|1.||Acquired Immunodeficiency Syndrome (AIDS)
10/01/1993 - "Effect of a recombinant CD4-IgG on in vitro T helper cell function: data from a phase I/II study of patients with AIDS."
07/01/1992 - "[Recombinant CD4-IgG in the treatment of AIDS and correlated syndromes: 1st stage of the study]."
10/01/1993 - "Ten patients with AIDS were enrolled in a phase I/II protocol of recombinant CD4-IgG (rCD4-IgG) treatment. "
01/01/1990 - "Designing CD4 immunoadhesins for AIDS therapy."
02/09/1989 - "Designing CD4 immunoadhesins for AIDS therapy."
01/01/1992 - "Given its unique properties, particularly the ability of CD4-IgG to cross the placenta, we plan to focus future clinical efforts on preventing infection of newborns via maternal-fetal transfer of HIV."
01/01/1992 - "In vivo experiments show that CD4-IgG protects against HIV-I IIIB infection of chimpanzees when administered prior to viral challenge. "
08/01/1991 - "Here we report that pretreatment with CD4-IgG can prevent the infection of chimpanzees with HIV-1. "
03/01/1991 - "Inhibition of infection was also observed when HIV became attached to untreated U937 cells through the binding of CD4-IgG hybrid molecules to FcR. "
08/01/1991 - "As recombinant CD4-IgG, like the parent IgG molecule, efficiently crosses the primate placenta, it may be possible to set up an immune state in a fetus before HIV transfer occurs, thus preventing infection."
|3.||HIV Infections (HIV Infection)
|4.||Epstein-Barr Virus Infections
|1.||RNA (Ribonucleic Acid)
|2.||Immunoglobulin G (IgG)
|3.||HIV hyperimmune globulin