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Protein Tyrosine Phosphatases

An enzyme group that specifically dephosphorylates phosphotyrosyl residues in selected proteins. Together with PROTEIN-TYROSINE KINASE, it regulates tyrosine phosphorylation and dephosphorylation in cellular signal transduction and may play a role in cell growth control and carcinogenesis.
Also Known As:
PTPase; Phosphotyrosyl Protein Phosphatase; Protein-Tyrosine Phosphatase; Phosphatase, Phosphotyrosine; Phosphatase, Phosphotyrosyl Protein; Phosphatase, Protein-Tyrosine; Phosphatase, Tyrosyl Phosphoprotein; Phosphatases, Protein Tyrosine; Phosphoprotein Phosphatase, Tyrosyl; Protein Phosphatase, Phosphotyrosyl; Protein Tyrosine Phosphatase; Tyrosine Phosphatases, Protein; Phosphotyrosine Phosphatase; Protein-Tyrosine-Phosphatase; Tyrosyl Phosphoprotein Phosphatase; Protein-tyrosine-phosphate phosphohydrolase
Networked: 1685 relevant articles (21 outcomes, 148 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Tremblay, Michel L: 18 articles (01/2021 - 12/2005)
2. Zhang, Zhong-Yin: 18 articles (12/2020 - 08/2003)
3. Neel, Benjamin G: 17 articles (01/2020 - 04/2002)
4. Scharl, Michael: 15 articles (08/2021 - 12/2009)
5. Lombroso, Paul J: 15 articles (01/2020 - 03/2007)
6. Bottini, Nunzio: 14 articles (01/2021 - 01/2002)
7. Mustelin, Tomas: 12 articles (01/2019 - 01/2002)
8. Lazo, John S: 11 articles (12/2020 - 02/2003)
9. Tonks, Nicholas K: 11 articles (01/2018 - 02/2003)
10. Sorio, Claudio: 10 articles (03/2022 - 02/2004)

Related Diseases

1. Insulin Resistance
2. Neoplasms (Cancer)
3. Type 2 Diabetes Mellitus (MODY)
4. Inflammation (Inflammations)
5. Glioma (Gliomas)

Related Drugs and Biologics

1. Glucose (Dextrose)
2. Insulin (Novolin)
3. Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
4. Protein-Tyrosine Kinases (Tyrosine Kinase)
5. 6-pyruvoyltetrahydropterin synthase (PTPS)
6. Enzymes
7. NSC-87877
8. Cholesterol
9. Triglycerides (Triacylglycerol)
10. Small Interfering RNA (siRNA)

Related Therapies and Procedures

1. Immunotherapy
2. Therapeutics
3. Drug Therapy (Chemotherapy)
4. Catheters
5. Caloric Restriction