|1.||Acquired Immunodeficiency Syndrome (AIDS)
|3.||HIV Infections (HIV Infection)
|1.||Sarfati, C: 7 articles (08/2010 - 03/2000)|
|2.||Weiss, Louis M: 7 articles (07/2010 - 01/2002)|
|3.||Sarfati, Claudine: 4 articles (07/2010 - 06/2002)|
|4.||Derouin, Francis: 4 articles (07/2010 - 06/2002)|
|5.||Didier, Elizabeth S: 4 articles (10/2006 - 04/2005)|
|6.||Didier, E S: 4 articles (06/2006 - 02/2004)|
|7.||Menotti, Jean: 3 articles (07/2010 - 05/2003)|
|8.||Leitch, G J: 3 articles (02/2009 - 01/2001)|
|9.||Brindley, Paul J: 3 articles (06/2006 - 05/2005)|
|10.||Didier, Peter J: 3 articles (06/2006 - 05/2005)|
|1.||Albendazole (Albenza)FDA Link
06/01/1995 - "However, good results are obtained with Albendazole in intestinal microsporidiosis."
07/01/2008 - "This case of microsporidiosis manifested as mutiple intracranial lesions separated in space and time, and neurological and radiological findings were improved with albendazole administration. "
11/01/1994 - "Since patients infected with Encephalitozoon spp. are known to respond favorably to albendazole, identification of the parasite to the species level would be invaluable in the treatment of disseminated microsporidiosis."
01/01/2013 - "To evaluate the possibility latent microsporidiosis, efficacy or albendazole, and reactivation, the authors monitored the course of E. "
01/01/2013 - "Latent microsporidiosis caused by Encephalitozoon cuniculi in immunocompetent hosts: a murine model demonstrating the ineffectiveness of the immune system and treatment with albendazole."
06/01/2006 - "These results thus support continued studies to identify more effective fumagillin-related drugs for treating microsporidiosis."
11/01/1997 - "Our study allowed the identification of oral fumagillin as a potential treatment for intestinal microsporidiosis due to E. "
12/01/2013 - "We report the first successful use, to our knowledge, of fumagillin alone in a pediatric patient to cure intestinal microsporidiosis in a liver-kidney transplanted child. "
12/01/2012 - "Fumagillin is an effective treatment against Enterocytozoon bieneusi, one of the two main species causing the microsporidiosis involved in human diseases. "
06/01/2006 - "Therapies for microsporidiosis in humans are limited, and fumagillin, which appears to be the most broadly effective antimicrosporidial drug, is considered to be moderately toxic. "
|3.||Thalidomide (Thalomid)FDA Link
06/01/1997 - "Thalidomide: a novel therapy for microsporidiosis."
07/01/1998 - "Thalidomide shows a significant ability to eliminate painful mouth ulcers in HIV patients and is also effective in reversing wasting and clearing up severe diarrhea caused by microsporidiosis. "
09/01/1998 - "In HIV-positive people, Thalidomide has been shown effective in treating mouth, throat, vaginal, and rectal ulcers, and has also been successful in clearing severe diarrhea-causing microsporidiosis infections. "
06/01/1997 - "Fecal tumor necrosis factor alpha (TNF-alpha) is elevated in microsporidiosis; therefore, thalidomide, an anti-TNF-alpha agent, was used as therapy. "
05/01/2000 - "Once the anti-inflammatory, immuno-modulatory, anti-TNF-alpha and anti-angiogenic properties of thalidomide were discovered, it was also tried in AIDS and related wasting, apthous ulcers, microsporidiosis and Kaposi's sarcoma. "
06/01/2005 - "Current therapies for microsporidiosis include albendazole, a benzimidazole that inhibits microtubule assembly and is effective against several microsporidia, including the Encephalitozoon spp., although it is less effective against Encephalitozoon bieneusi. "
04/01/2005 - "Current therapies for microsporidiosis include albendazole which is a benzimidazole that inhibits microtubule assembly and is effective against several microsporidia, including the Encephalitozoon species, but is less effective against E. "
10/01/2006 - "Benzimidazoles are not active against Enterocytozoon bieneusi, the most common cause of human microsporidiosis. "
10/01/1995 - "The need for an effective compound for the prevention and treatment of cryptosporidiosis in humans and animals has led to the testing of benzimidazoles based on reports that albendazole was clinically effective against related protozoan parasites causing microsporidiosis in humans. "
10/01/2006 - "Current therapies for microsporidiosis include benzimidazoles, which bind tubulin-inhibiting microtubule assembly, and fumagillin and its derivatives, which bind and inhibit methionine amino peptidase type 2 (MetAP2). "
|7.||Atovaquone (Mepron)FDA Link
06/01/1996 - "Atovaquone is effective treatment for the symptoms of gastrointestinal microsporidiosis in HIV-1-infected patients."
06/01/1996 - "Atovaquone demonstrates promise as a symptomatic treatment for intestinal microsporidiosis. "
06/01/1996 - "To report the clinical response to atovaquone in HIV-1-infected patients with symptomatic intestinal microsporidiosis. "
06/01/1996 - "A retrospective review of a cohort of AIDS patients with symptomatic intestinal microsporidiosis who received atovaquone. "
|9.||Interferon-gamma (Interferon, gamma)IBA
06/01/2008 - "The efficacy of gamma interferon (IFN-gamma) for the treatment of microsporidiosis caused by Encephalitozoon cuniculi was studied by means of adoptive transfer and IFN-gamma administration in SCID mice. "
06/01/2008 - "Efficacy of gamma interferon and specific antibody for treatment of microsporidiosis caused by Encephalitozoon cuniculi in SCID mice."
|10.||Furazolidone (Furoxone)FDA Link
|1.||Highly Active Antiretroviral Therapy (HAART)
03/01/2009 - "This study thus highlighted the limited genetic diversity among Australian Enterocytozoon bieneusi isolates, and it is hypothesized that, due to the reduced incidence of microsporidia and the subsequent reduction in the human reservoir of the anthroponotic genotype B, locally acquired intestinal microsporidiosis will rarely be seen in HIV-infected persons undergoing highly active antiretroviral therapy in the future in Australia."
11/01/2007 - "Limited data exist regarding the incidence of intestinal microsporidiosis following the introduction of highly active antiretroviral therapy (HAART) in Australia. "
11/01/1997 - "Remission of AIDS-associated intestinal microsporidiosis with highly active antiretroviral therapy."
11/01/2007 - "Declining incidence of intestinal microsporidiosis and reduction in AIDS-related mortality following introduction of HAART in Sydney, Australia."
10/01/2001 - "It was concluded that the microsporidiosis was a pre-existing opportunistic infection, whose presence was unmasked by a form of immune restoration induced by HAART."
03/01/2015 - "Microsporidiosis is rarely encountered in a corneal graft and masquerades as acute graft rejection. "
11/01/2014 - "Microsporidiosis in pediatric renal transplant patients in Cape Town, South Africa: two case reports."
04/01/2011 - "Previously reported cases of microsporidiosis in organ transplant recipients have also been reviewed, highlighting the necessity of considering organ transplant recipients a risk group for microsporidiosis. "
02/01/2009 - "Microsporidiosis in solid organ transplant recipients: two Enterocytozoon bieneusi cases and review."
02/18/2014 - "Microsporidiosis is now recognized as an emerging transplant-associated disease and should be considered in febrile transplant recipients when tests for routinely encountered agents are unrevealing. "
|3.||Drug Therapy (Chemotherapy)
03/10/2003 - "This study will be valuable for further work in biochemistry and immunology in addition to chemotherapy for microsporidiosis humans and animals."
01/01/2013 - "These findings stress the danger of latent microsporidiosis as a life-threatening risk factor especially for individuals undergoing chemotherapy and in transplant recipients of organs originating from infected donors."
01/01/2011 - "We have documented that microsporidiosis with intestinal mucosa disruption is frequent in patients undergoing concomitant anti-tumor necrosis factor/disease-modifying anti-rheumatic drug therapy. "
|5.||Transplantation (Transplant Recipients)
07/01/2015 - "Intestinal microsporidiosis in renal transplant recipients: Prevalence, predictors of occurrence and genetic characterization."
10/01/2013 - "Disseminated microsporidiosis in a renal transplant recipient: case report and review of the literature."
04/01/2012 - "To our knowledge, 5 cases of disseminated microsporidiosis with Encephalitozoon species have been reported worldwide in transplant recipients. "
04/01/2012 - "Disseminated microsporidiosis with Encephalitozoon species in a renal transplant recipient."
04/01/2011 - "Here, we describe the first cases of intestinal microsporidiosis by Enterocytozoon bieneusi genotype D in two non-HIV-infected renal transplant recipients from Spain. "