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tau Proteins (tau Protein)

Microtubule-associated proteins that are mainly expressed in neurons. Tau proteins constitute several isoforms and play an important role in the assembly of tubulin monomers into microtubules and in maintaining the cytoskeleton and axonal transport. Aggregation of specific sets of tau proteins in filamentous inclusions is the common feature of intraneuronal and glial fibrillar lesions (NEUROFIBRILLARY TANGLES; NEUROPIL THREADS) in numerous neurodegenerative disorders (ALZHEIMER DISEASE; TAUOPATHIES).
Also Known As:
tau Protein; Protein, tau; Proteins, tau
Networked: 2605 relevant articles (26 outcomes, 176 trials/studies)

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Bio-Agent Context: Research Results

Experts

1. Mandelkow, Eckhard: 37 articles (08/2015 - 02/2004)
2. Trojanowski, John Q: 36 articles (09/2014 - 06/2002)
3. Avila, Jesús: 32 articles (01/2016 - 02/2002)
4. Lee, Virginia M-Y: 32 articles (09/2014 - 06/2002)
5. Novak, Michal: 28 articles (07/2015 - 01/2003)
6. Mandelkow, Eva-Maria: 28 articles (01/2015 - 01/2002)
7. Goedert, Michel: 28 articles (09/2014 - 10/2002)
8. Binder, Lester I: 26 articles (12/2013 - 04/2002)
9. Iqbal, Khalid: 23 articles (03/2014 - 02/2002)
10. Kuret, Jeff: 21 articles (01/2016 - 07/2003)

Related Diseases

1. Alzheimer Disease (Alzheimer's Disease)
2. Tauopathies
3. Neurodegenerative Diseases (Neurodegenerative Disease)
4. Dementia (Dementias)
5. Amyloid Plaque

Related Drugs and Biologics

1. Amyloid (Amyloid Fibrils)
2. Peptides
3. Apolipoproteins E (ApoE)
4. Amyloid beta-Peptides
5. Protein Isoforms (Isoforms)
6. Paclitaxel (Taxol)
7. Lithium
8. Curcumin
9. Adrenocorticotropic Hormone (ACTH)
10. demethoxycurcumin

Related Therapies and Procedures

1. Immunotherapy
2. Drug Therapy (Chemotherapy)
3. Lasers (Laser)
4. Adjuvant Chemotherapy
5. Aftercare (After-Treatment)