|1.||Newman, Peter A: 7 articles (04/2009 - 05/2004)|
|2.||Duan, Naihua: 7 articles (04/2009 - 05/2004)|
|3.||Kim, Jerome H: 5 articles (09/2014 - 07/2012)|
|4.||Rudy, Ellen T: 5 articles (03/2006 - 05/2004)|
|5.||Montefiori, David C: 4 articles (03/2015 - 01/2002)|
|6.||Michael, Nelson L: 4 articles (09/2014 - 07/2012)|
|7.||Corey, Lawrence: 4 articles (12/2012 - 07/2003)|
|8.||Kent, Stephen J: 4 articles (09/2010 - 01/2005)|
|9.||Hudgens, Michael G: 4 articles (08/2006 - 07/2003)|
|10.||Stover, John: 3 articles (01/2015 - 01/2010)|
10/01/2004 - "Most current candidate HIV vaccines seem to produce little protection against infection, but reduce viral load and slow the decline in CD4 lymphocyte numbers. "
01/01/2011 - "T cell directed HIV vaccines are based upon the induction of CD8+ T cell memory responses that would be effective in inhibiting infection and subsequent replication of an infecting HIV-1 strain, a process that requires a match or near-match between the epitope induced by vaccination and the infecting viral strain. "
08/01/1996 - "Protection against disease or persistent infection may be achieved in the absence of sterilizing immunity, suggesting that new benchmarks for AIDS vaccines may be in order."
04/01/2005 - "Because there is no laboratory assay that will predict whether an HIV vaccine can protect humans from infection, clinical trials involving thousands of volunteers will need to be conducted to determine the efficacy of HIV vaccines. "
11/01/2014 - "These results suggest that combining oral PrEP with HIV vaccines could enhance protection against HIV-1 infection."
|2.||Acquired Immunodeficiency Syndrome (AIDS)
01/01/1993 - "Many knowledgeable people believe that the only real hope for halting the AIDS pandemic rests with safe and effective HIV vaccines that are delivered through a global immunization programme. "
05/01/1996 - "The goal of developing a safe and effective AIDS vaccine will likely occur when continued advances in understanding the immunopathogenesis of HIV is balanced with a healthy dose of empirical testing of innovative candidate AIDS vaccines."
12/01/2003 - "In particular, recent studies aimed at establishing the efficacy of new AIDS therapies, or AIDS vaccines, applied lower ethical standards than those formulated by the Declaration of Helsinki of the World Medical Association, and accepted in the US and internationally,--although American researchers and institutions were involved in these studies. "
05/01/2015 - "Identification and characterization of CD8(+) T cells effectively controlling HIV-1 variants are necessary for the development of AIDS vaccines and for studies of AIDS pathogenesis, although such CD8(+) T cells have been only partially identified. "
06/23/2010 - "Data were collected on demographics, behaviors, perceptions about HIV/AIDS and HIV vaccines, and concerns about participation in HIV vaccine clinical trials. "
|3.||HIV Infections (HIV Infection)
06/01/1995 - "In order to prove the efficacy of human immunodeficiency virus (HIV) vaccines, it will be necessary to do large-scale trials in populations at high risk of acquiring HIV infection. "
01/01/2007 - "Although live attenuated HIV vaccines are unlikely to be developed due to a myriad of safety concerns, opportunities exist to better understand the correlates of immune protection against HIV infection by studying rare cohorts of long-term survivors infected with attenuated, nef-deleted HIV strains such as the Sydney blood bank cohort (SBBC). "
09/01/2013 - "The purpose of the current review is to critique recent developments in the use of animal models of HIV infection in preclinical studies of AIDS vaccines and to describe how the use of improved animal models can inform the development of an HIV vaccine. "
01/01/2015 - "This study presents modeling results exploring the potential impact of HIV vaccines in the Chinese context at varying efficacy and coverage rates, while further exploring the potential implications of vaccination programs aimed at reaching populations at highest risk of HIV infection. "
09/16/2014 - "Efficacy trials of adenovirus 5-vectored candidate HIV vaccines [recombinant Ad5 (rAd5)-HIV] were halted for futility due to lack of vaccine efficacy and unexpected excess HIV infections in the vaccine recipients. "
02/15/2006 - "Analysis of the frequency of directly cytotoxic HIV-specific T cells may be of considerable value in the assessment of disease progression and the potential efficacy of HIV vaccines."
09/23/2013 - "Therapeutic human immunodeficiency virus (HIV) vaccines aim to reduce disease progression by inducing HIV-specific T cells. "
01/01/2005 - "The results also support the concept that neonatal immunization with HIV vaccines might modulate disease progression in infants infected with HIV by breast-feeding."
01/17/2002 - "Potent virus-specific cytotoxic T lymphocyte (CTL) responses elicited by candidate AIDS vaccines have recently been shown to control viral replication and prevent clinical disease progression after pathogenic viral challenges in rhesus monkeys. "
10/01/2004 - "Studies of human immunodeficiency virus (HIV) vaccines in animal models suggest that it is difficult to induce complete protection from infection (sterilizing immunity) but that it is possible to reduce the viral load and to slow or prevent disease progression following infection. "
|5.||Communicable Diseases (Infectious Diseases)
12/01/2005 - "The acquired immunodeficiency syndrome (AIDS) has now become one of the most serious infectious disease in the world, the safe and effective AIDS vaccines would be the best tools to control the disease. "
05/26/2010 - "Historically, effective vaccines have focused on eliciting pathogen epitope-specific acquired immune responses to protect against infectious diseases; however, such traditional approaches to developing HIV vaccines have been unsuccessful. "
01/01/2012 - "To prevent important infectious diseases such as tuberculosis, malaria and HIV, vaccines inducing greater T cell responses are required. "
07/30/1999 - "A meeting was organized by the Joint United Nations Programme on HIV/AIDS (UNAIDS), the World Health Organisation (WHO) and the Japanese National Institute of Infectious Diseases (NIID) with the following objectives: (i) to discuss public health and economic rationale to accelerate the development and evaluation of HIV vaccines suitable for use in Asia; (ii) to review ongoing preclinical HIV vaccine research in Asia; (iii) to review the Asian experience in conducting clinical trials of HIV candidate vaccines; (iv) to explore possibilities for international collaboration between countries in the region and with other countries and institutions; and (v) to discuss issues related to availability of future effective HIV vaccines. "
|1.||Anti-Infective Agents (Microbicides)
|7.||MF59 oil emulsion
|9.||Proteins (Proteins, Gene)
|10.||Surface Antigens (Surface Antigen)
|2.||Drug Therapy (Chemotherapy)
|3.||Male Circumcision (Circumcision)