|2.||Interstitial Lung Diseases (Interstitial Lung Disease)
|3.||Muscular Diseases (Myopathy)
|5.||Myositis (Idiopathic Inflammatory Myopathies)
|1.||Lundberg, Ingrid E: 17 articles (11/2014 - 04/2002)|
|2.||Miller, Frederick W: 15 articles (09/2014 - 08/2003)|
|3.||Rider, Lisa G: 13 articles (09/2014 - 11/2006)|
|4.||Alexanderson, Helene: 11 articles (11/2014 - 05/2004)|
|5.||Lundberg, I E: 8 articles (10/2015 - 10/2001)|
|6.||Miyasaka, Nobuyuki: 8 articles (07/2015 - 12/2003)|
|7.||Mimori, Tsuneyo: 8 articles (01/2015 - 09/2004)|
|8.||Oddis, Chester V: 8 articles (09/2014 - 12/2002)|
|9.||Targoff, Ira N: 8 articles (05/2014 - 10/2002)|
|10.||Shinjo, Samuel Katsuyuki: 7 articles (03/2015 - 02/2013)|
|1.||Cyclosporine (Ciclosporin)FDA LinkGeneric
04/01/2002 - "She achieved a second remission of polymyositis with cyclosporine, and has remained in remission for 4 years. "
04/01/2010 - "A suitably adapted treatment (association of corticotherapy and cyclosporine) improves polymyositis, and in most cases, a normal clinical state is achieved even if the symptoms were severe."
04/01/2002 - "She was diagnosed with polymyositis, and the dose of cyclosporine was increased. "
11/01/1991 - "Three patients with polymyositis refractory to conventional steroid and immunosuppressive treatment, but responsive to cyclosporin A, are described. "
01/01/1990 - "Polymyositis and cyclosporin A."
01/01/2008 - "Successful therapy with intravenous immunoglobulin in the management of polymyositis."
10/01/2010 - "Long-term efficacy of intravenously administered immunoglobulin in a case of polymyositis with limited application of steroid therapy."
02/01/2002 - "Results and long-term followup of intravenous immunoglobulin infusions in chronic, refractory polymyositis: an open study with thirty-five adult patients."
01/01/2014 - "High-dose subcutaneous immunoglobulins for the treatment of severe treatment-resistant polymyositis."
06/01/2001 - "In a patient with longstanding refractory polymyositis, intravenous (IV) immunoglobulin treatment was introduced at a standard dose (2 g/kg monthly). "
|3.||Adrenal Cortex Hormones (Corticosteroids)IBA
08/01/1996 - "HTLV-1-associated polymyositis can be successfully treated with corticosteroids."
05/01/2015 - "The aim of the study was to evaluate the effect of the prior use of corticosteroids (CS) on the presence of inflammatory infiltrates (InI) in muscle biopsies of polymyositis (PM). "
02/01/2000 - "Four patients were initially considered as having polymyositis; corticosteroids and immunosuppressive drugs were always inefficient. "
01/01/1999 - "Four years after presentation, he developed polymyositis which was completely controlled with short courses of corticosteroids. "
06/01/1995 - "A 55-year-old woman had received corticosteroids for the treatment of polymyositis for six years. "
|4.||Tacrolimus (Prograf)FDA LinkGeneric
07/01/2009 - "Tacrolimus--a potential therapy for polymyositis?"
02/01/2005 - "There is possibility that tacrolimus becomes one of the choices of the treatment of polymyositis."
02/01/2005 - "[Effectiveness of tacrolimus in a case of polymyositis]."
10/15/2014 - "Polymyositis in solid organ transplant recipients receiving tacrolimus."
12/01/2015 - "The efficacy of tacrolimus in patients with refractory dermatomyositis/polymyositis: a systematic review."
|5.||Intravenous Immunoglobulins (IVIG)FDA Link
02/01/2002 - "IVIG is an interesting therapy for the treatment of polymyositis, with results showing that the condition of approximately 70% of the patients tested improved. "
02/01/2002 - "We carried out an open, prospective study to evaluate the efficacy of IVIG in subjects with polymyositis that was refractory to traditional treatments, and we evaluated the benefits of this therapy over a long-term period of followup. "
05/01/1996 - "In some patients with polymyositis, IVIG is reported to be of benefit but controlled studies have not yet been completed. "
01/01/2016 - "SSc patients with overlap polymyositis who remained active and unresponsive to conventional disease-modifying agents and who subsequently received IVIG were identified. "
01/01/2014 - "Intravenous immunoglobulins (IVIg) are thus recommended for patients with drug-resistant polymyositis. "
|6.||Prednisolone (Predate)FDA LinkGeneric
11/01/2005 - "The polymyositis improved promptly after the administration of prednisolone and remains in remission with a current maintenance program of prednisolone 5 mg/day."
01/01/2012 - "Long-term outcome of polymyositis treated with high single-dose alternate-day prednisolone therapy."
01/01/2008 - "She was diagnosed with polymyositis (PM) on the basis of the histological findings of muscle biopsy and treated with prednisolone. "
01/01/2007 - "A 53-year-old man was diagnosed with polymyositis (PM) in 1997 and treated with prednisolone. "
11/01/2005 - "Prednisolone 50 mg/day as an initial dose was started for the polymyositis following which the prednisolone dose was gradually tapered off. "
|7.||Azathioprine (Imuran)FDA LinkGeneric
01/01/2015 - "Case 3-31 years old with polymyositis, treated with azathioprine for 3 years with complete remission of the disease, took the informed decision to get pregnant after medical consultation and full weaning from azathioprine, and gave birth to a healthy term new-born. "
03/01/1980 - "A controlled, prospective, double-blind, therapeutic trial of azathioprine was conducted in the initial therapy of polymyositis. "
01/01/2015 - "We concluded there is uncertainty if azathioprine improves or not muscular strength in polymyositis because the certainty of the evidence is very low. "
09/01/1994 - "Therapy-related acute myeloid leukaemia following immunosuppression with azathioprine for polymyositis."
10/01/1973 - "Azathioprine therapy in polymyositis."
06/01/1994 - "Endomycardial, bone marrow and skeletal muscle biopsies and the pericardial fluid showed a marked eosinophilic infiltration or polymyositis, respectively, which could be treated successfully with steroids and azathioprin. "
05/01/1994 - "The patient was given the diagnosis of orbital polymyositis and her condition improved clinically and radiographically while taking parenteral steroids. "
11/01/2014 - "Upon tapering of steroids, the patient experienced a relapse of polymyositis. "
11/01/2012 - "Typically occurring in patients greater than 50 years of age, it is commonly misdiagnosed as polymyositis or other rheumatological disease and is often ineffectively treated with steroids . "
01/01/2008 - "It is frequently misdiagnosed as polymyositis and wrongly treated with steroids.3 The typical symptoms and signs are illustrated by a recent case which presented to our department (see box 1)."
|9.||Methotrexate (Mexate)FDA LinkGeneric
09/01/1993 - "We may conclude that IVCY and low-dose weekly methotrexate together could be an alternative in refractory polymyositis."
11/01/1973 - "Methotrexate therapy in polymyositis."
01/02/1971 - "Treatment of corticosteroid-resistant polymyositis with methotrexate."
04/01/1995 - "The objective of this study was to evaluate the efficacy of low-dose oral methotrexate (MTX) in improving muscle strength and reducing the corticosteroid requirement of patients with polymyositis (PM) and dermatomyositis (DM). "
05/01/1995 - "Polymyositis and chronic graft-versus-host disease: efficacy of intravenous gammaglobulin and methotrexate."
12/01/2014 - "Inflammatory cells that surround, invade and destroy healthy muscle fibers expressing MHC class I antigen are the typical pathological finding of polymyositis. "
07/01/2008 - "Polymyositis and sIBM showed MHC class I antigen positivity along sarcolemma of single and small groups of muscle fibers. "
10/01/1992 - "Muscle fibers strongly expressed the major histocompatibility complex class I antigen (2/2) as in polymyositis. "
01/01/2009 - "Remarkably, MHC-I antigen was expressed in the muscle membrane and most of the inflammatory cells were CD8-positive, suggesting that class-I antigen-dependent cytotoxic T-cells played a crucial role in the muscle pathology, which supported a diagnosis of polymyositis rather than dermatomyositis. "
01/01/1988 - "The amino acid sequence of histidyl-tRNA synthetase, the Jo-I antigen of polymyositis, has been compared with that of the polyprotein of encephalomyocarditis virus (EMCV), an agent shown recently to produce polymyositis symptoms in mice. "
01/01/2014 - "The findings herein suggest that a combined aerobic and strength training program may be tolerable and potentially effective in improving muscle function, aerobic conditioning, and quality of life in patients with persistent active polymyositis."
06/15/2005 - "Safety and efficacy of submaximal eccentric strength training for a subject with polymyositis."
01/01/2014 - "Our aim was to evaluate the safety and efficacy of a low-intensity resistance training program combined with partial blow flow restriction (BFR training) in a cohort of patients with polymyositis (PM) and dermatomyositis (DM). "
03/01/2012 - "For patients with polymyositis and dermatomyositis a few studies have reported reduced clinical disease activity after resistance training in patients with chronic phase of disease. "
01/01/2014 - "Safety and possible effects of low-intensity resistance training associated with partial blood flow restriction in polymyositis and dermatomyositis."
07/01/1997 - "The characteristic findings of pulmonary involvement in polymyositis (PM) or dermatomyositis (DM) and the change in findings before and after treatment were evaluated with sequential high-resolution CT studies. "
01/01/2012 - "To investigate peripheral blood lymphocyte subpopulations, particularly helper T (Th) cells and cytokine expression before and after treatment in polymyositis (PM) and dermatomyositis (DM). "
04/01/1988 - "Polymyositis, however, has never been reported immediately after treatment for active hyperthyroidism. "
08/29/1992 - "Moreover, the fact that the abnormalities observed disappeared after treatment suggests that phosphorus NMR spectroscopy could be used as a non-invasive method in the follow-up of polymyositis, but this must be confirmed by further studies."
03/01/2013 - "We report one case of dermatomyositis and one of polymyositis refractory to several conventional inmunosupressive therapies, which present a response after treatment with rituximab, enabling steroid dose reduction and a prolonged remission."
12/01/2015 - "There are few data in the literature supporting the efficacy of plasma-exchange in dermato/polymyositis. "
12/01/2015 - "Our findings suggest that plasma-exchange in association with immunosuppressant agents could play a relevant role in the management of dermato/polymyositis in acute phase. "
12/01/2015 - "Plasma-exchange as a "rescue therapy" for dermato/polymyositis in acute phase. "
01/01/1982 - "The role of plasma exchange in treatment of idiopathic polymyositis."
05/21/1992 - "Controlled trial of plasma exchange and leukapheresis in polymyositis and dermatomyositis."
|4.||Drug Therapy (Chemotherapy)
10/15/1995 - "We then present a small simulation study to compare different transforms for setting confidence limits, and provide an illustration of our approach in an observational study of drug therapy of polymyositis."
05/01/2015 - "Whereas polymyositis responds to immunosuppressant drug therapy, sIBM responds poorly, if at all. "
03/01/2011 - "A female patient with polymyositis was initially treated with pharmacotherapy. "
05/01/1989 - "Rarely, polymyositis and scleroderma-like syndromes have been associated with drug therapy. "
09/01/1982 - "Plasmapheresis and immunosuppressive drug therapy in polymyositis."
03/14/2000 - "We also found enhanced alphaBC in abnormal fibers in other diseases; X fibers, however, were extremely sparse or absent, except in two atypical cases of polymyositis refractory to immunotherapy. "
11/01/1991 - "The above data indicate considerable improvement of the prospects of these diseases, whereby the more than treble prolongation of survival of patients as compared with the previous period is due to effective, although not causal immunotherapy, in particular in systemic lupus erythematosus and dermato- and polymyositis."
12/01/2015 - "Our objective was to systematically review the evidence for immunotherapy in the treatment of dermatomyositis and polymyositis. "
12/01/2015 - "The evidence for immunotherapy in dermatomyositis and polymyositis: a systematic review."
02/01/2013 - "Dermatomyositis and polymyositis: from immunopathology to immunotherapy (immunobiologics)."