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Advanced Glycosylation End Products

Products derived from the nonenzymatic reaction of glucose and proteins in vivo that exhibit a yellow-brown pigmentation and an ability to participate in protein-protein cross-linking. These substances are involved in biological processes relating to protein turnover and it is believed that their excessive accumulation contributes to the chronic complications of diabetes mellitus.
Also Known As:
Glycosylation End Products, Advanced; Advanced Glycation End Products; Glycation End Products, Advanced
Networked: 2322 relevant articles (22 outcomes, 156 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Yamagishi, Sho-ichi: 81 articles (05/2015 - 06/2002)
2. Takeuchi, Masayoshi: 74 articles (12/2015 - 06/2002)
3. Matsui, Takanori: 61 articles (05/2015 - 03/2006)
4. Yamagishi, S: 39 articles (08/2015 - 08/2000)
5. Schmidt, Ann Marie: 38 articles (10/2014 - 02/2002)
6. Takeuchi, M: 30 articles (05/2015 - 01/2001)
7. Cooper, Mark E: 28 articles (01/2014 - 09/2002)
8. Yamagishi, Sho-Ichi: 26 articles (12/2015 - 02/2003)
9. Schalkwijk, Casper G: 26 articles (08/2015 - 01/2002)
10. Vlassara, Helen: 26 articles (05/2015 - 07/2002)

Related Diseases

1. Inflammation
2. Diabetic Nephropathies (Diabetic Nephropathy)
3. Chronic Kidney Failure (Chronic Renal Failure)
4. Diabetic Angiopathies (Diabetic Angiopathy)
5. Atherosclerosis

Related Drugs and Biologics

1. Nitric Oxide (Nitrogen Monoxide)
2. pentosidine
3. Ligands
4. polyol
5. pimagedine (aminoguanidine)
6. Calcium
7. Angiotensin II
8. 4-hydroxy-2-nonenal (4-hydroxynonenal)
9. iodonitrotetrazolium (INT)
10. Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)

Related Therapies and Procedures

1. Renal Dialysis (Hemodialysis)
2. Peritoneal Dialysis
3. Continuous Ambulatory Peritoneal Dialysis (CAPD)
4. Transplants (Transplant)
5. Artificial Respiration (Mechanical Ventilation)