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Swainsonine

An indolizidine alkaloid from the plant Swainsona canescens that is a potent alpha-mannosidase inhibitor. Swainsonine also exhibits antimetastatic, antiproliferative, and immunomodulatory activity.
Also Known As:
Swainsonine, (1R-(2 beta,8a alpha))-Isomer; Swainsonine, (2 beta,8a alpha)-Isomer; Swainsonine, (8 alpha)-Isomer; Swainsonine, (8 alpha,8a alpha)-Isomer; Swainsonine, (8a alpha)-Isomer; 1,2,8-Indolizinetriol, octahydro-, (1S-(1alpha,2alpha,8beta,8abeta))-
Networked: 140 relevant articles (4 outcomes, 16 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Gardner, Dale R: 6 articles (07/2014 - 06/2002)
2. Zhao, Baoyu: 3 articles (10/2015 - 07/2007)
3. Kalraiya, Rajiv D: 3 articles (05/2015 - 09/2006)
4. Lityńska, Anna: 3 articles (04/2015 - 01/2006)
5. Tong, Dewen: 3 articles (12/2012 - 07/2007)
6. Driemeier, David: 3 articles (01/2012 - 06/2002)
7. Asano, Naoki: 3 articles (07/2008 - 12/2003)
8. Oredipe, O A: 3 articles (11/2003 - 01/2003)
9. Sridhar, Rajagopalan: 3 articles (10/2003 - 01/2003)
10. Furbert-Harris, Paulette M: 3 articles (10/2003 - 01/2003)

Related Diseases

1. Neoplasms (Cancer)
2. Melanoma (Melanoma, Malignant)
3. Carcinoma (Carcinomatosis)
4. Neoplasm Metastasis (Metastasis)
5. Lymphangitis

Related Drugs and Biologics

1. mannosyl-oligosaccharide 1,3 - 1,6-alpha-mannosidase
2. alpha-Mannosidase (LAMAN)
3. Tunicamycin
4. Polysaccharides
5. Mannosidases
6. Doxorubicin (Adriamycin)
7. Pyrrolidines
8. Cisplatin (Platino)
9. Apolipoproteins E (ApoE)
10. Aminocaproic Acids (EAC)

Related Therapies and Procedures

1. Drug Therapy (Chemotherapy)
2. Heterologous Transplantation (Xenotransplantation)
3. Aftercare (After-Treatment)
4. Transplantation (Transplant Recipients)
5. Radiotherapy