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CD4 Immunoadhesins

Chimeric molecules resulting from the fusion of recombinant soluble CD4 to the Fc portion of immunoglobulins. These have potential use in the therapy of AIDS since they possess both the gp120-binding and HIV-blocking properties of rCD4 as well as the long plasma half-life and Fc receptor-binding functions of immunoglobulin.
Also Known As:
CD4 IgG; CD4-IgG; Immunoadhesins, CD4
Networked: 11 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Related Diseases

1. Acquired Immunodeficiency Syndrome (AIDS)
2. Infection
3. HIV Infections (HIV Infection)
4. Epstein-Barr Virus Infections
5. Tachycardia (Tachyarrhythmias)

Related Drugs and Biologics

1. RNA (Ribonucleic Acid)
2. Immunoglobulin G (IgG)
3. HIV hyperimmune globulin