|1.||Crawford, E David: 9 articles (01/2015 - 02/2006)|
|2.||Persson, Bo-Eric: 7 articles (12/2014 - 12/2008)|
|3.||Zullo, Fulvio: 7 articles (10/2011 - 10/2002)|
|4.||Palomba, Stefano: 7 articles (10/2011 - 10/2002)|
|5.||Smith, Matthew R: 7 articles (12/2010 - 02/2002)|
|6.||Shore, Neal D: 6 articles (01/2015 - 12/2008)|
|7.||Klotz, Laurence: 6 articles (12/2014 - 03/2007)|
|8.||Neely, E Kirk: 6 articles (10/2012 - 05/2006)|
|9.||Boccon-Gibod, Laurent: 6 articles (07/2012 - 01/2007)|
|10.||Orio, Francesco: 6 articles (07/2008 - 10/2002)|
|1.||Prostatic Neoplasms (Prostate Cancer)
11/01/1984 - "A recent report on the efficacy of one of these analogues--leuprolide--in men with newly diagnosed metastatic prostatic cancer has revealed an initial response rate of 76 per cent (4% complete remissions, 32% partial remissions, and 40% stable) using National Prostatic Cancer Project criteria."
03/01/2014 - "Is high-dose leuprorelin acetate effective and safe in asian men with prostate cancer? "
01/01/1990 - "We conclude that the depot formulation of leuprolide is safe and effective in the treatment of advanced prostatic cancer, and that the safety and efficacy of this formulation do not differ significantly from those of the daily subcutaneous formulation."
03/01/1988 - "Maintenance of tumour-host equilibrium, and some degree of immunocompetency, in the presence of effective therapy with leuprolide, may prove beneficial in achieving more effective therapy in prostate cancer patients.(ABSTRACT TRUNCATED AT 250 WORDS)"
01/01/1990 - "The therapeutic efficacy and safety of various doses of leuprorelin acetate depot were determined in an open, multicentre study of patients with locally advanced or metastatic prostatic cancer (stages C, D1 or D2). "
01/01/1992 - "On the basis of this study, it can be concluded that leuprorelin acetate treatment is safe, well tolerated and effective in the medical management of endometriosis and endometriosis-related complaints."
10/01/1991 - "Although prolonged leuprolide therapy was clinically effective, its cost and the difficulty in early diagnosis of endometriosis may limit its use in nonhuman primate medicine."
03/01/2015 - "Leuprolide acetate is effective and safe in the treatment of endometriosis."
01/01/1994 - "The study results confirm the efficacy of leuprorelin acetate depot in the treatment of even advanced stages of endometriosis."
10/01/2015 - "In this study, we performed genome-wide gene expression profiling of clinical specimens of ovarian endometrioma to obtain insight into the effects of leuprolide acetate treatment. "
02/01/1989 - "The long-term safety of this treatment has not yet been established; however, leuprolide appears to be an effective long-term therapy for central precocious puberty."
10/01/1988 - "Efficacy of leuprolide therapy in children with central precocious puberty."
05/20/2015 - "Efficacy and safety of domestic leuprorelin in girls with idiopathic central precocious puberty: a multicenter, randomized, parallel, controlled trial."
12/01/2011 - "A randomized trial of 1- and 3-month depot leuprolide doses in the treatment of central precocious puberty."
10/01/1988 - "Although the long-term effects of leuprolide therapy cannot be determined with this study, it appears to be efficacious in the treatment of central precocious puberty."
04/01/2014 - "She then was placed on leuprolide acetate for 3 monthly cycles, but the tumor recurred 6 months after the leuprolide acetate was discontinued. "
01/01/2012 - "We suspected a correlation between the lack of tumor growth, application of leuprolide and the Raf-1/MEK/ERK-1/2-pathway. "
03/01/2001 - "by leuprorelin, could substantially prevent the appearance of liver tumors."
05/01/1999 - "Twenty-one-year-old nulligravida, diagnosed with endometrial stromal nodule, which decreased in size with leuprolide acetate treatment, underwent local excision of the tumor with preservation of reproductive function. "
05/01/1996 - "Leuprolide acetate may be active in the treatment of ovarian tumors of low malignant potential. "
01/01/2004 - "We carried out a longitudinal, interventional pilot study, examining the effect of leuprorelin acetate 3.75 mg (Prostap SR, Wyeth) on pelvic pain prospectively. "
01/01/1992 - "Scoring the final objective changes in the two patient groups revealed no significant difference, however the women treated with leuprorelin acetate depot registered significantly better control of pelvic pain. "
01/01/1999 - "Depot leuprolide was effective and safe for treating patients with chronic pelvic pain and clinically suspected endometriosis, confirming the potential of its empiric use in these patients."
01/01/1999 - "To evaluate and compare the safety and efficacy of leuprolide versus placebo in managing chronic pelvic pain in women with clinically suspected endometriosis. "
07/01/2006 - "Treatment with leuprolide acetate and hormonal add-back for up to 10 years in stage IV endometriosis patients with chronic pelvic pain."
|1.||Gonadotropin-Releasing Hormone (GnRH)
|7.||acetyl- 2- naphthylalanyl- 3- chlorophenylalanyl- 1- oxohexadecyl- seryl- 4- aminophenylalanyl(hydroorotyl)- 4- aminophenylalanyl(carbamoyl)- leucyl- ILys- prolyl- alaninamide
|4.||Palliative Care (Palliative Medicine)
|5.||Prostatectomy (Retropubic Prostatectomy)