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CD3 Complex

Complex of at least five membrane-bound polypeptides in mature T-lymphocytes that are non-covalently associated with one another and with the T-cell receptor (RECEPTORS, ANTIGEN, T-CELL). The CD3 complex includes the gamma, delta, epsilon, zeta, and eta chains (subunits). When antigen binds to the T-cell receptor, the CD3 complex transduces the activating signals to the cytoplasm of the T-cell. The CD3 gamma and delta chains (subunits) are separate from and not related to the gamma/delta chains of the T-cell receptor (RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA).
Also Known As:
CD3 Antigen; T3 Antigen; T3 Complex; Antigen, CD3; Antigen, T3; Antigens, T3; Antigens, CD3; CD3 Antigens; T3 Antigens
Networked: 147 relevant articles (0 outcomes, 9 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Schlereth, Bernd: 3 articles (10/2009 - 04/2007)
2. Seimetz, Diane: 2 articles (01/2011 - 10/2010)
3. Brischwein, Klaus: 2 articles (10/2009 - 01/2008)
4. Baeuerle, Patrick A: 2 articles (01/2008 - 04/2007)
5. Kufer, Peter: 2 articles (01/2008 - 04/2007)
6. Lutterbuese, Petra: 2 articles (01/2008 - 04/2007)
7. Lutterbuese, Ralf: 2 articles (01/2008 - 04/2007)
8. Alroy, Joseph: 2 articles (01/2005 - 01/2003)
9. Cousineau, Isabelle: 1 article (01/2022)
10. Dagenais, Michel: 1 article (01/2022)

Related Diseases

1. Lymphoma (Lymphomas)
2. Hyperplasia
3. Carcinoma (Carcinomatosis)
4. Systemic Lupus Erythematosus (Libman-Sacks Disease)
5. Acute Myeloid Leukemia (Acute Myelogenous Leukemia)

Related Drugs and Biologics

1. T-Cell Antigen Receptors (T-Cell Receptor)
2. Antigens
3. Monoclonal Antibodies
4. Antibodies
5. Histocompatibility Antigens Class II
6. Glycoproteins (Glycoprotein)
7. CD56 Antigen
8. Bispecific Antibodies
9. Epithelial Cell Adhesion Molecule
10. Proteins (Proteins, Gene)

Related Therapies and Procedures

1. Therapeutics
2. Immunotherapy
3. Drug Therapy (Chemotherapy)
4. Biological Therapy