A histamine H2 receptor agonist that is often used to study the activity of histamine and its receptors.
Also Known As:
Dimaprit Dihydrochloride; Dimaprit Maleate (1:1); Dihydrochloride, Dimaprit; Carbamimidothioic acid, 3-(dimethylamino)propyl ester
Networked: 50 relevant articles (1 outcomes, 3 trials/studies)

Relationship Network

Bio-Agent Context: Research Results


1. Singh, J: 2 articles (03/2011 - 07/2002)
2. Chandranath, S I: 2 articles (03/2011 - 07/2002)
3. Bastaki, S M A: 2 articles (03/2011 - 07/2002)
4. Erfanparast, Amir: 1 article (10/2015)
5. Dabaghi, Milad: 1 article (10/2015)
6. Tamaddonfard, Esmaeal: 1 article (10/2015)
7. Taati, Mina: 1 article (10/2015)
8. Adem, A: 1 article (03/2011)
9. D'Souza, A: 1 article (03/2011)
10. Hasanein, Parisa: 1 article (02/2011)

Related Diseases

1. Shock
2. Hepatitis
3. Ulcer
09/01/1987 - "4 Famotidine reduced, in a dose-dependent manner, ulcer incidence in stomachs of dimaprit-treated rats and in duodena of cysteamine-treated animals with a potency respectively 2 and 7 times higher than that of ranitidine. "
09/01/1988 - "Conversely, verapamil only slightly attenuates dimaprit-stimulated gastric acid secretion and exacerbates ethanol-induced gastric ulcers; its anti-stress ulcer effects are only partially attenuated by indomethacin. "
07/01/2002 - "This study investigates the effects of epidermal growth factor (EGF), urogastrone (UG) and transforming growth factor-alpha (TGFalpha) and its derivative on dimaprit- and pentagastrin-induced gastric acid secretion and on acidified ethanol (AE)-evoked ulcer formation in anaesthetized rats. "
09/01/1988 - "We now show that DPPE profoundly inhibits restraint and cold stress and ethanol-induced gastric ulcer formation, accelerates ulcer healing, attenuates the stress-induced rise in plasma corticosterone level, and significantly reduces basal and H2 agonist (dimaprit)-stimulated and, to a lesser extent, bethanechol-stimulated gastric acid output in conscious rats. "
02/01/2008 - "The study investigated the anti-secretory and anti-ulcer effects of esomeprazole, the S-isomer of omeprazole on dimaprit, histamine and dibutyryl adenosine 3, 5 cyclic monophosphate (dbcAMP)-evoked gastric acid secretion, acidified ethanol (AE) and indomethacin (INDO)-induced haemorrhagic lesions and on prostaglandin E2 (PGE2) level in the rat in vivo and rabbit in vitro preparations. "
4. Cholestasis
5. Gastric Fistula

Related Drugs and Biologics

1. Histamine Agonists
2. Histamine (Histamine Dihydrochloride)
3. Ethanol (Ethyl Alcohol)
4. Cimetidine (Biomet)
5. Pentagastrin (Peptavlon)
6. Indomethacin (Indometacin)
7. Omeprazole (Esomeprazole)
8. zolantidine
9. Transforming Growth Factor alpha (TGF-alpha)
10. Dinoprostone (PGE2)

Related Therapies and Procedures

1. Ligation
2. Injections