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Neurofibromatoses (Neurofibromatosis)

A group of disorders characterized by an autosomal dominant pattern of inheritance with high rates of spontaneous mutation and multiple neurofibromas or neurilemmomas. NEUROFIBROMATOSIS 1 (generalized neurofibromatosis) accounts for approximately 95% of cases, although multiple additional subtypes (e.g., NEUROFIBROMATOSIS 2, neurofibromatosis 3, etc.) have been described. (From Neurochirurgie 1998 Nov;44(4):267-72)
Also Known As:
Neurofibromatosis; Syndrome, Neurofibromatosis; Multiple Neurofibromas; Neurofibromatosis 3; Neurofibromatosis Syndrome; Multiple Neurofibroma; Neurofibroma, Multiple; Neurofibromas, Multiple; Neurofibromatosis 3s; Neurofibromatosis Syndromes; Neurofibromatosis Type 3s; Syndromes, Neurofibromatosis; Type 3, Neurofibromatosis; Neurofibromatosis Type 3
Networked: 796 relevant articles (13 outcomes, 36 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Neoplasms (Cancer)
2. Acoustic Neuroma (Acoustic Neurinoma)
3. Neurocutaneous Syndromes (Phakomatoses)
4. Sturge-Weber Syndrome (Sturge-Kalischer-Weber Syndrome)
5. von Hippel-Lindau Disease (von Hippel Lindau Disease)

Experts

1. Plotkin, Scott R: 14 articles (03/2014 - 10/2005)
2. Gutmann, David H: 8 articles (04/2015 - 11/2002)
3. Fisher, Michael J: 7 articles (04/2015 - 06/2012)
4. Ratner, Nancy: 7 articles (03/2014 - 11/2002)
5. Dombi, Eva: 6 articles (04/2015 - 01/2013)
6. Giovannini, Marco: 6 articles (03/2014 - 04/2003)
7. Widemann, Brigitte C: 5 articles (04/2015 - 11/2013)
8. Ferner, Rosalie E: 5 articles (02/2015 - 02/2010)
9. Morrison, Helen: 5 articles (03/2014 - 02/2010)
10. Mautner, Victor-Felix: 5 articles (02/2014 - 08/2004)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Neurofibromatoses:
1. Gadolinium DTPA (Magnevist)FDA Link
2. Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link
3. bevacizumabFDA Link
4. Calcitonin Gene-Related Peptide Receptors (Calcitonin-Gene Related Peptide Receptor)IBA
5. Monophenol Monooxygenase (Tyrosinase)IBA
6. SchwannomatosisIBA
7. DNA (Deoxyribonucleic Acid)IBA
8. Biological Markers (Surrogate Marker)IBA
9. Neurofibromin 1 (Neurofibromin)IBA
10. Lynch cancer family syndrome 2IBA

Therapies and Procedures

1. Drug Therapy (Chemotherapy)
2. Molecular Targeted Therapy
3. Transplantation (Transplant Recipients)
4. Blepharoplasty
5. Therapeutics