Low Back Pain (Lumbago)

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2039 relevant articles (260 outcomes, 426 trials/studies) found for this Disease

Description: Acute or chronic pain in the lumbar or sacral regions, which may be associated with musculo-ligamentous SPRAINS AND STRAINS; INTERVERTEBRAL DISK DISPLACEMENT; and other conditions.

Also Known As:

Lumbago; Lower Back Pain; Mechanical Low Back Pain; Back Pain, Low; Low Back Ache; Low Back Pain, Mechanical; Low Back Pain, Posterior Compartment; Low Back Pain, Postural; Low Back Pain, Recurrent; Low Backache; Postural Low Back Pain; Recurrent Low Back Pain; Ache, Low Back; Aches, Low Back; Back Ache, Low; Back Aches, Low; Back Pain, Lower; Back Pains, Low; Back Pains, Lower; Backache, Low; Backaches, Low; Low Back Aches; Low Back Pains; Low Backaches; Lower Back Pains; Pain, Low Back; Pain, Lower Back; Pains, Low Back; Pains, Lower Back

Relationship Network

Disease Context: Research Results

Nervous System Diseases: 3406

Neurologic Manifestations: 2876

Pain: 68606

Back Pain: 1485

Low Back Pain: 2039

Signs and Symptoms Pathological Conditions

Neurologic Manifestations: 2876

Pain: 68606

Back Pain: 1485

Low Back Pain: 2039

Related Diseases

1.	Pain (Aches)
2.	Syndrome
3.	Osteoarthritis
4.	Sciatica (Sciatic Neuralgia)
5.	Neck Pain (Cervicalgia)
289 Diseases and 835 more articles analyzed in the Full Patient-Physician Summary Report, order at left...

Experts

1.	van Tulder, M W: 7 articles (01/2008 - 01/2000)
2.	Fritz, Julie M: 7 articles (12/2007 - 02/2004)
3.	Latimer, Jane: 6 articles (11/2007 - 01/2002)
4.	Childs, John D: 6 articles (11/2006 - 02/2004)
5.	Brosseau, Lucie: 5 articles (01/2008 - 03/2002)
6.	Jabbari, Bahman: 5 articles (10/2007 - 11/2002)
7.	Maher, Christopher G: 5 articles (09/2007 - 01/2002)
8.	van Tulder, Maurits W: 5 articles (01/2007 - 05/2005)
9.	Flynn, Timothy W: 5 articles (11/2006 - 02/2004)
10.	Furlan, Andrea D: 4 articles (01/2008 - 09/2002)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Low Back Pain:

1.	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 07/15/2008 - "There is strong evidence that various types of NSAIDs, including COX-2 NSAIDs, are equally effective for acute low back pain" 01/01/2008 - "There is strong evidence that various types of NSAIDs, including COX-2 NSAIDs, are equally effective for acute low-back pain" 01/01/2006 - "There is strong evidence (level 1) that various types of NSAIDs are equally effective for acute low back pain" 07/29/2000 - "There was strong evidence that advice to stay active, non-steroidal anti-inflammatory drugs (NSAIDs) and muscle relaxants were effective in acute low back pain" 01/01/2000 - "There is strong evidence (level 1) that various types of NSAIDs are equally effective for acute low back pain" Get all the results and reference details, order at left...
2.	Acetaminophen (Paracetamol)FDA LinkGeneric 11/01/2008 - "There is insufficient evidence to assess the efficacy of paracetamol in patients with low back pain" 11/01/2008 - "There is a clear need for large, high quality randomized controlled trials evaluating paracetamol, to provide reliable evidence of paracetamol's effectiveness in patients with low back pain and to establish the validity of the recommendations in clinical guidelines." 11/01/2008 - "Trials were eligible if they were randomized controlled trials comparing paracetamol to no treatment, placebo or another treatment in patients with non-specific low back pain" 11/01/2008 - "A systematic review of paracetamol for non-specific low back pain." 08/01/2008 - "In addition, these drugs have not been proven to be superior to acetaminophen or nonsteroidal anti-inflammatory drugs for low back pain" Get all the results and reference details, order at left...
3.	Diclofenac (SR 38)FDA LinkGeneric 03/01/2007 - "with a second dose on day 1) provides effective relief for acute low back pain, and was at least as efficacious as diclofenac 75 mg b.i.d., with a nonsignificant but numerically lower incidence of gastrointestinal adverse events." 01/01/2007 - "METHODS: A randomised, double-blind, parallel, active controlled, multicentre study that included 370 outpatients with acute low back pain was conducted to compare the analgesic efficacy of dexketoprofen 50mg twice daily versus diclofenac 75mg twice daily administered intramuscularly for 2 days" 01/01/2007 - "A multicentre, randomised, double-blind study comparing the efficacy and tolerability of intramuscular dexketoprofen versus diclofenac in the symptomatic treatment of acute low back pain." 03/01/2006 - "Before this hospitalization, he had received a 2-week course of oral diclofenac sodium 25 mg TID for low back pain" 11/01/2001 - "A 38-year-old nurse treated herself for acute lower back pain with 100 mg diclofenac intramuscularly" Get all the results and reference details, order at left...
4.	Tramadol FDA LinkGeneric 03/01/2000 - "CONCLUSION: Among patients who tolerated it well, tramadol was effective for the treatment of chronic low back pain." 03/01/2008 - "BACKGROUND: This study evaluated the safety and efficacy of tramadol ER 300 mg and 200 mg versus placebo once daily in the treatment of chronic low back pain, using an open-label run-in followed by, without washout, a randomized controlled study design" 12/01/2000 - "Efficacy of tramadol in treatment of chronic low back pain." 03/01/2000 - "Efficacy of tramadol in treatment of chronic low back pain." 01/01/2006 - "Tramadol SR 100 mg capsules administered twice daily had equivalent efficacy to tramadol IR 50 mg capsules administered four times daily in the treatment of moderate to severe chronic low back pain in a well designed study" Get all the results and reference details, order at left...
5.	PlacebosIBA 12/01/2001 - "CONCLUSIONS: Manipulation and mobilization are more effective for chronic low back pain than placebos or usual care for up to 6 months (level 2)" 09/01/2007 - "Prospective, randomized, single-blind, sham treatment-controlled study of the safety and efficacy of an electromagnetic field device for the treatment of chronic low back pain: a pilot study." 07/01/2008 - "Taken together, these results demonstrate that imperfect placebos are common in low back pain trials; a result suggesting that many trials provide potentially biased estimates of treatment efficacy" 07/01/2008 - "Imperfect placebos are common in low back pain trials: a systematic review of the literature." 12/01/1998 - "The control group received a sham treatment of six exercises shown to be ineffective in reducing low back pain" Get all the results and reference details, order at left...
6.	etoricoxibIBA 08/01/2003 - "We evaluated etoricoxib, a novel COX-2-specific inhibitor, in 319 patients with chronic low back pain (LBP) in this double-blind, placebo-controlled trial" 05/01/2003 - "Data on etoricoxib efficacy in chronic low back pain is beginning to emerge" 08/01/2003 - "Treatment of chronic low back pain with etoricoxib, a new cyclo-oxygenase-2 selective inhibitor: improvement in pain and disability--a randomized, placebo-controlled, 3-month trial." 01/01/2004 - "Etoricoxib reduced pain and disability and improved quality of life in patients with chronic low back pain: a 3 month, randomized, controlled trial." 03/01/2008 - "Correlation of measures of pain, function, and overall response: results pooled from two identical studies of etoricoxib in chronic low back pain." Get all the results and reference details, order at left...
7.	salicylhydroxamic acid (SHAM)IBA 07/01/2004 - "OBJECTIVE: To compare the relative efficacy of chiropractic adjustments with muscle relaxants and placebo/sham for subacute low back pain" 06/01/2008 - "Acupuncture for acute non-specific low back pain: a pilot randomised non-penetrating sham controlled trial." 04/19/2005 - "STUDY SELECTION: Randomized, controlled trials comparing needle acupuncture with sham acupuncture, other sham treatments, no additional treatment, or another active treatment for patients with low back pain" 10/01/2002 - "This prospective, randomised controlled trial, with three parallel groups, patient and observer blinded for verum and sham acupuncture and a follow up of 3 months raises the question: "Does a combination of acupuncture and conservative orthopedic treatment improve conservative orthopedic treatment in chronic low back pain (LBP)" 01/01/2000 - "There was limited evidence from eight trials that acupuncture is not more effective than placebo or sham acupuncture for the treatment of chronic low back pain" Get all the results and reference details, order at left...
8.	Lidocaine (Xylocaine)FDA LinkGeneric 04/30/1991 - "For the treatment of acute low back pain, lidocaine administered alone is adequately effective in most cases, and is well tolerated." 12/01/2002 - "Prospective, controlled clinical trials are planned to further evaluate the efficacy and safety of the lidocaine patch for treatment of chronic low back pain with or without a neuropathic component." 07/01/2005 - "This prospective, 6-week, multicenter, open-label, nonrandomized pilot study was designed to assess the effectiveness and safety of a lidocaine patch 5% in patients with low back pain (LBP)" 07/01/2005 - "Lidocaine patch treatment in patients with low back pain: results of an open-label, nonrandomized pilot study." 12/01/2002 - "CONCLUSIONS: Based on our experience with the four cases presented here and with other patients in our clinic, we believe that addition of the lidocaine patch 5% to the analgesic regimen in chronic low back pain may be beneficial" Get all the results and reference details, order at left...
9.	Morphine (MS Contin)FDA LinkGeneric 05/01/2006 - "DESIGN: We conducted a double-blind, placebo-controlled, randomized, crossover-designed trial of intravenous morphine vs. placebo in 60 subjects with chronic low back pain and discogenic abnormalities" 09/01/1997 - "CLINICAL PRESENTATION: We report a complication that occurred in a 48-year-old woman who presented with intractable lower back pain 18 months after morphine pump implantation" 03/01/2005 - "We present an individual with chronic low back pain who was treated with an implanted morphine pump, which provided very good pain relief for 16 mos" 02/01/2008 - "PATIENTS AND METHODS: Reticulated and pigmented telangiectasic erythema was observed at the morphine pump implantation site in a 56-year-old man presenting chronic lower back pain" 01/01/1992 - "Several studies in humans report that spinal steroids are effective in the treatment of chronic low-back pain when given in combination with morphine" Get all the results and reference details, order at left...
10.	Opioid Analgesics (Opioids)IBA 01/01/2008 - "Evidence-informed management of chronic low back pain with opioid analgesics." 01/01/2007 - "BACKGROUND: The use of opioids in the long-term management of chronic low-back pain (LBP) appears to be increasing" 01/01/2005 - "PERSPECTIVE: Definitive studies of long-acting opioids in patients with chronic low back pain are lacking" 12/01/2008 - "Patient race and physicians' decisions to prescribe opioids for chronic low back pain." 01/01/2007 - "BACKGROUND: Some patients with long-standing low back pain will benefit from treatment with strong opioids" Get all the results and reference details, order at left...
485 Drugs and Important Bio-Agents and 1004 more articles analyzed in the Full Patient-Physician Summary Report, order at left...

Therapies and Procedures

1.	Spinal Manipulation 02/01/1999 - "Based on the most recent and comprehensive systematic reviews, there is moderate evidence of short-term efficacy for spinal manipulation in the treatment of both acute and chronic low back pain" 05/01/2005 - "BACKGROUND CONTEXT: Spinal manipulation (SM) is an effective treatment for low back pain (LBP), and it has been theorized that SM induces a beneficial neurophysiological effect by stimulating mechanically sensitive neurons in the lumbar facet joint capsule (FJC)" 02/01/1994 - "These nerve impingements are postulated to be the result of misaligned vertebra or "subluxations." Research indicates that spinal manipulation may be beneficial in low back pain, but the claim that spinal manipulation is of value for optimizing general health and treating non-musculoskeletal conditions is unfounded." 02/01/1982 - "Three criteria of reliability and validity were used: (1) significant agreement between independent observers, (2) significantly different scores in the groups with and without low back pain, and (3) significant improvement following a successful spinal manipulation" 07/01/2007 - "OBJECTIVE: Spinal manipulation therapy is widely used for the treatment of lower-back pain" Get all the results and reference details, order at left...
2.	Musculoskeletal Manipulations (Manipulative Therapy) 11/01/2005 - "DISCUSSION: Manual therapy with specific adjuvant exercise appears to be beneficial in treating chronic low back pain" 01/01/2004 - "REVIEWER'S CONCLUSIONS: There is no evidence that spinal manipulative therapy is superior to other standard treatments for patients with acute or chronic low-back pain." 06/03/2003 - "CONCLUSIONS: There is no evidence that spinal manipulative therapy is superior to other standard treatments for patients with acute or chronic low back pain." 04/01/1992 - "Chiropractors suggest that manipulation therapy is cost effective for treatment of low back pain in comparison with therapies given by physicians." 07/01/2008 - "We performed a pre-planned secondary analysis of a randomised controlled trial investigating the efficacy of spinal manipulative therapy in 239 patients presenting to general practice clinics for acute, non-specific, low back pain" Get all the results and reference details, order at left...
3.	Exercise Therapy (Therapy, Exercise) 08/01/2006 - "Exercise therapy has limited value for acute low back pain, but strong evidence supports exercise therapy in the management of chronic low back pain" 11/01/2000 - "There is strong evidence that exercise therapy is not more effective for acute low back pain than inactive or other active treatments with which it has been compared" 06/01/2001 - "CONCLUSION: Long-term results suggest that specific exercise therapy in addition to medical management and resumption of normal activity may be more effective in reducing low back pain recurrences than medical management and normal activity alone." 05/03/2005 - "In acute low back pain populations, exercise therapy is as effective as either no treatment or other conservative treatments." 01/01/2005 - "In acute low-back pain, exercise therapy is as effective as either no treatment or other conservative treatments." Get all the results and reference details, order at left...
4.	Transcutaneous Electric Nerve Stimulation (TENS) 09/30/1993 - "Recent data suggest that subthreshold TENS is no effective treatment for low back pain" 04/01/1991 - "Therapeutic controversies continue concerning the efficacy of chiropractic intervention and transcutaneous electric nerve stimulation for low back pain patients" 07/01/2005 - "OBJECTIVE: To evaluate the efficacy of paramedic-administered TENS in patients with acute low back pain during emergency transport" 05/01/2003 - "OBJECTIVES: To determine the efficacy of a complementary analgesic modality, percutaneous electrical nerve stimulation (PENS), for the treatment of chronic low back pain (CLBP) in community-dwelling older adults" 05/01/2003 - "Efficacy of percutaneous electrical nerve stimulation for the treatment of chronic low back pain in older adults." Get all the results and reference details, order at left...
5.	Traction 12/01/1984 - "Use of a randomized single-blind technique significantly improved chronic cases of lumbago by a new traction treatment called auto-traction" 12/16/1995 - "Our data do not support the claim that traction is effective for patients with low back pain." 01/01/2008 - "Evidence-informed management of chronic low back pain with traction therapy." 12/15/2007 - "OBJECTIVE: To identify a subgroup of patients with low back pain who are likely to respond favorably to an intervention including mechanical traction" 03/01/2003 - "The literature on the efficacy of traction in the treatment of low back pain (LBP) is conflicting" Get all the results and reference details, order at left...
151 Therapies and Procedures and 1148 more articles analyzed in the Full Patient-Physician Summary Report, order at left...

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