HOMEPRODUCTSSERVICESCOMPANYCONTACTFAQResearchDictionaryPharmaMobileSign Up FREE or Login

Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase

A group of related enzymes responsible for the endohydrolysis of the di-N-acetylchitobiosyl unit in high-mannose-content glycopeptides and GLYCOPROTEINS.
Also Known As:
Endo D Endoglucosaminidase; Endo F Endoglucosaminidase; Endo H Endoglucosaminidase; Endo-N-Acetyl-beta-d-glucosaminidase; Endo-beta-N-Acetylglucosaminidase D; Endo-beta-N-Acetylglucosaminidase F; Endo-beta-N-Acetylglucosaminidase H; Endoglucosaminidase D; Endoglucosaminidase F; Endoglucosaminidase H; Endoglucosidase H; Endoglycosidase D; Endohexosaminidase F; Endohexosaminidase H; Peptide N-Glycosidase F; Di N Acetylchitobiosyl beta N Acetylglucosaminidase; Endo N Acetyl beta d glucosaminidase; Endo beta Acetylglucosaminidase; Endo beta N Acetylglucosaminidase D; Endo beta N Acetylglucosaminidase F; Endo beta N Acetylglucosaminidase H; Endo-beta-N-Acetylglucosaminidase, Mannosyl-Glycoprotein; Mannosyl Glycoprotein Endo beta N Acetylglucosaminidase; Peptide N Glycosidase F; beta-N-Acetylglucosaminidase, Di-N-Acetylchitobiosyl; Di-N-Acetylchitobiosyl beta-N-Acetylglucosaminidase; Endo-beta-Acetylglucosaminidase; Endoglycosidase F; Glycopeptide-D-mannosyl-N(4)-(N-acetyl-D-glucosaminyl)2-asparagine 1,4-N-acetyl-beta-glucosaminohydrolase
Networked: 39 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Amoresano, Angela: 2 articles (01/2006 - 12/2003)
2. Casbarra, Annarita: 2 articles (01/2006 - 12/2003)
3. Pocheć, Ewa: 2 articles (01/2006 - 12/2003)
4. Lityńska, Anna: 2 articles (01/2006 - 12/2003)
5. Tang, Huiyuan: 1 article (01/2014)
6. Shao, Yuan: 1 article (01/2014)
7. Troyer, Dean A: 1 article (01/2014)
8. Mehta, Anand S: 1 article (01/2014)
9. Haab, Brian B: 1 article (01/2014)
10. Drake, Richard R: 1 article (01/2014)

Related Diseases

1. Carcinoma (Carcinomatosis)
2. Neoplasms (Cancer)
3. Infection
4. Hepatocellular Carcinoma (Hepatoma)
01/01/1988 - "When the hepatoma enzyme was treated with endo-beta-N-acetylglucosaminidase H, the acidic variant forms disappeared and were converted into forms identical to those of normal liver. "
04/01/1993 - "Digestion of both the normal rat hepatocytes and Zajdela hepatoma cells 100-kDa beta 1-precursors with endo-beta-N-acetylglucosaminidase H and peptide N-glycosidase yielded products from 100 kDa to 84 kDa and 82 kDa, respectively, as judged by SDS/PAGE, suggesting that the same polypeptide chain is synthesized in normal rat hepatocytes and in Zajdela hepatoma cells. "
11/15/1992 - "In both cell types DPP IV was initially synthesized as a 97-kDa precursor which was completely susceptible to digestion with endo-beta-N-acetylglucosaminidase H converting the molecular mass to 84 kDa. The precursor was processed to the mature forms of DPP IV, glycosylated with N-glycans mainly of the complex type with a half-life of 20-25 min. The transit of newly synthesized DPP IV to the cell surface displayed identical or very similar kinetics in both cell types with the major portion of DPP IV appearing at the cell surface after 60 min. DPP IV molecules were very slowly degraded in hepatocytes as well as in hepatoma cells with half-lives of approximately 45 h. "
01/01/2014 - "Formalin-fixed tissues from normal mouse kidney, human pancreatic and prostate cancers, and a human hepatocellular carcinoma tissue microarray were processed by antigen retrieval followed by on-tissue digestion with peptide N-glycosidase F. "
5. Teratocarcinoma

Related Drugs and Biologics

1. Glycoproteins (Glycoprotein)
2. Antigens
3. Staphylococcal Protein A (A, Protein)
4. Leucine (L-Leucine)
5. Glucosamine (Dona)
6. Polysaccharides
7. Oligosaccharides
8. Peptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine Amidase
9. Tunicamycin
10. Neuraminidase (Sialidase)

Related Therapies and Procedures

1. Microspheres (Microsphere)
2. Lasers (Laser)
3. Aftercare (After-Treatment)