|1.||Mulder, Barbara J M: 11 articles (10/2011 - 01/2005)|
|2.||Lechat, Philippe: 9 articles (04/2011 - 02/2002)|
|3.||Pieper, Petronella G: 8 articles (10/2011 - 10/2005)|
|4.||van Veldhuisen, Dirk J: 8 articles (07/2011 - 10/2005)|
|5.||Lainscak, Mitja: 7 articles (05/2014 - 09/2008)|
|6.||Meijboom, Folkert J: 7 articles (10/2011 - 06/2006)|
|7.||Follath, Ferenc: 7 articles (07/2011 - 06/2004)|
|8.||Krum, Henry: 7 articles (04/2011 - 11/2003)|
|9.||Düngen, Hans-Dirk: 6 articles (01/2014 - 09/2008)|
|10.||Inkrot, Simone: 6 articles (01/2014 - 09/2008)|
12/01/2005 - "Specifically, the Cardiac Insufficiency Bisoprolol Study II has shown a significant reduction in mortality and morbidity among patients with moderate to severe chronic heart failure treated with bisoprolol. "
01/01/2003 - "The use of bisoprolol was associated with significant improvement of heart failure functional class, lowering of heart rate (by 14%, p<0.01), elevation of systolic blood pressure (by 7.2+/-12.3 mm Hg, p<0.01) and increase of walking distance (by 30.1+/-29.0 m, p<0.01). "
09/01/2003 - "This is the first study in Spain to show that bisoprolol can be used effectively at the maximum recommended doses, for the outpatient treatment of heart failure."
12/15/2000 - "The use of bisoprolol in the therapy of chronic heart failure is not only clinically effective, it also saves net costs."
04/01/2013 - "The aim of the study was to develop a population pharmacokinetic (PK) model for clearance of bisoprolol in patients with congestive heart failure (CHF). "
|2.||Hypertension (High Blood Pressure)
01/01/2006 - "It has been reported that bisoprolol is effective in reducing blood pressure and has beneficial cardiac effects in patients with hypertension. "
11/01/2007 - "Data presented here indicate that bisoprolol 5 mg given once daily to treat patients with mild to moderate essential hypertension is effective and safe for treatment and for preservation of renal performance when given on a medium-term basis."
03/01/2013 - "Bisoprolol improved endothelial function and myocardium survival of hypertension with stable angina: a randomized double-blinded trial."
11/01/2015 - "rs12346562 had a similar trend in association with response to bisoprolol (a different β-blocker) in 207 Finnish men in the genetics of drug responsiveness in essential hypertension study. "
03/01/2013 - "222 subjects with hypertension who had received coronary angiography examination were involved in the study, 162 in bisoprolol therapy group (96 men, 59%) and 60 in non-bisoprolol group (39 men, 65%). "
01/01/1995 - "The Total Ischemic Burden Bisoprolol Study (TIBBS) was a randomized double-blind controlled study with two parallel groups; 330 patients from 30 centers in seven European countries with stable angina pectoris, a positive exercise test and more than two transient ischemic episodes during 48 h of Holter monitoring (central evaluation) were included. "
09/01/1993 - "Bisoprolol is suitable for use in hypertensive patients with associated diseases, in particular angina pectoris and impaired rhythm."
12/01/1987 - "Therefore, the effects of 5 and 10 mg bisoprolol and the duration of action were assessed in 12 patients (10 male, 2 female; mean age 60.2 years) with stable angina pectoris due to CHD after repeated administration. "
12/01/1987 - "Comparison of the effects of two doses of bisoprolol on exercise tolerance in exercise-induced stable angina pectoris."
01/01/1986 - "Measured by reduction in cardiac index, no appreciable increase in effect was achieved at bisoprolol plasma concentrations greater than 60 ng/ml. In angina pectoris patients, bisoprolol possesses the typical haemodynamic profile of a beta-adrenoceptor antagonist. "
|4.||Chronic Obstructive Pulmonary Disease (COPD)
01/01/2009 - "Bisoprolol is effective and safe drug in the treatment of stable angina combined with COPD. "
01/01/2007 - "Bisoprolol is well tolerated, effective and safe in COPD patients with IHD."
01/01/2012 - "We conclude that in this study on patients with IHD and COPD original bisoprolol demonstrated higher clinical efficacy and better tolerability than its generics."
01/01/2009 - "To study effects of a cardioselective beta-adrenoblocker bisoprolol on vascular wall endothelium and external respiration function in stable angina of effort combined with chronic obstructive pulmonary disease (COPD). "
07/15/2012 - "The magnitude of these effects was small and should not contraindicate the use of bisoprolol in patients with COPD."
|5.||Myocardial Ischemia (Ischemic Heart Diseases)
01/01/2011 - "Our patient was not on any medical treatment except for bisoprolol for ischemic heart disease. "
04/01/1994 - "Bisoprolol is a selective beta 1-adrenoceptor antagonist devoid of partial agonist activity that can be used for treatment of chronic and acute myocardial ischemia. "
01/01/2007 - "[Efficacy of a cardioselective beta1-adrenoblocker bisoprolol in patients with chronic obstructive pulmonary disease in combination with ischemic heart disease]."
01/01/2012 - "Generic preparation of bisoprolol according to a series of clinical studies can be successfully used both in patients with arterial hypertension and concomitant diseases and in patients with ischemic heart disease."
01/01/1997 - "In the Asymptomatic Cardiac Ischemia Pilot Study (ACIP) and Total Ischemic Burden Bisoprolol Study (TIBBS) trials, data suggest benefit from reducing myocardial ischemia. "
|6.||metoprolol succinate (Toprol-XL)
|7.||Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)
|3.||Coronary Artery Bypass (Coronary Artery Bypass Surgery)
|4.||Electric Countershock (Cardioversion)