|5.||Hypertension (High Blood Pressure)
|1.||Martin, James N: 13 articles (10/2013 - 01/2003)|
|2.||Rigó, János: 9 articles (04/2012 - 09/2007)|
|3.||Owens, Michelle Y: 8 articles (01/2016 - 03/2011)|
|4.||Molvarec, Attila: 8 articles (04/2012 - 03/2008)|
|5.||Vigil-De Gracia, Paulino: 7 articles (06/2015 - 09/2006)|
|6.||May, Warren L: 7 articles (01/2012 - 01/2003)|
|7.||Hupuczi, Petronella: 7 articles (01/2009 - 03/2006)|
|8.||Zusterzeel, P L: 7 articles (12/2001 - 01/2000)|
|9.||Peters, W H: 7 articles (12/2001 - 01/2000)|
|10.||Steegers, E A: 7 articles (12/2001 - 01/2000)|
12/01/2012 - "Maternal corticosteroid administration has been reported to improve the blood pressure, urine output, laboratory values of liver enzymes and platelets in HELLP syndrome. "
10/01/2009 - "A total of 20 women with HELLP syndrome (haemolysis, elevated liver enzymes and low platelets), and 20 gestational age-matched healthy controls participated in this study which was conducted at Assiut University Maternity Hospital, Egypt. "
06/01/2014 - "We present here an unusual case of Haemolysis, Elevated Liver enzymes and Low Platelets (HELLP) syndrome, which represents this diagnostic dilemma. "
01/01/2014 - "The HELLP syndrome (haemolysis, elevated liver enzymes, and low-platelet count) occurs in about 0.5 to 0.9% of all pregnancies. "
12/01/2013 - "In evaluation of the case, laboratory findings which were associated with HELLP syndrome were found to include haemolysis, elevated liver enzymes and low platelet counts. "
|2.||Dexamethasone (Maxidex)FDA LinkGeneric
04/01/1999 - "We report a patient with HELLP syndrome in whom antenatal administration of high-dose dexamethasone helped achieve disease stabilization and delivery postponement for 9 days of a very preterm fetus estimated to weight less than 600 g. "
02/01/2008 - "the present study is a secondary analysis of a randomized clinical trial design to evaluate the efficacy of dexamethasone in patients with HELLP syndrome. "
02/01/2008 - "to describe the clinical and laboratorial profile of HELLP syndrome patients admitted at an Obstetric Intensive Care Unit (ICU) and included in a randomized clinical trial to evaluate the efficacy of dexamethasone in this clinical setting. "
12/01/2006 - "Dexamethasone, HELLP syndrome, and study design."
05/01/2013 - "We conclude that 1 important mechanism of dexamethasone administration is to blunt the release of both antiangiogenic and inflammatory factors suggested to play role in the pathophysiology of HELLP syndrome."
|3.||Adrenal Cortex Hormones (Corticosteroids)IBA
08/01/1999 - "This study demonstrates that corticosteroids produce a significant improvement in the hematologic abnormalities associated with HELLP syndrome. "
08/01/1999 - "The hematologic abnormalities seen in the 93 patients with HELLP syndrome improved after the administration of corticosteroids. "
05/01/2013 - "Seeking the mechanism(s) of action for corticosteroids in HELLP syndrome: SMASH study."
01/01/2009 - "Randomised and quasi-randomised trials evaluating the effects of adjunctive corticosteroids in patients diagnosed with HELLP syndrome were sought. "
09/07/2006 - "Treatment can give a faster increase in the platelet count for patients with platelets < 50 (10(9)/L), but larger trials are needed to support the use of corticosteroids for treatment of HELLP-syndrome."
06/01/1993 - "Administration of haptoglobin and blood purification would be beneficial for patients complicated with HELLP syndrome."
11/01/2000 - "Efficacy of haptoglobin administration in the early postoperative course of patients with a diagnosis of HELLP syndrome."
03/01/2003 - "Haptoglobin and its association with the HELLP syndrome."
09/01/2001 - "- The disease course was reevaluated in 37 patients who developed HELLP syndrome (thrombocytes < 100 000/microl, transaminase > 70 U/l, haptoglobin < 0.5 g/l) between 1994 and 1999. "
01/01/1999 - "The percentage of preeclamptic patients (26.9%) or patients with the HELLP syndrome (73.5%) with elevated GSTP1-1 levels was lower than those with elevated LDH (38.8% and 100%, respectively) or decreased haptoglobin levels (41.8% and 97%, respectively). "
04/01/1999 - "The monitoring of AT-III activity and platelet count in women who exhibit a gradual decline in these parameters may help to avoid the development of severe HELLP syndrome."
08/01/1998 - "Monitoring of AT-III activity might help to avoid the development of severe HELLP syndrome."
08/01/1998 - "Triplet pregnancy complicated by a gradual decline in antithrombin-III activity and HELLP syndrome: a case report."
05/01/2002 - "Results shows a difference (P<0,05 ) for AT III and other markers levels in the two groups and, inside of the SPH group, between Severe preeclampsia patients and HELLP syndrome patients. "
08/01/1998 - "A gradual decline in AT-III activity occurred in the absence of clinical signs of preeclampsia and preceded the onset of the typical HELLP syndrome in this patient. "
|6.||Prednisolone (Predate)FDA LinkGeneric
09/01/2006 - "A randomised placebo-controlled trial of prolonged prednisolone administration to patients with HELLP syndrome remote from term."
01/01/2008 - "Blood samples from patients with HELLP syndrome who were receiving either prednisolone or placebo were obtained before, during, and after a HELLP exacerbation in the antepartum period. "
01/01/2008 - "To investigate the effect of prednisolone on HELLP syndrome by assessing several markers of the inflammatory response and hepatic damage associated with HELLP syndrome. "
01/01/2008 - "HELLP syndrome is associated with an increased inflammatory response, which may be inhibited by administration of prednisolone."
09/01/2006 - "When expectant management is pursued in selected patients with a HELLP syndrome remote from term, prolonged administration of prednisolone reduces the risk of recurrent HELLP syndrome exacerbations."
|7.||Dacarbazine (DIC)FDA LinkGeneric
04/01/2011 - "In addition, HELLP syndrome can lead to rapidly developing, fulminant hyperfibrinolysis in the context of DIC. "
01/01/2009 - "HELLP syndrome may progress to DIC in 15-38% of patients. "
01/01/2009 - "We present a case of HELLP syndrome developed in 30 gestational week, complicated with DIC syndrome."
01/01/2009 - "[HELLP syndrome, complicated with DIC syndrome in the third trimester of pregnancy]."
10/01/2008 - "This article reports an initially mild HELLP syndrome case, with onset at week 26 and two days of pregnancy, where it was necessary to wait for the effectiveness of respiratory distress prophylaxis and, consequently, to carry out a close monitoring of the onset and worsening of DIC. "
01/01/1994 - "[Magnesium therapy in preeclampsia and HELLP syndrome--studies of pathophysiology]."
05/01/2006 - "[Elevated magnesium levels treated successfully in a woman with pre-eclampsia and HELLP syndrome]."
12/01/1991 - "Recent reports of clinical management for eclampsia, liver rupture, HELLP syndrome, severe PIH in the second trimester, severe hypertension, and magnesium toxicity are presented."
08/01/2000 - "Recent years have seen the introduction of the concepts of care in specialized units, expectant management of pre-eclampsia, conservative management of the HELLP syndrome (haemolysis, elevated liver enzymes, low platelets), usage of magnesium sulphate and improved feto-maternal surveillance. "
08/03/2002 - "A 34-year-old pregnant patient, admitted with severe pre-eclampsia and the 'haemolysis, elevated liver enzymes, low platelets' (HELLP) syndrome at 31 weeks gestational age, was treated with magnesium sulphate for imminent eclampsia. "
|9.||Betamethasone (Celestone)FDA Link
07/01/2009 - "Further investigation is required to assess the efficiency of betamethasone in management of HELLP syndrome."
07/01/2009 - "The effects of betamethasone treatment on clinical and laboratory features of pregnant women with HELLP syndrome."
07/01/2009 - "The betamethasone treatment has ended up with insignificant alterations in clinical outcomes and laboratory data of women with HELLP syndrome except beneficial effects on metabolic complications and need for platelet transfusion. "
12/01/2012 - "Here we can only urge further studies to provide frank evidence about the comparison of dexamethasone and betamethasone in HELLP syndrome. "
12/01/2012 - "Choice of glucocorticoid in HELLP syndrome - dexamethasone versus betamethasone: revisiting the dilemma."
05/01/2003 - "B) A risk for maternal survival caused by the embryo or fetal genetic constitution: autoimmune diseases of the mother generated by fetal antigens, some types of eclampsia with or without HELLP syndrome due to an immune or exaggerated inflammatory response of the mother, Ballantyne syndrome associated to eclampsia due to fetal-maternal genetic incompatibility, the classic fetus-maternal genetic incompatibility, embryo or fetus diseases caused by their genomic constitution, mainly hydatidiform mole and the triploid, or fetal cancer. "
01/01/2011 - "In the present study, we investigated plasma free TFPI antigen in four groups of women: healthy non-pregnant women without history of pregnancy complications; women at the beginning (<12 weeks) and women during the third trimester of a normal pregnancy; women with late pregnancy complications (pre-eclampsia / HELLP syndrome, intra-uterine fetal death, fetal growth retardation) at the time of obstetrical event and/or at distance from pregnancy. "
09/01/2003 - "We measured ADAMTS-13 and VWF (antigen, ristocetin cofactor activity, collagen binding, multimeric structure) in 17 pregnant women during HELLP syndrome and after 6 months during clinical remission. "
04/01/2015 - "Our study has found that postpartum use of plasma exchange therapy within 24 hours is an efficient and lifesaving treatment choice in Class I HELLP syndrome. "
04/01/2005 - "This study showed that postpartum early plasma exchange therapy improves treatment outcomes in patients with severe HELLP syndrome."
04/01/2005 - "The aim of this study was to investigate the effects of early postpartum use of plasma exchange in patients with HELLP syndrome on outcomes. "
04/01/2015 - "In this paper we presented the outcomes with the use of therapeutic plasma exchange in cases with class I HELLP syndrome. "
04/01/2015 - "A life-saving therapy in Class I HELLP syndrome: Therapeutic plasma exchange."
08/01/1997 - "The relationship between HELLP syndrome and CAPS is discussed, and possible pathogenetic mechanisms that explain the efficacy of repeated plasmapheresis in this setting are suggested. "
01/01/2014 - "Plasmapheresis can significantly improve the outcome of patients with HELLP syndrome who are unresponsive to conservative therapy."
01/01/2014 - "Plasmapheresis: Lifesaving treatment in severe cases of HELLP syndrome."
09/01/1999 - "Rarely, patients with refractory HELLP syndrome require plasmapheresis."
03/01/1994 - "[A case of HELLP syndrome with dramatic course successfully treated with early plasmapheresis]."
09/01/1993 - "Pregnant women with HELLP syndrome often require critical care nursing. "
02/01/2014 - "With the aim to identify how women's experiences of health services following severe maternal morbidity could be improved, we explored women's perceptions and experiences of severe maternal morbidity (defined as major obstetric haemorrhage, severe preeclampsia, eclampsia, HELLP syndrome, critical care unit admission) by synthesising evidence from qualitative studies. "
07/01/1986 - "Although patients with severe preeclampsia and eclampsia are infrequently admitted to critical care areas, it is important that the critical care nurse be aware of the HELLP syndrome. "
01/01/2000 - "Critical care of HELLP syndrome with corticosteroids."
12/01/2009 - "[Liver transplantation for subcapsular haematoma during HELLP Syndrome]."
01/01/2009 - "ABO incompatible liver transplantation as a bridge to treat HELLP syndrome."
10/01/2007 - "Liver transplantation for HELLP syndrome."
02/27/2006 - "In situ split liver transplantation using a donor with a recent history of HELLP syndrome."
02/01/2005 - "Patients with complicated HELLP syndrome are best managed at a center with expertise in liver transplantation."