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Cerebral Toxoplasmosis

Infections of the BRAIN caused by the protozoan TOXOPLASMA gondii that primarily arise in individuals with IMMUNOLOGIC DEFICIENCY SYNDROMES (see also AIDS-RELATED OPPORTUNISTIC INFECTIONS). The infection may involve the brain diffusely or form discrete abscesses. Clinical manifestations include SEIZURES, altered mentation, headache, focal neurologic deficits, and INTRACRANIAL HYPERTENSION. (From Joynt, Clinical Neurology, 1998, Ch27, pp41-3)
Also Known As:
Toxoplasmosis, Cerebral; Central Nervous System Toxoplasmosis; Toxoplasmoses, Cerebral; Toxoplasmosis, Intracranial; Intracranial Toxoplasmosis; Neurotoxoplasmosis; Toxoplasmosis, Central Nervous System
Networked: 236 relevant articles (15 outcomes, 20 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Acquired Immunodeficiency Syndrome (AIDS)
2. HIV Infections (HIV Infection)
3. Hypersensitivity (Allergy)
4. Pneumocystis Infections
5. Toxoplasmosis

Experts

1. Pereira-Chioccola, Vera Lucia: 6 articles (11/2015 - 10/2005)
2. Vidal, José E: 6 articles (09/2013 - 10/2005)
3. Pereira-Chioccola, Vera L: 4 articles (09/2013 - 07/2008)
4. Vidal, José Ernesto: 3 articles (11/2015 - 12/2009)
5. Peregudova, A B: 3 articles (01/2014 - 01/2007)
6. Hiramoto, Roberto M: 3 articles (09/2013 - 07/2008)
7. Meira, Cristina S: 3 articles (09/2013 - 07/2008)
8. Gava, Ricardo: 2 articles (11/2015 - 09/2013)
9. Motoie, Gabriela: 2 articles (11/2015 - 09/2013)
10. Menotti, Jean: 2 articles (05/2015 - 11/2003)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Cerebral Toxoplasmosis:
1. Pyrimethamine (Daraprim)FDA Link
2. Sulfadiazine (Sulphadiazine)FDA Link
3. Clindamycin (Cleocin)FDA LinkGeneric
4. Trimetrexate (JB11)FDA Link
5. Trimethoprim-Sulfamethoxazole Combination (Co-Trimoxazole)FDA LinkGeneric
6. Zidovudine (Retrovir)FDA LinkGeneric
7. Doxycycline (Vibramycin)FDA LinkGeneric
8. RoxithromycinIBA
9. Tetrahydrofolate Dehydrogenase (Dihydrofolate Reductase)IBA
10. TNFR-Fc fusion protein (etanercept)FDA Link

Therapies and Procedures

1. Aftercare (After-Treatment)
2. Transplants (Transplant)
3. Organ Transplantation
4. Highly Active Antiretroviral Therapy (HAART)
5. Transplantation (Transplant Recipients)