: 5 articles (12/2008 - 11/2002)|
|4.||Tiniakov, Ruslan: 4 articles (09/2012 - 11/2006)|
|5.||Uphouse, Lynda: 4 articles (04/2007 - 06/2002)|
|6.||Cheng, Jeffrey P: 3 articles (05/2012 - 04/2007)|
|7.||Nalivaiko, Eugene: 3 articles (02/2009 - 08/2005)|
|8.||Sugimoto, Y: 3 articles (10/2001 - 08/2000)|
|9.||Song, Zhenquan: 2 articles (04/2015 - 01/2013)|
|10.||Li, Bin: 2 articles (04/2015 - 01/2013)|
07/01/1993 - "The hypothermia, but not the behavioural syndrome induced by 8-OH-DPAT was significantly greater in female compared with male rats. "
02/16/2009 - "8-OH-DPAT caused prolongation of basal RR interval, increase in locomotion and hypothermia. "
03/08/2004 - "8-OH-DPAT acts on both 5-HT1A and 5-HT7 receptors to induce hypothermia in rodents."
02/01/2004 - "These data confirm that a single systemic administration of 8-OH-DPAT confers neurological protection after TBI, and demonstrate that the beneficial effect is not mediated by concomitant hypothermia. "
02/01/2004 - "However, 8-OH-DPAT also produced mild hypothermia (Hypo), which may have contributed to the benefit. "
09/03/1993 - "Intra-HIP injection of 8-OH-DPAT (10 nmol) produced a significant elevation in the afterdischarge threshold of partial HIP seizures, with a significant reduction in the duration of focal afterdischarge. "
09/01/2005 - "Concerning KA, 8-OH-DPAT augmented the latency and reduced the frequency of wet-dog shake (WDS) and generalized seizure (GS). "
09/01/2005 - "8-OH-DPAT decreased the incidence of tonic seizures and the mortality rate induced by PTZ. "
02/01/1991 - "In the present study, we examined the clonic seizure immediately preceding head-weaving behaviour elicited by 8-OH-DPAT (40 mg/kg, ip) administration in mice. "
06/01/2007 - "Rats pretreated with 8-OH-DPAT presented augmented latency for wet dog shakes (71%), generalized seizures (54%) and behavioral SE (31%). "
|3.||Brain Injuries (Brain Injury)
01/15/2013 - "Previous studies have reported a neuroprotective effect of 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT) against traumatic brain injury. "
04/01/2015 - "The role of 8-OH-DPAT on the rat neuronal apoptosis after diffuse brain injury coupled with secondary brain injury."
05/02/2012 - "8-OH-DPAT is a 5-HT(1A/7) receptor agonist that enhances behavioral recovery after traumatic brain injury (TBI). "
11/01/2010 - "Evaluation of a combined therapeutic regimen of 8-OH-DPAT and environmental enrichment after experimental traumatic brain injury."
04/12/2007 - "The neurobehavioral benefit conferred by a single systemic administration of 8-OH-DPAT after brain trauma is confined to a narrow therapeutic window."
04/16/2007 - "These findings allow the suggestion that DOI's ability to increase PKC may be responsible for attenuation of the effects of 8-OH-DPAT on lordosis behavior."
04/16/2007 - "8-OH-DPAT inhibited lordosis behavior and DOI reduced this inhibition. "
04/16/2007 - "The PKC inhibitor, bisindolymaleimide, blocks DOI's attenuation of the effects of 8-OH-DPAT on female rat lordosis behavior."
08/01/2005 - "These results suggest that 8-OH-DPAT acts on areas other than the DRN and the septum, leading to a decrease in lordosis. "
07/09/2004 - "8-OH-DPAT inhibited lordosis behavior within 15 min of the infusion and every dose of WAY100635 prevented the inhibition. "
|5.||AIDS-Related Complex (ARC)
07/01/2014 - "Social defeat increased the number of Arc immunopositive cells in the central amygdala (CeA), prelimbic cortex (PL), and BLA, and 8-OH-DPAT treatment reduced Arc immunoreactivity in the PL. "
07/01/2014 - "In a separate experiment, we administered 8-OH-DPAT prior to 3, 5-minute social defeats and later removed the brains for Arc immunohistochemistry. "
01/01/2012 - "Photic induction of the immediate early genes c-FOS, EGR-1 and ARC was not altered, and neither was phase-shifting in response to treatment with the 5-HT-1a/7 agonist 8-OH-DPAT. "
04/19/2010 - "The previous treatment with WAY100635 in the ARC also suppressed the feeding duration decrease evoked by 8-OH-DPAT in estrus. "
04/19/2010 - "The ARC pretreatment with WAY100635 blockaded the hypophagia evoked by 8-OH-DPAT in estrus rats. "
|1.||5-HT1A Serotonin Receptor
|2.||Serotonin (5 Hydroxytryptamine)
|6.||Serotonin 5-HT1 Receptor Agonists