Kidney Failure (Renal Failure)

Subscribe to Selected New Research on Kidney Failure

14067 relevant articles (647 outcomes, 898 trials/studies) found for this Disease

Description: A severe irreversible decline in the ability of kidneys to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism. Renal failure, either acute (KIDNEY FAILURE, ACUTE) or chronic (KIDNEY FAILURE, CHRONIC), requires HEMODIALYSIS.

Also Known As:

Renal Failure; Failure, Kidney; Failure, Renal; Failures, Kidney; Failures, Renal; Kidney Failures; Renal Failures

Relationship Network

Disease Context: Research Results

Male Urogenital Diseases

Urologic Diseases: 395

Kidney Diseases: 5158

Renal Insufficiency: 5313

Kidney Failure: 14067

Chronic Kidney Failure: 20156

Acute Kidney Failure: 7878

Female Urogenital Diseases and Pregnancy Complications

Female Urogenital Diseases

Urologic Diseases: 395

Kidney Diseases: 5158

Renal Insufficiency: 5313

Kidney Failure: 14067

Chronic Kidney Failure: 20156

Acute Kidney Failure: 7878

Related Diseases

1.	Hypertension (High Blood Pressure)
2.	Heart Failure
3.	Proteinuria
4.	Secondary Hyperparathyroidism
5.	Anemia

Experts

1.	Ritz, Eberhard: 6 articles (08/2006 - 02/2002)
2.	Ritz, E: 5 articles (10/2001 - 01/2000)
3.	Weissgarten, Joshua: 4 articles (07/2007 - 01/2004)
4.	Efrati, Shai: 4 articles (07/2007 - 01/2004)
5.	Averbukh, Zhan: 4 articles (07/2007 - 01/2004)
6.	Golik, Ahuva: 4 articles (07/2007 - 01/2004)
7.	Berman, Sylvia: 4 articles (07/2007 - 01/2004)
8.	Deray, Gilbert: 4 articles (12/2006 - 11/2003)
9.	Launay-Vacher, Vincent: 4 articles (12/2006 - 11/2003)
10.	Amann, Kerstin: 4 articles (08/2006 - 09/2002)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Kidney Failure:

1.	CreatinineIBA 06/01/1998 - "Renal failure responded favorably over weeks to corticosteroid therapy (serum creatinine level, 2.8 mg/dL) with a marked reduction in bilateral renal enlargement by CT scan." 10/01/2007 - "A non-significant improvement in creatinine clearance at six months was also observed in patients with renal failure prior to treatment: 48.7 +/- 17.1 ml/min vs. 69.2 +/- 160.3. " 09/01/1999 - "Lp(a) levels were significantly greater in patients with moderate renal failure (21.7+/-23.9 mg/dl) as compared with patients with normal renal function (15.6+/-16.4 mg/dl, P<0.001), and an inverse correlation was observed between log Lp(a) and creatinine clearance (r = -0.181, P <0.01). " 10/01/1996 - "MEASUREMENTS: 1) Renal remission (defined as < 10 dysmorphic erythrocytes per high-power field, the absence of cellular casts, and excretion of < 1 g of protein per day without doubling of the serum creatinine level), 2) prevention of doubling of the serum creatinine level, and 3) prevention of renal failure requiring dialysis. " 01/01/1992 - "Actually, retrospective analysis of 167 over 625 cases records from 1981 to 1985 and of 178 over 700 case records from 1986 to 1990 in the Department of Nephrology, Necker Hospîtal, plasma creatinine concentration at initiation of dialysis of the two period was 1044 +/- 17 and 981 +/- 13 mol/L respectively, corresponding to a creatinine clearance of 6 and 7 ml/min. It is clear now that management of chronic renal failure patients should be considered as a whole and initiation of dialysis is the end point of this global strategy. " Order ALL the reference details at left...
2.	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 11/01/2000 - "It is noted that several studies indicate that angiotensin-converting enzyme inhibitors may be more effective in preventing or retarding renal failure than other conventional drugs. " 05/01/1995 - "Further comparative trials are needed to fully determine its efficacy with respect to other ACE inhibitors, and a better understanding of its effects on renal function will clarify its role in hypertensive patients with renal failure." 01/01/1990 - "Angiotensin-converting enzyme inhibitors: therapeutic implications in the management of chronic renal failure." 11/01/2001 - "Recent studies had shown that tight blood pressure control, intensive glycemic control, and use of angiotensin converting enzyme inhibitors in diabetic patients significantly reduced not only the rate of progressive renal failure, but also substantially reduced the cost of complications and led to higher cost effectiveness. " 01/01/1999 - "Furthermore, a number of trials have shown that ACE-inhibitors (ACEi) may reduce the rate of progression of renal failure. " Order ALL the reference details at left...
3.	Cyclophosphamide (Cytoxan)FDA LinkGeneric 05/01/2007 - "However, the cumulative incidence of persistent complete remission (>2 years without medication) increased over time (35% at 2 years, 52% at 6 years, and 71% at 15 years after the start of cyclophosphamide therapy), and no patient developed kidney failure. " 01/01/1994 - "At 21 months after such therapeutic regimen in 10 out of 12 patients a complete clinical remission was found, in one patient a partial response with persistent moderate renal failure occurred, while one patient was refractory even to the additional administration of cyclophosphamide. " 07/01/2007 - "RESULTS: There were no differences in the outcomes of death, renal failure, reversal or relapse of active renal disease, or toxicity in those using or not using cyclophosphamide. " 09/01/2000 - "Myopericarditis caused by cyclophosphamide used to mobilize peripheral blood stem cells in a myeloma patient with renal failure." 01/01/2000 - "Cyclophosphamide was administered i.v. in the dose 0.75 g/m2 b.s., no more than 1.0 g per dose, in renal failure 0.5 g/m2. " Order ALL the reference details at left...
4.	Urea (Carbamide)FDA LinkGeneric 07/01/1997 - "4. In clinical urea kinetic studies in a healthy subject and in a renal failure patient without residual renal function, reproducible values of the distribution volume, production rate and clearance of urea were determined using minimal amounts of [13C]urea (25-50 mg). " 07/01/1997 - "We devised a urea dilution for measurement of the distribution volume, production rate and clearance of urea in healthy subjects and renal failure patients using the inexpensive single labelled [13C]urea isotope with subsequent analysis by headspace chromatography-isotope ratio MS (GC-IRMS) of the [13C]urea enrichment. " 11/01/1991 - "OBJECTIVE: To document the efficacy of continuous arteriovenous hemofiltration with dialysis following renal failure, without protein restriction, and to explore the magnitude and clinical applications of total daily urea clearance. " 07/01/1997 - "5. Because only low [13C]urea enrichments are needed in this urea dilution method using GC-IRMS analysis, the costs of urea kinetic studies are reduced considerably, especially in patients with renal failure." 04/01/2007 - "The aims were to investigate the effects of early and late experimental renal failure on the regulation of hepatic urea synthesis and the expression of urea cycle enzyme genes in the liver. " Order ALL the reference details at left...
5.	CalciumIBA 12/01/2004 - "In the 27-week study, high calcium intake decreased blood pressure, retarded progression of renal failure, reduced glomerulosclerosis, interstitial damage, and aortic calcifications, and improved survival from 50% to 92% in NTX rats. " 11/01/1980 - "[A study on calcium metabolism in renal failure--clinical aspects and treatment (author's transl)]" 02/01/1978 - "[Experimental study of calcium metabolism in renal failure. " 04/01/1973 - "Study of intestinal absorption of calcium in patients with renal failure." 01/01/2008 - "Calcium antagonists and renal failure progression." Order ALL the reference details at left...
6.	Dietary ProteinsIBA 11/01/1989 - "Dietary protein restriction is effective in maintaining normal or only slightly elevated serum lipid levels in patients with early renal failure. " 12/01/1995 - "Studies are needed to establish the safe level of dietary protein restriction in these patients and to assess the efficacy of such restriction in slowing the progression of renal failure." 10/01/2005 - "BACKGROUND: Spontaneous reduction in dietary protein intake is a recognized feature of severe renal failure, and previous studies have suggested that this may occur at an early stage of renal functional decline. " 11/01/1996 - "What role does dietary protein restriction play in the management of chronic renal failure in dogs?" 01/01/1994 - "Effect of dietary protein restriction on the progression of renal failure: a prospective randomized trial." Order ALL the reference details at left...
7.	SteroidsIBA 05/01/2006 - "The diagnosis was confirmed by skin biopsy, and treatment with statins and steroids proved effective, as renal failure progressively improved. " 06/01/1995 - "However, four of 10 patients whose renal failure initially improved, failed to respond to definitive therapy, and died 3 to 4 weeks after cessation of the steroids. " 02/01/2000 - "In a study on the use of steroids for patients with progressive moderate renal dysfunction caused by Chinese herbs, Vanherweghem et al. reported that the progression of renal failure was appreciably slowed in patients given steroids when compared with the control group. " 04/01/2009 - "Although we administered steroids to her, her general condition deteriated and she died of postrenal renal failure 37 days after the operation. " 04/01/2001 - "Their renal failure responded to treatment with steroids, enabling withdrawal of dialysis within 10 days. " Order ALL the reference details at left...
8.	Calcitriol (Calcijex)FDA LinkGeneric 08/01/1980 - "The data show that a small dose of calcitriol is safe and effective for the management of the derangements of divalent ion metabolism in patients with moderate renal failure." 12/01/1991 - "In this study, the effect of calcitriol on the calcemic response to PTH was evaluated in normal rats and in rats with moderate and advanced renal failure. " 08/01/1989 - "Previous studies from our laboratory have demonstrated that metabolic clearance rate (MCR) of calcitriol is decreased in experimental renal failure. " 01/01/1980 - "Direct feed-back regulation of PTH-secretion by 1,25-dihydroxyvitamin D3 in renal failure: a controlled trial." 08/01/2005 - "AIM: Renal production of 1,25-dihydroxycholecalciferol is attenuated in early renal failure. " Order ALL the reference details at left...
9.	NitrogenIBA 01/01/1979 - "Conservative management of chronic renal failure in children is essentially based on dietary prescription including recommendations for high caloric intake and a certain limitation of protein intake according to GFR in order to avoid any extra loading with nitrogen wastes. " 07/01/1994 - "Low nitrogen diets preserve nutritional status but not residual renal function in rats with severe renal failure." 01/01/1994 - "These results indicate that administration of EAA alone for treatment of renal failure needs high-calorie and low-nitrogen conditions such as Cal/N 600 for avoiding complications. " 07/01/1992 - "Full protein alimentation and nitrogen equilibrium in a renal failure patient treated with continuous hemodiafiltration: a case report of 67 days of continuous hemodiafiltration." 07/01/1991 - "These results suggest that negative nitrogen balance during the initial few weeks does not predict future nutritional status of patients with diabetic renal failure." Order ALL the reference details at left...
10.	Insulin (Novolin)FDA Link 09/01/2007 - "The metabolic mayhem of severe acute illness has many parallels with those induced by kidney failure itself, and patients with kidney failure are at increased risk from many of the complications potentially improved by insulin therapy. " 09/01/2007 - "We reviewed the potential benefits of intensive insulin therapy and examined the published trials for data directly applicable to patients with kidney failure. " 01/01/1985 - "Although most patients in both studies were insulin-treated type-1 diabetics, death due to renal failure was observed only in 7%. " 04/01/1981 - "The study comprised 121 insulin-dependent diabetics with renal failure (mean age at onset of diabetes 13.4 leads to 7.6 (SD) years, mean pre-uraemic duration of diabetes 21.7 leads to 4.7 years), and 36 insulin-dependent diabetics (mean age at onset of diabetes 16.5 leads to 8.4 years) without renal failure despite long mean duration of diabetes (32.5 leads to 5.1 years). " 03/01/2008 - "It seems that the puberty growth spurt in adolescents both with normal health and renal failure may require increased insulin secretion as one of its hormonal requirements. " Order ALL the reference details at left...

Therapies and Procedures

1.	Renal Dialysis (Hemodialysis) 06/01/1995 - "Seventeen (53%) patients attained a complete remission and 22 (69%) survived (five in advanced renal failure and long-term hemodialysis). " 06/01/2009 - "In renal failure animal models, acid-base parameters improved significantly after hemodialysis with ionized alkaline water compared with the conventional water treated with reverse osmosis (RO). " 08/01/1992 - "The accumulation of this E-21 IA in renal failure is evidence that the kidney has a major role in the clearance of this fragment, which is not accomplished by the membranes used in hemodialysis." 04/01/2003 - "Depolymerized holothurian glycosaminoglycan (DHG), a novel alternative anticoagulant for hemodialysis, is safe and effective in a dog renal failure model." 03/01/2004 - "BACKGROUND AND AIM OF THE STUDY: The safety and efficacy of beating-heart valve surgery as a myocardial protection strategy was evaluated in patients with renal failure requiring hemodialysis. " Order ALL the reference details at left...
2.	Kidney Transplantation 04/01/2009 - "INTRODUCTION: Renal transplantation is the best treatment for kidney failure. " 08/01/2007 - "Kidney transplantation is the best option for all patients with terminal renal failure. " 01/09/2006 - "BACKGROUND: Preemptive kidney transplantation (PreKT) before initiation of chronic dialysis has been examined recently with favorable results as the most effective treatment for kidney failure. " 05/01/2006 - "Combined liver kidney transplantation (LKT) has the potential to provide a complete recovery of liver and kidney failure; the literature reports an increase in LKT in the last few years and an improvement in patient and graft survival. " 08/01/2003 - "RESULTS: Their sexual functions, significantly aggravated after renal failure, were improved after kidney transplantations, but failed to return to normal. " Order ALL the reference details at left...
3.	Transplants (Transplant) 06/01/2006 - "As most mito-mice without a transplant died due to renal failure, we examined whether transplanted bone marrow cells transdifferentiated into renal tissues carrying improved renal function. " 01/01/2005 - "The dual transplant has cured his diabetes and renal failure and has had a beneficial effect on his neuropathy, retinopathy and quality of life. " 12/01/1991 - "It is a drug with great promise for its specific indications, but more studies in renal failure and organ transplant patients are needed to firmly establish its efficacy in these populations." 07/01/2006 - "Pancreas transplant (Ptx) is the gold standard for the treatment of type I diabetes, mainly when associated with renal failure. " 10/01/1977 - "Thus the performance of 1,000 renal transplants at this center has resulted not only in rehabilitation of many renal failure patients, but also in expanded and improved research and teaching capabilities, bringing support from multiple medical disciplines and the general community." Order ALL the reference details at left...
4.	Transplantation (Transplant Recipients) 01/01/1997 - "For patients with FHF undergoing transplantation, pretransplant renal failure strongly predicts poor outcome with significantly greater consumption of resources." 09/01/2005 - "The inadequacy of current treatment modalities and insufficiency of donor organs for cadaveric transplantation have driven a search for improved methods of dealing with renal failure. " 07/01/2003 - "It must be emphasized that P/K transplantation is not a cure for renal failure and diabetes, rather, it is a treatment option. " 06/18/1977 - "Management of chronic renal failure by dialysis and transplantation." 03/01/2009 - "The objective of this study was to describe the baseline physical function in older adults with renal failure referred for transplantation and compare them with older adults with other significant comorbidity. " Order ALL the reference details at left...
5.	Peritoneal Dialysis 06/01/1986 - "In the patients without renal failure, low-flow peritoneal dialysis (one exchange per day) seemed to be of some value in maintaining remission but was ineffective in treating more active disease. " 01/01/1990 - "Peritoneal dialysis is effective in the newborn period in the management of metabolic disturbances as well as renal failure. " 06/01/1996 - "The success of peritoneal dialysis in the management of chronic renal failure depends on the proper function of the implanted catheter. " 06/01/1992 - "To evaluate the efficacy of peritoneal dialysis (PD) in the management of post-traumatic renal failure, the authors reviewed the courses of five critically injured patients treated with PD over an 18-month period. " 06/01/1978 - "Chronic peritoneal dialysis in the management of chronic renal failure." Order ALL the reference details at left...

Best Treatments:
Research Summary Report
on Kidney Failure

CureHunter Patient-Physician Summary Reports collect in one document all the medications ever reported in the US National Library of Medicine—1949 to the present—to be effective against your target disease. CureHunter research summary reports will vary in length from 25 to 250 pages. Analytic charts allow you and your physicians to see at a glance your medication options—including new, promising, off-label and experimental all rated for clinical efficacy.

Free Updates for 1 Year
All 647 Outcomes
Top 200 Key Drugs and Biologics
Top 50 Key Therapies and Procedures
Detailed History Charts
Full Research Reference Details
Sample PDF Report on Psoriasis >>

Price:

$24.00 & Delivery via PDF download
updates for 1 year

Research Interface

Rapidly retrieve summaries of all the evidence for any disease in seconds. Save hours of search and analysis time. CureHunter is unlike any "search engine" you have ever used. Where standard "search engines" produce lists of links, CureHunter quantifies evidence, extracts it from the literature and calculates a result you can use to immediately facilitate evidence based decision making in Real Clinical Time.

Unlimited Disease, Drug and Therapy Search
2 clicks from Disease to Drug to Evidence
Trial References
All the Positive Outcomes
Detailed Relationship Timeline Charts
Full Article Reference Details
Includes Mobile Interface Subscription
One-click to FDA Products/Patents
Request Institution License Details >>

Price:

$490.00 access via web interface
1 year subscription

Proceed to Checkout >>

Mobile Interface

Retrieve summaries of all the evidence for any disease from your Mobile Phone or PDA. Accelerate decision making in the field. Speed up your study of new drug and disease domains. Refresh your knowledge on the road.

Access from any web enabled PDA or Phone
Trial references
All the Positive Outcomes
Drug and Therapy searches
Full Article Reference Details
Try Mobile Interface >>

Price:

$45.00 access via "curehunter.com/m"
1 year subscription

Proceed to Checkout >>